| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010601
BDB010601
|
BDBM224171
C[C@H]1CC[C@H](Cn2c(N3CCO[C@@H]4CCC[C@H]43)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H31ClN8O3 551.051000 |
BWIXNPIRFHSINV-XNFNUYLZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224171
|
Local ready
Direct docking supported
|
|
E3L010602
BDB010602
|
BDBM224172
C[C@H]1CC[C@H](Cn2c(N3CCO[C@H]4CCC[C@@H]43)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H31ClN8O3 551.051000 |
BWIXNPIRFHSINV-FVCZOJIISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224172
|
Local ready
Direct docking supported
|
|
E3L010603
BDB010603
|
BDBM224173
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3F)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H30ClFN8O3 605.074000 |
QYVNXAFKFKTATQ-BSRJHKFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224173
|
Local ready
Direct docking supported
|
|
E3L010604
BDB010604
|
BDBM224174
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccc(F)cc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H30ClFN8O3 605.074000 |
WDWBHDBIVDGXKO-BSRJHKFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224174
|
Local ready
Direct docking supported
|
|
E3L010605
BDB010605
|
BDBM224175
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccc(F)cc3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H30ClFN8O3 605.074000 |
VLBSTDJCUZXJIK-BSRJHKFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224175
|
Local ready
Direct docking supported
|
|
E3L010606
BDB010606
|
BDBM224176
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3F)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C30H30ClFN8O3 605.074000 |
DTYALZUJQWKTIE-BSRJHKFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224176
|
Local ready
Direct docking supported
|
|
E3L010607
BDB010607
|
BDBM224177
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccncc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
MCOMVBZDKSRHFC-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224177
|
Local ready
Direct docking supported
|
|
E3L010608
BDB010608
|
BDBM224178
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccncc3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
HPKDSOXQEGISMF-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224178
|
Local ready
Direct docking supported
|
|
E3L010609
BDB010609
|
BDBM224179
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccn3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
ZAKIJICUSPKJMR-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224179
|
Local ready
Direct docking supported
|
|
E3L010610
BDB010610
|
BDBM224180
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccn3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
NQFLMPQKNSJXIH-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224180
|
Local ready
Direct docking supported
|
|
E3L010611
BDB010611
|
BDBM224181
C[C@@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1C
|
C27H32ClN7O3 538.052000 |
GIXREIKFDOITDO-ZJPYXAASSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224181
|
Local ready
Direct docking supported
|
|
E3L010612
BDB010612
|
BDBM224182
C[C@@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1C
|
C27H32ClN7O3 538.052000 |
UBCUYTNZLHUSTK-ZJPYXAASSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224182
|
Local ready
Direct docking supported
|
|
E3L010613
BDB010613
|
BDBM224183
C[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H32ClN7O3 538.052000 |
GIXREIKFDOITDO-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224183
|
Local ready
Direct docking supported
|
|
E3L010614
BDB010614
|
BDBM224184
C[C@@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1C
|
C26H31ClN8O3 539.040000 |
VOXJMEPEQFUQDQ-WCXIOVBPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224184
|
Local ready
Direct docking supported
|
|
E3L010615
BDB010615
|
BDBM224185
C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3CF)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H28ClFN8O2 527.004000 |
AEIDQACKNYJVQK-MPGHIAIKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224185
|
Local ready
Direct docking supported
|
|
E3L010616
BDB010616
|
BDBM224186
C[C@@H]1COC[C@@H](C)N1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN8O3 539.040000 |
OWCNBKAWTYPOAT-QBPKDAKJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224186
|
Local ready
Direct docking supported
|
|
E3L010617
BDB010617
|
BDBM224187
C[C@H]1CC[C@H](Cn2c(N3CCC[C@H]3C(F)(F)F)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H26ClF3N8O2 562.984000 |
YEYWUOMQAGHDDS-ZQIUZPCESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224187
|
Local ready
Direct docking supported
|
|
E3L010618
BDB010618
|
BDBM224188
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)nc(Cl)c4)c32)CC1
|
C30H30Cl2N8O3 621.529000 |
QUFJEQKVDAQSNV-WFXMLNOXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224188
|
Local ready
Direct docking supported
|
|
E3L010619
BDB010619
|
BDBM224189
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cnc4F)c32)CC1
|
C30H30ClFN8O3 605.074000 |
XFXZDZCWQPLTCQ-SPEDKVCISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224189
|
Local ready
Direct docking supported
|
|
E3L010620
BDB010620
|
BDBM224190
COc1cc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)cc(Cl)n1
|
C31H33ClN8O4 617.110000 |
OQDHTFYRFYIKOO-IPJJNNNSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224190
|
Local ready
Direct docking supported
|