| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010661
BDB010661
|
BDBM224233
CC[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H33ClN8O3 553.067000 |
ASICCLMDYGYXKJ-WOCWXWTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224233
|
Local ready
Direct docking supported
|
|
E3L010662
BDB010662
|
BDBM224234
CC[C@@H]1[C@@H](C)OCCN1c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H33ClN8O3 553.067000 |
SJEZDMAQYSMRBB-WOCWXWTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224234
|
Local ready
Direct docking supported
|
|
E3L010663
BDB010663
|
BDBM224235
COC1CCN(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)C(C)C1
|
C27H33ClN8O3 553.067000 |
JRMSAGQVAUUCJU-QYSSCYCTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224235
|
Local ready
Direct docking supported
|
|
E3L010664
BDB010664
|
BDBM224237
COc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H33ClN8O4 617.110000 |
TXPOUVLMYXESNB-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224237
|
Local ready
Direct docking supported
|
|
E3L010665
BDB010665
|
BDBM224238
COc1ncc(Cl)cc1-c1nc(-c2n[nH]c(=O)o2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H33ClN8O4 617.110000 |
OBGHFEJURFIFGJ-YDHSSHFGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224238
|
Local ready
Direct docking supported
|
|
E3L010666
BDB010666
|
BDBM224239
Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H33ClN8O3 601.111000 |
WWZHOOCMOKOEQT-WXVUKLJWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224239
|
Local ready
Direct docking supported
|
|
E3L010667
BDB010667
|
BDBM224240
Cc1ncc(Cl)cc1-c1nc(-c2n[nH]c(=O)o2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12
|
C31H33ClN8O3 601.111000 |
DNPWNFGBISXBLL-WXVUKLJWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224240
|
Local ready
Direct docking supported
|
|
E3L010668
BDB010668
|
BDBM224241
COCCOc1cc(Cl)cc(-c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC5CCCC54)n(C[C@H]4CC[C@H](C)CC4)c23)c1
|
C31H38ClN7O5 624.142000 |
FKFCTGIGSXYQKX-UUNOQGSESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224241
|
Local ready
Direct docking supported
|
|
E3L010669
BDB010669
|
BDBM224242
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cnc4OCc4ccccc4)c32)CC1
|
C37H37ClN8O4 693.208000 |
MDBGNLQFZFAZAQ-MOMDTQCHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224242
|
Local ready
Direct docking supported
|
|
E3L010670
BDB010670
|
BDBM224243
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cc(Cl)cnc4O)c32)CC1
|
C30H31ClN8O4 603.083000 |
MTXPXGKDRWNYJT-SPEDKVCISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224243
|
Local ready
Direct docking supported
|
|
E3L010671
BDB010671
|
BDBM224244
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cc(Cl)cnc4O)c32)CC1
|
C30H31ClN8O4 603.083000 |
IEHDQFSONZSPMS-SPEDKVCISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224244
|
Local ready
Direct docking supported
|
|
E3L010672
BDB010672
|
BDBM224245
Cc1ncc(Cl)cc1-c1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC4CCCC43)n(C[C@H]3CC[C@H](C)CC3)c12
|
C28H33ClN8O3 565.078000 |
YXAWTPXTJVBMAL-SAFFZPNTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224245
|
Local ready
Direct docking supported
|
|
E3L010673
BDB010673
|
BDBM224246
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(C4CCCCC4)c32)CC1
|
C31H39N7O3 557.699000 |
JMCPMEGRCZVXIF-HFMPRLQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224246
|
Local ready
Direct docking supported
|
|
E3L010674
BDB010674
|
BDBM224247
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4n[nH]c(=O)o4)nc(C4CCCCC4)c32)CC1
|
C31H39N7O3 557.699000 |
RJNGGTRYRMJHCX-HFMPRLQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224247
|
Local ready
Direct docking supported
|
|
E3L010675
BDB010675
|
BDBM224248
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(C4CCOCC4)c32)CC1
|
C30H37N7O4 559.671000 |
MTLKVCYWWSMBQE-JTAQYXEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224248
|
Local ready
Direct docking supported
|
|
E3L010676
BDB010676
|
BDBM224249
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4n[nH]c(=O)o4)nc(C4CCOCC4)c32)CC1
|
C30H37N7O4 559.671000 |
YJRQJWMEXPIUBK-JTAQYXEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224249
|
Local ready
Direct docking supported
|
|
E3L010677
BDB010677
|
BDBM224250
CC1CCCC(c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)C1
|
C32H41N7O3 571.726000 |
YXBJPWBCJWFLST-AZQWGEHQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224250
|
Local ready
Direct docking supported
|
|
E3L010678
BDB010678
|
BDBM224251
CC1CCCC(c2nc(-c3n[nH]c(=O)o3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)C1
|
C32H41N7O3 571.726000 |
YDMWXFMYYWUTND-AZQWGEHQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224251
|
Local ready
Direct docking supported
|
|
E3L010679
BDB010679
|
BDBM224252
CCOc1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C23H19F3N4O3 456.424000 |
KXHDVBZZTRBVLI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM224252; PubChem:CID90318228
|
Local ready
Direct docking supported
|
|
E3L010680
BDB010680
|
BDBM224253
Cc1cccc(-c2nc3nc(C(=O)O)nc(OCC4CC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C25H21F3N4O3 482.462000 |
KZJCHEUOCAVTIF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM224253; PubChem:CID90317665
|
Local ready
Direct docking supported
|