| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010381
BDB010381
|
BDBM223668
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3C4CCC3COC4)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H38N8O3 522.654000 |
XATKFXLJUCVYGI-PQLJQCGPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223668
|
Local ready
Direct docking supported
|
|
E3L010382
BDB010382
|
BDBM223669
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC4CCCCC43)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H42N8O3 550.708000 |
VUJCELGYCZVQEI-FDNSPFKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223669
|
Local ready
Direct docking supported
|
|
E3L010383
BDB010383
|
BDBM223671
C[C@@H]1COCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H38N8O3 510.643000 |
XLTQUABIIGUOGB-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223671
|
Local ready
Direct docking supported
|
|
E3L010384
BDB010384
|
BDBM223672
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOCC3(C)C)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H40N8O3 524.670000 |
WFVCUCOJDBBSCV-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223672
|
Local ready
Direct docking supported
|
|
E3L010385
BDB010385
|
BDBM223673
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOCC3c3ccc(Cl)cc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H39ClN8O3 607.159000 |
CEUPRVKOJHAQPA-JETLDYTISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223673
|
Local ready
Direct docking supported
|
|
E3L010386
BDB010386
|
BDBM223674
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOCC3c3ccccc3Cl)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H39ClN8O3 607.159000 |
ZZHDLJFSHPIGKM-JETLDYTISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223674
|
Local ready
Direct docking supported
|
|
E3L010387
BDB010387
|
BDBM223675
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3Cc3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H42N8O3 586.741000 |
PIHCUDJBAUXVAH-AFFJLAOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223675
|
Local ready
Direct docking supported
|
|
E3L010388
BDB010388
|
BDBM223676
COC1(C)CN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C26H38N8O3 510.643000 |
PJONEHGJQCXVFK-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223676
|
Local ready
Direct docking supported
|
|
E3L010389
BDB010389
|
BDBM223677
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CC(C)(O)C3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C25H36N8O3 496.616000 |
FHJYNRCXPRNWEQ-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223677
|
Local ready
Direct docking supported
|
|
E3L010390
BDB010390
|
BDBM223678
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOCC(F)(F)C3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H36F2N8O3 546.623000 |
GMGQZACESLHAKJ-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223678
|
Local ready
Direct docking supported
|
|
E3L010391
BDB010391
|
BDBM223679
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCOCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H38N8O3 510.643000 |
HKEIBRLCNBQNDD-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223679
|
Local ready
Direct docking supported
|
|
E3L010392
BDB010392
|
BDBM223680
C[C@H](Nc1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1)c1cccc(F)c1
|
C29H37FN8O2 548.667000 |
UWHDFCPPEXYFPZ-AKHDSKFASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223680
|
Local ready
Direct docking supported
|
|
E3L010393
BDB010393
|
BDBM223681
COC(C)(C)C1CCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H44N8O3 552.724000 |
RPEXSQZXYWFONN-OCQFDOBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223681
|
Local ready
Direct docking supported
|
|
E3L010394
BDB010394
|
BDBM223682
Cc1nonc1C1CCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H38N10O3 562.679000 |
WREYPPBWYYQFAW-UWOBQLFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223682
|
Local ready
Direct docking supported
|
|
E3L010395
BDB010395
|
BDBM223683
Cc1nn(C)cc1CNc1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H38N10O2 534.669000 |
YXHPFBZZJIENAF-JFIYKMOQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223683
|
Local ready
Direct docking supported
|
|
E3L010396
BDB010396
|
BDBM223684
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCC[C@H]3c3nnnn3C)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H38N12O2 562.683000 |
NEVIUMRHVHPVKF-MTNOOBJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223684
|
Local ready
Direct docking supported
|
|
E3L010397
BDB010397
|
BDBM223685
Cc1nonc1CNc1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H34N10O3 522.614000 |
ZSZDXRRKSAHSOI-IIAWOOMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223685
|
Local ready
Direct docking supported
|
|
E3L010398
BDB010398
|
BDBM223686
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(NCc3c[nH]nc3-c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H38N10O2 582.713000 |
NQGWZFGMLMNTRU-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223686
|
Local ready
Direct docking supported
|
|
E3L010399
BDB010399
|
BDBM223687
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCC(C)(O)C3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H38N8O3 510.643000 |
PQJDKCOFKGMUCR-WZEHMONGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223687
|
Local ready
Direct docking supported
|
|
E3L010400
BDB010400
|
BDBM223688
COC1CCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C26H38N8O3 510.643000 |
IIIHZYOKMPGCGI-YIVKDGLNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223688
|
Local ready
Direct docking supported
|