| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010441
BDB010441
|
BDBM223749
C[C@@H](Nc1nc(-c2nnn(C)n2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H42N10O 570.746000 |
ICSCNDATZFOZRC-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223749
|
Local ready
Direct docking supported
|
|
E3L010442
BDB010442
|
BDBM223750
C[C@@H](Nc1nc(-c2nnnn2C)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H42N10O 570.746000 |
VWGUMYMEYOHSTG-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223750
|
Local ready
Direct docking supported
|
|
E3L010443
BDB010443
|
BDBM223751
COC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(N1CCOC[C@H]1c1ccccc1)n2C[C@H]1CC[C@H](C)CC1
|
C31H42N6O3 546.716000 |
ANFUAKMPMGMGNB-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223751
|
Local ready
Direct docking supported
|
|
E3L010444
BDB010444
|
BDBM223752
C[C@@H](Nc1nc(C(C)(C)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H46N6O2 546.760000 |
SPWNJLXALPVZGR-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223752
|
Local ready
Direct docking supported
|
|
E3L010445
BDB010445
|
BDBM223753
C[C@@H](Nc1nc(-c2n[nH]c(=O)n2C)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H43N9O2 585.757000 |
NRPYAIXVOJBLTQ-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223753
|
Local ready
Direct docking supported
|
|
E3L010446
BDB010446
|
BDBM223754
C[C@@H](Nc1nc(-c2nnc[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H41N9O 555.731000 |
RKGWXBUXXFDHQT-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223754
|
Local ready
Direct docking supported
|
|
E3L010447
BDB010447
|
BDBM223755
CCNC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(N1CCOC[C@H]1c1ccccc1)n2C[C@H]1CC[C@H](C)CC1
|
C32H45N7O2 559.759000 |
UTSRINWUWZAGTP-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223755
|
Local ready
Direct docking supported
|
|
E3L010448
BDB010448
|
BDBM223756
C[C@@H](Nc1nc(C(=O)NS(C)(=O)=O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H43N7O4S 609.797000 |
FNSNMYKRBJIYPZ-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223756
|
Local ready
Direct docking supported
|
|
E3L010449
BDB010449
|
BDBM223757
C[C@@H](Nc1nc(-c2nc(=O)n(C)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H43N9O2 585.757000 |
PSQIQIKLIJXJIY-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223757
|
Local ready
Direct docking supported
|
|
E3L010450
BDB010450
|
BDBM223758
C[C@@H](Nc1nc(C(O)CO)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H44N6O3 548.732000 |
VTVLEDOTHDKDQM-YBCQIOIQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223758
|
Local ready
Direct docking supported
|
|
E3L010451
BDB010451
|
BDBM223759
CC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(N1CCOC[C@H]1c1ccccc1)n2C[C@H]1CC[C@H](C)CC1
|
C31H42N6O2 530.717000 |
IDPXRIFCZDEIPJ-YNMPZUNCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223759
|
Local ready
Direct docking supported
|
|
E3L010452
BDB010452
|
BDBM223760
C[C@@H](Nc1nc(CO)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H42N6O2 518.706000 |
ARWDACNKKUQBGN-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223760
|
Local ready
Direct docking supported
|
|
E3L010453
BDB010453
|
BDBM223762
C[C@@H](Nc1nc(C(=O)NS(=O)(=O)N(C)C)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H46N8O4S 638.839000 |
SKCAXUQVQMLKOO-FCBCXNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223762
|
Local ready
Direct docking supported
|
|
E3L010454
BDB010454
|
BDBM223763
Cc1cccc(-c2nc3nc(C(=O)NS(C)(=O)=O)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H27F3N6O3S 572.613000 |
VYKKSZIIZBZKCR-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223763; PubChem:CID118558532
|
Local ready
Direct docking supported
|
|
E3L010455
BDB010455
|
BDBM223764
Cc1cccc(-c2nc3nc(-c4nnn[nH]4)nc(N[C@H](C)C4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H24F3N9 519.535000 |
ZEANAHQYKPPMMX-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223764; PubChem:CID90325572
|
Local ready
Direct docking supported
|
|
E3L010456
BDB010456
|
BDBM223765
Cc1cccc(-c2nc3nc(C(N)=O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H27F3N6O 508.548000 |
BOSNYGLXXFHKTO-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223765; PubChem:CID90325099
|
Local ready
Direct docking supported
|
|
E3L010457
BDB010457
|
BDBM223766
Cc1cccc(-c2nc3nc(-c4nc[nH]n4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H27F3N8 532.574000 |
SMHYTDXAEJMOCR-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223766; PubChem:CID118566489
|
Local ready
Direct docking supported
|
|
E3L010458
BDB010458
|
BDBM223768
CNC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1cccc(C)c1)n2Cc1ccc(C(F)(F)F)cc1
|
C28H29F3N6O 522.575000 |
GNOZZDKPMHCBEM-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223768; PubChem:CID90325100
|
Local ready
Direct docking supported
|
|
E3L010459
BDB010459
|
BDBM223769
Cc1cc(C)cc(-c2nc3nc(C(N)=O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H29F3N6O 522.575000 |
ZFGZQRFEHLMIAH-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223769; PubChem:CID118566490
|
Local ready
Direct docking supported
|
|
E3L010460
BDB010460
|
BDBM223770
CONC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1cc(C(C)C)ccn1)n2Cc1ccc(C(F)(F)F)cc1
|
C29H32F3N7O2 567.616000 |
JIXONLGOLPIQBO-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223770; PubChem:CID90325102
|
Local ready
Direct docking supported
|