| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010421
BDB010421
|
BDBM223724
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CC4CC4C3C(F)(F)F)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H35F3N8O2 560.625000 |
MHBDJEPLDLOFGL-CEULFALRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223724
|
Local ready
Direct docking supported
|
|
E3L010422
BDB010422
|
BDBM223725
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCC3CS(C)(=O)=O)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H40N8O4S 572.736000 |
HVMDGNTUUAEEKG-KYJJNMIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223725
|
Local ready
Direct docking supported
|
|
E3L010423
BDB010423
|
BDBM223726
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCC3C[S+](C)[O-])n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H40N8O3S 556.737000 |
OWXDCGGGZOXQDM-LEEXENQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223726
|
Local ready
Direct docking supported
|
|
E3L010424
BDB010424
|
BDBM223728
CC1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1C
|
C27H40N8O3 524.670000 |
PHWMILWUUXEUGX-XBBDAYDNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223728
|
Local ready
Direct docking supported
|
|
E3L010425
BDB010425
|
BDBM223730
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC4CCCCC43)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H42N8O3 550.708000 |
VUJCELGYCZVQEI-FDNSPFKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223730
|
Local ready
Direct docking supported
|
|
E3L010426
BDB010426
|
BDBM223732
C[C@@H](Nc1nc(-c2n[nH]c(=O)o2)nc2nc(N3CCOC4CCCCC43)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H42N8O3 550.708000 |
PEXHJBUQRMZUIW-FDNSPFKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223732
|
Local ready
Direct docking supported
|
|
E3L010427
BDB010427
|
BDBM223734
C[C@@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H42N8O3 586.741000 |
ONZOHYSBOCAUJY-ILJOYBHNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223734
|
Local ready
Direct docking supported
|
|
E3L010428
BDB010428
|
BDBM223735
C[C@@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H42N8O3 586.741000 |
UWAKLLBUNDYNJV-ILJOYBHNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223735
|
Local ready
Direct docking supported
|
|
E3L010429
BDB010429
|
BDBM223736
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCO[C@H](C)[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H42N8O3 586.741000 |
ONZOHYSBOCAUJY-CITZFPKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223736
|
Local ready
Direct docking supported
|
|
E3L010430
BDB010430
|
BDBM223737
C[C@@H](Nc1nc(-c2n[nH]c(=O)o2)nc2nc(N3CCO[C@H](C)[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H42N8O3 586.741000 |
UWAKLLBUNDYNJV-CITZFPKPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223737
|
Local ready
Direct docking supported
|
|
E3L010431
BDB010431
|
BDBM223739
CC(C)c1ccnc(-c2nc3nc(-c4nnn[nH]4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H29F3N10 562.604000 |
GWQGUFHYQLCSBC-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223739; PubChem:CID90325282
|
Local ready
Direct docking supported
|
|
E3L010432
BDB010432
|
BDBM223740
CC(C)c1ccnc(-c2nc3nc(CO)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H31F3N6O 524.591000 |
UTJKAWNHWMWUAV-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223740; PubChem:CID90325302
|
Local ready
Direct docking supported
|
|
E3L010433
BDB010433
|
BDBM223741
CC(C)c1ccnc(-c2nc3nc(-c4cnn[nH]4)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N9 561.616000 |
QAFZSXXBWUTEHY-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM223741; PubChem:CID90325090
|
Local ready
Direct docking supported
|
|
E3L010434
BDB010434
|
BDBM223742
CC(C)c1ccnc(-c2nc3nc(CN)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C28H41N7 475.685000 |
JDRTVFGRGIYGGU-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223742
|
Local ready
Direct docking supported
|
|
E3L010435
BDB010435
|
BDBM223743
CC(=O)c1nc(N[C@H](C)C2CCC2)c2c(n1)nc(-c1cc(C(C)C)ccn1)n2C[C@H]1CC[C@H](C)CC1
|
C29H40N6O 488.680000 |
HMOHRHDMBGJWKS-SFHLNBCPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223743
|
Local ready
Direct docking supported
|
|
E3L010436
BDB010436
|
BDBM223744
CC(C)c1ccnc(-c2nc3nc(C(C)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C29H42N6O 490.696000 |
BIEZPXUZUSQRET-WLSJHPEUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223744
|
Local ready
Direct docking supported
|
|
E3L010437
BDB010437
|
BDBM223745
CC(C)c1ccnc(-c2nc3nc(C(C)(C)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C30H44N6O 504.723000 |
WOUPZKNNDVGPBQ-NJDAHSKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223745
|
Local ready
Direct docking supported
|
|
E3L010438
BDB010438
|
BDBM223746
CC(C)c1ccnc(-c2nc3nc(-c4nnn[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C28H38N10 514.682000 |
NBXONUCFOYIQCU-GUDVDZBRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223746
|
Local ready
Direct docking supported
|
|
E3L010439
BDB010439
|
BDBM223747
CC(C)c1ccnc(-c2nc3nc(CNS(C)(=O)=O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C29H43N7O2S 553.777000 |
CNBCATNFQQQCLU-NJDAHSKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223747
|
Local ready
Direct docking supported
|
|
E3L010440
BDB010440
|
BDBM223748
CC(C)c1ccnc(-c2nc3nc(CNC(=O)C(F)(F)F)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C30H40F3N7O 571.692000 |
RUNFCNCXSPUBIA-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223748
|
Local ready
Direct docking supported
|