| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010941
BDB010941
|
BDBM227006
C[C@H]1CCCN(Cc2cc(C(=O)Nc3cccc([C@]4(c5nncn5C)C[C@H](C)C4)c3)c(F)c(C(F)(F)F)c2)C1
|
C29H33F4N5O 543.609000 |
RBMVUVGBYXVXMY-CLWPXKJUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227006
|
Local ready
Direct docking supported
|
|
E3L010942
BDB010942
|
US20260008770, Example 30
CC1CC(c2cccc(NC(=O)c3cc(CN4CCC[C@H](C)C4)cc(C(F)(F)F)c3)c2)(c2nncn2C)C1
|
C29H34F3N5O 525.619000 |
QKHWQKJNZYFRBJ-MPBYYLQUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227007; PubChem:CID178290367
|
Local ready
Direct docking supported
|
|
E3L010943
BDB010943
|
US20260008770, Example 31
C[C@H]1CCCN(Cc2cc(C(=O)Nc3cccc(C(c4nncn4C)C4CCC4)c3)cc(C(F)(F)F)c2)C1
|
C29H34F3N5O 525.619000 |
RFVXGZZUUBBCNF-SXMXNQBWSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227008; PubChem:CID178290368
|
Local ready
Direct docking supported
|
|
E3L010944
BDB010944
|
US20260008770, Example 32
C#CC1CC(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4n3)c2)(c2nncn2C)C1
|
C30H31F3N6 532.614000 |
GEHMCZWGMBWWIN-JPZAJBPPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227009; PubChem:CID178290369
|
Local ready
Direct docking supported
|
|
E3L010945
BDB010945
|
US20260008770, Example 33
COCC1CC(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4n3)c2)(c2nncn2C)C1
|
C30H35F3N6O 552.645000 |
AIQYVTGZQCZWOF-OQTSKEGVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227010; PubChem:CID178290370
|
Local ready
Direct docking supported
|
|
E3L010946
BDB010946
|
BDBM227011
CC1CN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)ccn4)c(=O)c3c2)CCC1(F)F
|
C29H30F5N7O 587.597000 |
HMOFPBHNVIAIFZ-FBTNBPGASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227011
|
Local ready
Direct docking supported
|
|
E3L010947
BDB010947
|
US20260008770, Example 35
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc(C5(Cc6nncn6C)COC5)ccn4)c(=O)c3c2)C1
|
C28H30F3N7O2 553.589000 |
HGRZFEGRHGLAPV-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227012; PubChem:CID178290372
|
Local ready
Direct docking supported
|
|
E3L010948
BDB010948
|
BDBM227013
Cn1cnnc1[C@]1(c2ccnc(-n3ncc4c(C(F)(F)F)cc(CN5CCC6(CC6)C5)cc4c3=O)c2)C[C@H](C)C1
|
C29H30F3N7O 549.601000 |
UDSXUORSIZXKEG-CHOKWEPUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227013
|
Local ready
Direct docking supported
|
|
E3L010949
BDB010949
|
BDBM227014
Cn1cnnc1[C@]1(c2ccnc(-n3ncc4c(C(F)(F)F)cc(CN5CCCC6(CC6)C5)cc4c3=O)c2)C[C@H](C)C1
|
C30H32F3N7O 563.628000 |
QMHFVMKXASDSPX-CGSFZAOMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227014
|
Local ready
Direct docking supported
|
|
E3L010950
BDB010950
|
US20260008770, Example 38
CC1CC(c2cc(OCF)nc(-n3ncc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C30H33F4N7O2 599.633000 |
WEBHTOAHPGRKNP-PYJILBCDSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227015; PubChem:CID178290375
|
Local ready
Direct docking supported
|
|
E3L010951
BDB010951
|
BDBM227016
Cn1cnnc1[C@]1(c2ccnc(-n3ncc4c(C(F)(F)F)cc(CN5CCOC6(CCC6)C5)cc4c3=O)c2)C[C@H](C)C1
|
C30H32F3N7O2 579.627000 |
QNBDNUOQUULWKD-CGSFZAOMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227016
|
Local ready
Direct docking supported
|
|
E3L010952
BDB010952
|
BDBM227017
Cn1cnnc1[C@]1(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCOC6(CCC6)C5)cc4n3)c2)C[C@H](C)C1
|
C30H33F3N6O 550.629000 |
CODMIGGXJFOVFW-VTNQZFKNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227017
|
Local ready
Direct docking supported
|
|
E3L010953
BDB010953
|
US20260008770, Example 41
CC1CC(c2cc(Cl)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C29H31ClF3N7O 586.062000 |
VCXFVORHQWPBAF-FESOMXASSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227018; PubChem:CID178290378
|
Local ready
Direct docking supported
|
|
E3L010954
BDB010954
|
BDBM227019
C#CC[C@H]1CCCN(Cc2cc(C(F)(F)F)c3cn(-c4cccc([C@]5(c6nncn6C)C[C@@H](C)C5)c4)nc3c2)C1
|
C31H33F3N6 546.641000 |
LDTXFHLJYAGSLM-MWXNICTNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227019
|
Local ready
Direct docking supported
|
|
E3L010955
BDB010955
|
US20260008770, Example 43
CNC(=O)c1cc(-n2cc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3n2)cc(C2(c3nncn3C)CC(C)C2)c1
|
C31H36F3N7O 579.671000 |
NUNUOPMDOOPKNJ-BVSSOPRRSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227020; PubChem:CID178290380
|
Local ready
Direct docking supported
|
|
E3L010956
BDB010956
|
US20260008770, Example 44
CC1CC(c2cc(F)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C29H31F4N7O 569.607000 |
QAHIKGDDXGUGSS-FESOMXASSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227021; PubChem:CID178290381
|
Local ready
Direct docking supported
|
|
E3L010957
BDB010957
|
US20260008770, Example 45
Cc1cc(C2(c3nncn3C)CC(C)C2)cc(-n2cnc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C30H34F3N7O 565.644000 |
GYYNHGDVZHFRMD-PYJILBCDSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227022; PubChem:CID178290382
|
Local ready
Direct docking supported
|
|
E3L010958
BDB010958
|
US20260008770, Example 46
CC1CC(c2ccnc(-n3cnc4c(C(F)(F)F)c(CN5CCC[C@H](C)C5)[nH]c4c3=O)c2)(c2nncn2C)C1
|
C27H31F3N8O 540.594000 |
FQSPLVOJCGCOMH-VZMMAYBGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227023; PubChem:CID178290383
|
Local ready
Direct docking supported
|
|
E3L010959
BDB010959
|
US20260008770, Example 47
CC1CC(c2cc(C3CC3)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C32H36F3N7O 591.682000 |
OKMLPLUQLOGPEN-YQTVFLROSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227024; PubChem:CID178290384
|
Local ready
Direct docking supported
|
|
E3L010960
BDB010960
|
BDBM227025
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C(F)F)C[C@@H](C)C5)ccn4)c(=O)c3c2)C1
|
C29H30F5N7O 587.597000 |
ZJBMVKPHFUGRKY-PCXSUYPWSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227025
|
Local ready
Direct docking supported
|