| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L009901
BDB009901
|
BDBM215420
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCOCC2)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H43Cl2N3O6S 680.695000 |
ZWUXHCHNAJMQDB-ZONMCSLISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM215420
|
Local ready
Direct docking supported
|
|
E3L009902
BDB009902
|
BDBM215421
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C(F)(F)F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C26H21F6N5O2 549.475000 |
PELHYRKFKXYVLP-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215421; PubChem:CID90318774
|
Local ready
Direct docking supported
|
|
E3L009903
BDB009903
|
BDBM215422
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCCC2)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H43Cl2N3O5S 664.696000 |
VXJACAQXCDSPJE-ZONMCSLISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM215422
|
Local ready
Direct docking supported
|
|
E3L009904
BDB009904
|
BDBM215423
COc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1
|
C26H24F3N5O3 511.504000 |
VUPIFPKELFOASH-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215423; PubChem:CID90319829
|
Local ready
Direct docking supported
|
|
E3L009905
BDB009905
|
BDBM215424
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(Cl)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CC1
|
C25H21ClF3N5O2 515.923000 |
OIARBJDAZGEJNF-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215424; PubChem:CID90325014
|
Local ready
Direct docking supported
|
|
E3L009906
BDB009906
|
BDBM215425
CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](CCN2CCS(=O)(=O)CC2)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H44Cl2N4O6S2 727.777000 |
FIHLYTVROCTNSC-XPOFXAFUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM215425
|
Local ready
Direct docking supported
|
|
E3L009907
BDB009907
|
BDBM215426
CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@]2(C[C@H](c3cccc(Cl)c3)C1c1ccc(Cl)cc1)C[C@H]2C(=O)O
|
C28H32Cl2N2O5S 579.546000 |
NYKRRIQBYZLKHH-ZCBDLFDQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215426; PubChem:CID117656799
|
Local ready
Direct docking supported
|
|
E3L009908
BDB009908
|
BDBM215427
CC[C@@H]([C@H](O)CO)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H29Cl2NO5 494.415000 |
COYWEWWEQVRWQE-FIXGDMNTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215427; PubChem:CID58573577
|
Local ready
Direct docking supported
|
|
E3L009909
BDB009909
|
BDBM215429
CC[C@@H]([C@H](O)C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H31Cl2NO4 504.454000 |
PHSMLYLJCQVUSJ-OPYPCFFTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215429; PubChem:CID58573823
|
Local ready
Direct docking supported
|
|
E3L009910
BDB009910
|
BDBM215430
CC(C)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@]1(C)c1ccc(Cl)cc1
|
C23H25Cl2NO3 434.363000 |
LQRDMEGRDDOARK-LERMDLETSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215430; PubChem:CID58573494
|
Local ready
Direct docking supported
|
|
E3L009911
BDB009911
|
BDBM215431
CC(C)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@]1(C)c1ccc(Cl)cc1
|
C23H25Cl2NO3 434.363000 |
LQRDMEGRDDOARK-AYPBNUJASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215431; PubChem:CID58573825
|
Local ready
Direct docking supported
|
|
E3L009912
BDB009912
|
BDBM215432
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@H](Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H35Cl2N3O4S 616.611000 |
LXGSJAGQGNYLQC-WUIMFCPGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215432; PubChem:CID58573946
|
Local ready
Direct docking supported
|
|
E3L009913
BDB009913
|
BDBM215433
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@H](Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H35Cl2N3O4S 616.611000 |
LXGSJAGQGNYLQC-MWZYUOISSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215433; PubChem:CID58573681
|
Local ready
Direct docking supported
|
|
E3L009914
BDB009914
|
BDBM215434
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@H](Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C30H33Cl2N3O4S 602.584000 |
PNCDGXOHOAFJKW-IXSCWARWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215434; PubChem:CID58573761
|
Local ready
Direct docking supported
|
|
E3L009915
BDB009915
|
BDBM215435
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@H](Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C30H33Cl2N3O4S 602.584000 |
PNCDGXOHOAFJKW-DTIFBSDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215435; PubChem:CID58573545
|
Local ready
Direct docking supported
|
|
E3L009916
BDB009916
|
BDBM215436
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@](C)(Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C32H37Cl2N3O4S 630.638000 |
SVUVOAAWIIGAGC-QBIAMMSFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215436; PubChem:CID58573784
|
Local ready
Direct docking supported
|
|
E3L009917
BDB009917
|
BDBM215437
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(Cc2cccc(OC)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C32H37Cl2N3O4S 630.638000 |
SVUVOAAWIIGAGC-MORJLMJXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215437; PubChem:CID58574010
|
Local ready
Direct docking supported
|
|
E3L009918
BDB009918
|
BDBM215438
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@](C)(Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H35Cl2N3O4S 616.611000 |
JALVLPROXFDZPY-DGEPZWHSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215438; PubChem:CID58573910
|
Local ready
Direct docking supported
|
|
E3L009919
BDB009919
|
BDBM215439
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(Cc2cccc(O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C31H35Cl2N3O4S 616.611000 |
JALVLPROXFDZPY-SDSXRCECSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215439; PubChem:CID58573861
|
Local ready
Direct docking supported
|
|
E3L009920
BDB009920
|
BDBM215440
CCS(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H33Cl2NO5S 566.547000 |
SDVTVXLQMGTUDI-LHWXFDGDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM215440; PubChem:CID68000688
|
Local ready
Direct docking supported
|