| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010681
BDB010681
|
BDBM224254
Cc1cccc(-c2nc3nc(C(=O)O)nc(OCC4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C26H23F3N4O3 496.489000 |
KWPWXXWXCTUXRU-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM224254; PubChem:CID90317868
|
Local ready
Direct docking supported
|
|
E3L010682
BDB010682
|
BDBM224255
Cc1cccc(-c2nc3nc(C(=O)O)nc(OC(C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H25F3N4O3 510.516000 |
NJQNBWQRXZSFKH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM224255; PubChem:CID90318715
|
Local ready
Direct docking supported
|
|
E3L010683
BDB010683
|
BDBM224258
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(OC(C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)c(F)c2)c1
|
C28H27F4N5O3 557.548000 |
OCFLERPJFLWYJY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM224258; PubChem:CID90318515
|
Local ready
Direct docking supported
|
|
E3L010684
BDB010684
|
BDBM224259
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(OC(C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c1
|
C28H37N5O3 491.636000 |
RTRXLBZTEBOHLE-DDAAKYIKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224259
|
Local ready
Direct docking supported
|
|
E3L010685
BDB010685
|
BDBM224260
CC(=O)N1CCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C28H41N9O3 551.696000 |
ZTTMFDQAVKWEPY-SOAMZJECSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224260
|
Local ready
Direct docking supported
|
|
E3L010686
BDB010686
|
BDBM224261
CC(=O)N1CCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](c2ccccc2)C1
|
C33H43N9O3 613.767000 |
QLSXOXRHMJYZIW-YNMPZUNCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224261
|
Local ready
Direct docking supported
|
|
E3L010687
BDB010687
|
BDBM224262
CC(=O)N1CCN(c2nc3nc(C(N)=O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](c2ccccc2)C1
|
C32H44N8O2 572.758000 |
ZIYLRHHUZRSPOW-YNMPZUNCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224262
|
Local ready
Direct docking supported
|
|
E3L010688
BDB010688
|
BDBM224263
C[C@@H](Nc1nc(C(N)=O)nc2nc(N3CCN(S(C)(=O)=O)C[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H44N8O3S 608.813000 |
MFIXSUBBSCVXOZ-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224263
|
Local ready
Direct docking supported
|
|
E3L010689
BDB010689
|
BDBM224264
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCN(S(C)(=O)=O)C[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H43N9O4S 649.822000 |
JPXMCAWABSTAQN-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224264
|
Local ready
Direct docking supported
|
|
E3L010690
BDB010690
|
BDBM224265
C[C@@H]1CN(S(C)(=O)=O)CCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H41N9O4S 587.751000 |
BBRAUEGPLGKYFS-NCXUSEDFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224265
|
Local ready
Direct docking supported
|
|
E3L010691
BDB010691
|
BDBM224266
C[C@@H]1CN(C(=O)C(C)(C)C)CCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H47N9O3 593.777000 |
QRENBZGJZPXUJX-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224266
|
Local ready
Direct docking supported
|
|
E3L010692
BDB010692
|
BDBM224267
C[C@@H]1CN(C(=O)C2CC2)CCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H43N9O3 577.734000 |
KWEBARMWWVLUGT-UAFMIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224267
|
Local ready
Direct docking supported
|
|
E3L010693
BDB010693
|
BDBM224268
CC(C)S(=O)(=O)N1CCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)[C@H](C)C1
|
C29H45N9O4S 615.805000 |
KHJXRSXKSRWQAV-XRXFAXGQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224268
|
Local ready
Direct docking supported
|
|
E3L010694
BDB010694
|
BDBM224269
C[C@@H]1CN(C(=O)CO)CCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H41N9O4 567.695000 |
ARSVJCLIYDJWHX-NCXUSEDFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224269
|
Local ready
Direct docking supported
|
|
E3L010695
BDB010695
|
BDBM224270
C[C@@H]1CNCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H39N9O2 509.659000 |
ZRYGBGHDKYFLST-BRSBDYLESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224270
|
Local ready
Direct docking supported
|
|
E3L010696
BDB010696
|
BDBM224271
C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C32H49N9O4 623.803000 |
XFJPDQUVPCVCDT-QMCAAQAGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224271
|
Local ready
Direct docking supported
|
|
E3L010697
BDB010697
|
BDBM224272
C[C@@H]1CN[C@@H](C)CN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H41N9O2 523.686000 |
RXTMEPQQOPRGDH-QTMHVTGLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224272
|
Local ready
Direct docking supported
|
|
E3L010698
BDB010698
|
BDBM224273
CC(=O)N1C[C@@H](C)N(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C[C@@H]1C
|
C29H43N9O3 565.723000 |
AJZYGNXFBYSIEH-RFBJODPTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224273
|
Local ready
Direct docking supported
|
|
E3L010699
BDB010699
|
BDBM224274
C[C@@H]1CN(C(=O)C2CC2)[C@@H](C)CN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C31H45N9O3 591.761000 |
LZNKBZCBLAOCOW-AFDCHOCNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224274
|
Local ready
Direct docking supported
|
|
E3L010700
BDB010700
|
BDBM224275
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C(F)(F)F)CC2)c1
|
C28H35F3N6O2 544.622000 |
IFMPCNITMJPZJI-MBOZVWFJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224275
|
Local ready
Direct docking supported
|