| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010621
BDB010621
|
BDBM224191
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4ccnc(Cl)c4)c32)CC1
|
C30H31ClN8O3 587.084000 |
DJIPHZDJKNRNHV-IPJJNNNSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224191
|
Local ready
Direct docking supported
|
|
E3L010622
BDB010622
|
BDBM224192
CS(=O)(=O)c1cc(Cl)cc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C32H34ClN7O5S 664.188000 |
BBXIGBSBPWRLKO-RLSLOFABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224192
|
Local ready
Direct docking supported
|
|
E3L010623
BDB010623
|
BDBM224193
Cc1nc(-c2cccc(-c3nc(-c4noc(=O)[nH]4)nc4nc(N5CCOC[C@H]5c5ccccc5)n(C[C@H]5CC[C@H](C)CC5)c34)c2)no1
|
C34H35N9O4 633.713000 |
UWSNFGZGXLHVQU-YBXDKENTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224193
|
Local ready
Direct docking supported
|
|
E3L010624
BDB010624
|
BDBM224194
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cc(N5CCCC5)c4)c32)CC1
|
C35H39ClN8O3 655.203000 |
MCZAJNXCNHGWEK-LXWOLXCRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224194
|
Local ready
Direct docking supported
|
|
E3L010625
BDB010625
|
BDBM224195
Cc1cc(Cl)cc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C32H34ClN7O3 600.123000 |
CURMPYQUYMWHPG-OWHZGTRUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224195
|
Local ready
Direct docking supported
|
|
E3L010626
BDB010626
|
BDBM224196
Cc1cncc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C31H34N8O3 566.666000 |
ZGVGUMSYAIMDNW-PTLVVNQVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224196
|
Local ready
Direct docking supported
|
|
E3L010627
BDB010627
|
BDBM224197
Cc1noc([C@@H]2COCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C28H30ClN9O4 592.060000 |
KVJZMGOQIOKFFG-KNBMTAEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224197
|
Local ready
Direct docking supported
|
|
E3L010628
BDB010628
|
BDBM224198
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3C(N)=O)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C26H29ClN8O4 553.023000 |
DEOBEKQDDSVVNI-MPGHIAIKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224198
|
Local ready
Direct docking supported
|
|
E3L010629
BDB010629
|
BDBM224199
C[C@H]1CC[C@H](Cn2c(N3CCCC4OCCCC43)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
LDGINTLRMUZBRI-CJRKGXOXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224199
|
Local ready
Direct docking supported
|
|
E3L010630
BDB010630
|
BDBM224200
C[C@H]1CC[C@H](Cn2c(N3CCCC4COCCC43)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
ADSHWWMZKYFURJ-AMJWBLJWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224200
|
Local ready
Direct docking supported
|
|
E3L010631
BDB010631
|
BDBM224201
Cc1csc([C@@H]2COCCN2c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C29H31ClN8O3S 607.140000 |
UIMOFRIROMCXHL-MDKPJZGXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224201
|
Local ready
Direct docking supported
|
|
E3L010632
BDB010632
|
BDBM224202
Cc1noc([C@@H]2COCCN2c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)n1
|
C28H30ClN9O4 592.060000 |
YFXPERDAKINMPM-KNBMTAEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224202
|
Local ready
Direct docking supported
|
|
E3L010633
BDB010633
|
BDBM224203
C[C@H]1CC[C@H](Cn2c(N3CCCC4COCCC43)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H33ClN8O3 565.078000 |
XSUFWLVWLWNXBX-KQUKSJNGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224203
|
Local ready
Direct docking supported
|
|
E3L010634
BDB010634
|
BDBM224205
C[C@H]1CC[C@H](Cn2c(N3CCCC4COCCC43)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C29H34ClN7O3 564.090000 |
QKMDPCIHIPAEBY-AMJWBLJWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224205
|
Local ready
Direct docking supported
|
|
E3L010635
BDB010635
|
BDBM224207
C[C@@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H34ClN7O3 600.123000 |
XMZFQPXCAJIGHD-JYEBCORGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224207
|
Local ready
Direct docking supported
|
|
E3L010636
BDB010636
|
BDBM224208
C[C@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C32H34ClN7O3 600.123000 |
XMZFQPXCAJIGHD-AXMKBWGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224208
|
Local ready
Direct docking supported
|
|
E3L010637
BDB010637
|
BDBM224209
C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCCC43)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H33ClN8O3 565.078000 |
UJZPIFLQBYAWAQ-QHGDOQTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224209
|
Local ready
Direct docking supported
|
|
E3L010638
BDB010638
|
BDBM224210
C[C@@H]1OCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C31H33ClN8O3 601.111000 |
BQYKCUJMTWHUEF-GBWYYYKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224210
|
Local ready
Direct docking supported
|
|
E3L010639
BDB010639
|
BDBM224211
C[C@@H]1OCCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)[C@@H]1c1ccccc1
|
C31H33ClN8O3 601.111000 |
MNFALKSWLMSBID-GBWYYYKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224211
|
Local ready
Direct docking supported
|
|
E3L010640
BDB010640
|
BDBM224212
C[C@H]1CC[C@H](Cn2c(N3CCOC4CCCCC43)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C28H33ClN8O3 565.078000 |
PPNAAEISNSMFCY-QHGDOQTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224212
|
Local ready
Direct docking supported
|