| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009941
BDB009941
|
BDBM217401
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(OC(F)(F)F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H23F6N5O3 579.501000 |
ALPBIIQVJXBXLR-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM217401; PubChem:CID90325602
|
Local ready
Direct docking supported
|
|
E3L009942
BDB009942
|
BDBM217705
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(Cl)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H23ClF3N5O2 529.950000 |
AEMXGOGKHPPBEX-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM217705; PubChem:CID90317925
|
Local ready
Direct docking supported
|
|
E3L009943
BDB009943
|
BDBM218079
CNS(=O)(=O)c1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1
|
C27H27F3N6O4S 588.612000 |
ZEPRPCRZIHKHIM-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218079; PubChem:CID90325608
|
Local ready
Direct docking supported
|
|
E3L009944
BDB009944
|
BDBM218160
C[C@@H](Nc1nc(C(=O)O)nc2nc(C3CC3)n(Cc3ccc(Cl)cc3)c12)C1CC1
|
C21H22ClN5O2 411.893000 |
XKCGIYVXMLRHKC-LLVKDONJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218160; PubChem:CID90318613
|
Local ready
Direct docking supported
|
|
E3L009945
BDB009945
|
BDBM218162
C[C@@H](Nc1nc(C(=O)O)nc2nc(Cc3ccccc3)n(Cc3ccc(Cl)cc3)c12)C1CC1
|
C25H24ClN5O2 461.953000 |
VEIPAQPJILLOFQ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218162; PubChem:CID90325622
|
Local ready
Direct docking supported
|
|
E3L009946
BDB009946
|
BDBM218164
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccnc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C24H21F3N6O2 482.466000 |
RKRWOWGPKFRJMI-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218164; PubChem:CID90318352
|
Local ready
Direct docking supported
|
|
E3L009947
BDB009947
|
BDBM218166
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C#N)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H23F3N6O2 520.515000 |
IASOJHYJWBXPBG-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218166; PubChem:CID90317947
|
Local ready
Direct docking supported
|
|
E3L009948
BDB009948
|
BDBM218168
COc1ncc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1Cl
|
C26H24ClF3N6O3 560.964000 |
MJKCISDZMIVLIU-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218168; PubChem:CID90318696
|
Local ready
Direct docking supported
|
|
E3L009949
BDB009949
|
BDBM218170
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H23F4N5O2 513.495000 |
BQNNVBZSNMKHAO-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218170; PubChem:CID90320129
|
Local ready
Direct docking supported
|
|
E3L009950
BDB009950
|
BDBM218172
COc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cn1
|
C25H23F3N6O3 512.492000 |
NVCGYIRUNVBTOK-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218172; PubChem:CID90317875
|
Local ready
Direct docking supported
|
|
E3L009951
BDB009951
|
BDBM218173
COc1ncc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1F
|
C25H22F4N6O3 530.482000 |
QNNJYCJRYBCPKZ-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218173; PubChem:CID90324934
|
Local ready
Direct docking supported
|
|
E3L009952
BDB009952
|
BDBM218175
Cc1cc(C)cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H26F3N5O2 509.532000 |
GTOQPQCHQVOWER-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218175; PubChem:CID90324937
|
Local ready
Direct docking supported
|
|
E3L009953
BDB009953
|
BDBM218177
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cnc(O)c(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C24H20F4N6O3 516.455000 |
ZVSXZGZCKPSWLV-LLVKDONJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218177; PubChem:CID136632586
|
Local ready
Direct docking supported
|
|
E3L009954
BDB009954
|
BDBM218181
Cc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c(C)c1
|
C27H26F3N5O2 509.532000 |
RCFCOTFGDQKXKQ-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218181; PubChem:CID90325013
|
Local ready
Direct docking supported
|
|
E3L009955
BDB009955
|
BDBM218182
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Cl)c(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H20ClF4N5O2 533.913000 |
SKONRKCGMNTWQP-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218182; PubChem:CID90317605
|
Local ready
Direct docking supported
|
|
E3L009956
BDB009956
|
BDBM218183
Cc1cc(OC(F)(F)F)ccc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H23F6N5O3 579.501000 |
WPFSSWCWAJYODW-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218183; PubChem:CID90325020
|
Local ready
Direct docking supported
|
|
E3L009957
BDB009957
|
BDBM218185
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3Cl)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H21ClF3N5O2 515.923000 |
BOZHRJGOBLIKLC-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218185; PubChem:CID90325017
|
Local ready
Direct docking supported
|
|
E3L009958
BDB009958
|
BDBM218186
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H21F4N5O2 499.468000 |
VRJDSVOPJWYNGV-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218186; PubChem:CID90317545
|
Local ready
Direct docking supported
|
|
E3L009959
BDB009959
|
BDBM218188
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C#N)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H21F3N6O2 506.488000 |
GUXVFSWBHXITDQ-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218188; PubChem:CID90325018
|
Local ready
Direct docking supported
|
|
E3L009960
BDB009960
|
BDBM218190
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Cl)cc3Cl)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H20Cl2F3N5O2 550.368000 |
YXGLEOQIMHVVQB-GFCCVEGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM218190; PubChem:CID90324952
|
Local ready
Direct docking supported
|