| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010221
BDB010221
|
BDBM221855
Cc1noc(C2CCCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n1
|
C29H31F3N10O3 624.628000 |
CILBZRHONDAZJD-IWPPFLRJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM221855
|
Local ready
Direct docking supported
|
|
E3L010222
BDB010222
|
BDBM221861
CC(C)CN1CCC(CN(C)c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)C1
|
C31H40F3N9O2 627.716000 |
NQSGEHXNIZUZRD-YMBRHYMPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM221861
|
Local ready
Direct docking supported
|
|
E3L010223
BDB010223
|
BDBM221936
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC3Cc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C33H35F3N8O2 632.691000 |
QTPPHPDCTFPXLR-VGOKPJQXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221936; PubChem:CID136632703
|
Local ready
Direct docking supported
|
|
E3L010224
BDB010224
|
BDBM221937
CC1CCCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H31F3N8O2 556.593000 |
TURYGLHWIYEEIC-OEMAIJDKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221937; PubChem:CID136632661
|
Local ready
Direct docking supported
|
|
E3L010225
BDB010225
|
BDBM221938
COCC1CCCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H33F3N8O3 586.619000 |
ZLXHZIKHCWOVHZ-QRIPLOBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221938; PubChem:CID136632467
|
Local ready
Direct docking supported
|
|
E3L010226
BDB010226
|
BDBM221940
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC3c3ccc(F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H32F4N8O2 636.654000 |
XBCUPPXCDFRXBY-QFADGXAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221940; PubChem:CID136632374
|
Local ready
Direct docking supported
|
|
E3L010227
BDB010227
|
BDBM221943
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC3c3cccc(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H32F4N8O2 636.654000 |
VFFCSWXRSIICQY-QFADGXAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221943; PubChem:CID136632664
|
Local ready
Direct docking supported
|
|
E3L010228
BDB010228
|
BDBM221945
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3cccnc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H32F3N7O2 579.627000 |
GZCSZKVEPLMADG-FKSKYRLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221945; PubChem:CID90318455
|
Local ready
Direct docking supported
|
|
E3L010229
BDB010229
|
BDBM221947
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccncc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H32F3N7O2 579.627000 |
QYMMJTNISYEKQJ-FKSKYRLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221947; PubChem:CID90317670
|
Local ready
Direct docking supported
|
|
E3L010230
BDB010230
|
BDBM221948
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3cccc(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H32F4N6O2 596.629000 |
UPSSNKTUFWZVBS-QFADGXAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221948; PubChem:CID90325488
|
Local ready
Direct docking supported
|
|
E3L010231
BDB010231
|
BDBM221950
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccc(F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H32F4N6O2 596.629000 |
MIHNEHWSSVGUME-QFADGXAASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221950; PubChem:CID90325495
|
Local ready
Direct docking supported
|
|
E3L010232
BDB010232
|
BDBM221951
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C24H27F3N6O3 504.513000 |
NENNZWIEFIDDIG-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221951; PubChem:CID90325492
|
Local ready
Direct docking supported
|
|
E3L010233
BDB010233
|
BDBM221953
CC(C)C1CCCCN1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H35F3N6O2 544.622000 |
PSIKMBMRWIOCMC-OQHSHRKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221953; PubChem:CID90325489
|
Local ready
Direct docking supported
|
|
E3L010234
BDB010234
|
BDBM221954
CC(C)CC1CCCCN1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H37F3N6O2 558.649000 |
UAAROQBTHHTVTJ-ZZWBGTBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221954; PubChem:CID90325493
|
Local ready
Direct docking supported
|
|
E3L010235
BDB010235
|
BDBM221956
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCc4ccccc4C3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O2 550.585000 |
GEDSSRIJJBOTMT-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221956; PubChem:CID90318398
|
Local ready
Direct docking supported
|
|
E3L010236
BDB010236
|
BDBM221957
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3C3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H39F3N6O2 584.687000 |
JWECQCAULNQNNM-PHSANKKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221957; PubChem:CID90318031
|
Local ready
Direct docking supported
|
|
E3L010237
BDB010237
|
BDBM221959
C[C@@H](Nc1nc(C(=O)O)nc2nc(NC(C)(C)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
SHZZOIQPOMJHMT-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221959; PubChem:CID90325005
|
Local ready
Direct docking supported
|
|
E3L010238
BDB010238
|
BDBM221960
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCc4ccccc43)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O2 550.585000 |
ZBTNYDPALYPPJS-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221960; PubChem:CID90318443
|
Local ready
Direct docking supported
|
|
E3L010239
BDB010239
|
BDBM221961
C[C@@H]1COCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C26H29F3N8O3 558.565000 |
QJZXEXAMYCFNEO-HUUCEWRRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221961; PubChem:CID136632585
|
Local ready
Direct docking supported
|
|
E3L010240
BDB010240
|
BDBM221963
C[C@@H](Nc1nc(C(=O)O)nc2nc(COc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H26F3N5O3 525.531000 |
XIJNWLQXBQBIQX-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221963; PubChem:CID90320003
|
Local ready
Direct docking supported
|