| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010641
BDB010641
|
BDBM224213
C[C@@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H34ClN7O3 600.123000 |
UXFYSVQWWYMTNL-JYEBCORGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224213
|
Local ready
Direct docking supported
|
|
E3L010642
BDB010642
|
BDBM224214
C[C@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C31H33ClN8O3 601.111000 |
MNFALKSWLMSBID-YASKCIBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224214
|
Local ready
Direct docking supported
|
|
E3L010643
BDB010643
|
BDBM224215
C[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H32ClN7O3 538.052000 |
UBCUYTNZLHUSTK-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224215
|
Local ready
Direct docking supported
|
|
E3L010644
BDB010644
|
BDBM224216
C[C@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C31H33ClN8O3 601.111000 |
BQYKCUJMTWHUEF-YASKCIBGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224216
|
Local ready
Direct docking supported
|
|
E3L010645
BDB010645
|
BDBM224217
C[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN8O3 539.040000 |
QFYGZZMETSMPSS-QBPKDAKJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224217
|
Local ready
Direct docking supported
|
|
E3L010646
BDB010646
|
BDBM224218
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3CF)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C26H29ClFN7O3 542.015000 |
IMWRYGCJUWRPLK-GPMSIDNRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224218
|
Local ready
Direct docking supported
|
|
E3L010647
BDB010647
|
BDBM224219
Cc1nnc([C@@H]2COCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)o1
|
C28H30ClN9O4 592.060000 |
PRHWXDMZKMBNHQ-KNBMTAEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224219
|
Local ready
Direct docking supported
|
|
E3L010648
BDB010648
|
BDBM224220
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3CF)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H28ClFN8O3 543.003000 |
JBFYWIZNRHVHCW-IIDMSEBBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224220
|
Local ready
Direct docking supported
|
|
E3L010649
BDB010649
|
BDBM224221
C[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H31ClN8O3 539.040000 |
VOXJMEPEQFUQDQ-QBPKDAKJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224221
|
Local ready
Direct docking supported
|
|
E3L010650
BDB010650
|
BDBM224222
Cc1nnc(C2CCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)o1
|
C27H29ClN10O3 577.049000 |
GNBNCCUHOCLHMY-JGKZKGBNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224222
|
Local ready
Direct docking supported
|
|
E3L010651
BDB010651
|
BDBM224223
C[C@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H34ClN7O3 600.123000 |
UXFYSVQWWYMTNL-AXMKBWGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224223
|
Local ready
Direct docking supported
|
|
E3L010652
BDB010652
|
BDBM224224
Cc1noc(C2CCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C27H29ClN10O3 577.049000 |
OFZADLYVGDZSQM-JGKZKGBNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224224
|
Local ready
Direct docking supported
|
|
E3L010653
BDB010653
|
BDBM224225
C[C@H]1CC[C@H](Cn2c(N3CCOCC34CCC4)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C27H31ClN8O3 551.051000 |
NYCYQCVQSJEWFC-QAQDUYKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224225
|
Local ready
Direct docking supported
|
|
E3L010654
BDB010654
|
BDBM224226
Cc1noc(C2CCCN2c2nc3nc(C(=O)O)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C26H29ClN8O3 537.024000 |
QDKPVDBVVFZWSM-JGKZKGBNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224226
|
Local ready
Direct docking supported
|
|
E3L010655
BDB010655
|
BDBM224227
Cc1noc(C2CCCN2c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C27H29ClN10O3 577.049000 |
NRUAEEHPNZLUFU-JGKZKGBNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224227
|
Local ready
Direct docking supported
|
|
E3L010656
BDB010656
|
BDBM224228
C[C@@H]1COC[C@@H](C)N1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H32ClN7O3 538.052000 |
MXBOXVQVGCQEQY-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224228
|
Local ready
Direct docking supported
|
|
E3L010657
BDB010657
|
BDBM224229
CN(C)C(=O)[C@@H]1CCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H33ClN8O3 565.078000 |
JQAOAOJPJBBSOF-ZWOKBUDYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224229
|
Local ready
Direct docking supported
|
|
E3L010658
BDB010658
|
BDBM224230
COC[C@@H]1CC[C@@H](COC)N1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H36ClN7O4 582.105000 |
GRMQEAOYJQZKOI-GPHNJDIKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224230
|
Local ready
Direct docking supported
|
|
E3L010659
BDB010659
|
BDBM224231
C[C@H]1CC[C@H](Cn2c(N3CCC4OCCC43)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C27H30ClN7O3 536.036000 |
DOGLHDRNXYDXCI-OCUOFVAZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224231
|
Local ready
Direct docking supported
|
|
E3L010660
BDB010660
|
BDBM224232
CC1CO[C@@H]2CCC[C@H]2N1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H33ClN8O3 565.078000 |
ORXYRXMKBNCXOQ-SRJMTFKNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224232
|
Local ready
Direct docking supported
|