| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009921
BDB009921
|
BDBM215441
CCN(CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C24H28Cl2N2O3 463.405000 |
DULNICHHRMGBFW-KIFXHHALSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215441; PubChem:CID58573893
|
Local ready
Direct docking supported
|
|
E3L009922
BDB009922
|
BDBM215442
CN(C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C22H24Cl2N2O3 435.351000 |
UXUFGOIKDTYLPE-SYYKKAFVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215442; PubChem:CID58573290
|
Local ready
Direct docking supported
|
|
E3L009923
BDB009923
|
BDBM215443
CC[C@H]1[C@H](C)O[C@]23OC(=O)C[C@@]2(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N13
|
C25H27Cl2NO3 460.401000 |
PJVZSNYUBWTHII-JINHIYLYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215443; PubChem:CID58573938
|
Local ready
Direct docking supported
|
|
E3L009924
BDB009924
|
BDBM215444
CC[C@@H]([C@H](C)O)N1C(=O)[C@@](C)(C[C@H](O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H33Cl2NO4 494.459000 |
KROAAONPLZABTR-YSILZPMOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215444; PubChem:CID58573685
|
Local ready
Direct docking supported
|
|
E3L009925
BDB009925
|
BDBM215445
CC[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CS(C)(=O)=O)C2CC2)C1=O
|
C27H31Cl2NO5S 552.520000 |
NYMRMAMSVZGJIB-JTOATPROSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215445; PubChem:CID67999982
|
Local ready
Direct docking supported
|
|
E3L009926
BDB009926
|
BDBM215704
CCc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O2 523.559000 |
AOGSTLSIDHPPIC-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215704; PubChem:CID90320097
|
Local ready
Direct docking supported
|
|
E3L009927
BDB009927
|
BDBM215705
CC(C)c1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O2 537.586000 |
KZMKXOYMNUFFOB-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215705; PubChem:CID90325537
|
Local ready
Direct docking supported
|
|
E3L009928
BDB009928
|
BDBM215706
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C(C)(C)C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H32F3N5O2 551.613000 |
OJMZUDMDAGZKCZ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215706; PubChem:CID90317667
|
Local ready
Direct docking supported
|
|
E3L009929
BDB009929
|
BDBM215707
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(OC(F)(F)F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H21F6N5O3 565.474000 |
IAWUWYQLIKFWHZ-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215707; PubChem:CID90318189
|
Local ready
Direct docking supported
|
|
E3L009930
BDB009930
|
BDBM215708
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(OC(F)(F)F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H21F6N5O3 565.474000 |
WEQDKBVODOUEQU-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215708; PubChem:CID90325538
|
Local ready
Direct docking supported
|
|
E3L009931
BDB009931
|
BDBM215709
COc1cc(OC)cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H26F3N5O4 541.530000 |
JZFCMFMOYMYTEC-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215709; PubChem:CID90325541
|
Local ready
Direct docking supported
|
|
E3L009932
BDB009932
|
BDBM215710
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(N(C)C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C27H27F3N6O2 524.547000 |
IBYUTYVUOIDHJR-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215710; PubChem:CID90325536
|
Local ready
Direct docking supported
|
|
E3L009933
BDB009933
|
BDBM215711
Cc1ccccc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C26H24F3N5O2 495.505000 |
YJAFFHMPSWFHMH-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215711; PubChem:CID90319809
|
Local ready
Direct docking supported
|
|
E3L009934
BDB009934
|
BDBM215712
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Cl)c(Cl)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H20Cl2F3N5O2 550.368000 |
LADMSJRXUWIXMN-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215712; PubChem:CID90325358
|
Local ready
Direct docking supported
|
|
E3L009935
BDB009935
|
BDBM215713
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C(C)(C)C)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C29H30F3N5O2 537.586000 |
WVBROTXJHAPVBO-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215713; PubChem:CID90319828
|
Local ready
Direct docking supported
|
|
E3L009936
BDB009936
|
BDBM215759
Cc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1
|
C26H24F3N5O2 495.505000 |
QYWXKUGUIGBCKS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215759; PubChem:CID90320103
|
Local ready
Direct docking supported
|
|
E3L009937
BDB009937
|
BDBM215784
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3OC(F)(F)F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H21F6N5O3 565.474000 |
RRWULIZUMHFANF-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215784; PubChem:CID90318437
|
Local ready
Direct docking supported
|
|
E3L009938
BDB009938
|
BDBM215785
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cnn(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C23H22F3N7O2 485.470000 |
YKVGBIKGLZEWTF-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215785; PubChem:CID90320216
|
Local ready
Direct docking supported
|
|
E3L009939
BDB009939
|
BDBM215786
Cc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cn1
|
C25H23F3N6O2 496.493000 |
LJTPFXSGVFGOMX-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215786; PubChem:CID90325355
|
Local ready
Direct docking supported
|
|
E3L009940
BDB009940
|
BDBM215791
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(N(C)C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O2 538.574000 |
JVPMJCQDRCZMIC-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215791; PubChem:CID90325615
|
Local ready
Direct docking supported
|