| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L011001
BDB011001
|
US20260008770, Example 89
CC1CC(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@@](C)(O)C5)cc4n3)c2)(c2nncn2C)C1
|
C29H33F3N6O 538.618000 |
NKIZHTOKYRMNBS-NIPITBOXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227066; PubChem:CID178290419
|
Local ready
Direct docking supported
|
|
E3L011002
BDB011002
|
US20260008770, Example 90
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3cn(-c4cccc(C5(c6nncn6C)CC(CC#N)C5)c4)nc3c2)C1
|
C30H32F3N7 547.629000 |
OJWFUEMNLRAWKC-JPZAJBPPSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227067; PubChem:CID178290420
|
Local ready
Direct docking supported
|
|
E3L011003
BDB011003
|
US20260008770, Example 91
CC1CC(c2cncc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4n3)c2)(c2nncn2C)C1
|
C28H32F3N7 523.607000 |
SBLPTNPDKJVLOA-SIYOEGHHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227068; PubChem:CID178290421
|
Local ready
Direct docking supported
|
|
E3L011004
BDB011004
|
BDBM227069
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3cn(-c4cccc([C@]5(c6nncn6C)C[C@@H](OC(F)(F)F)C5)c4)nc3c2)C1
|
C29H30F6N6O 592.588000 |
AFTWUEPYKOAGOB-SFBLDSMTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227069
|
Local ready
Direct docking supported
|
|
E3L011005
BDB011005
|
BDBM227070
CCc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(-n2cnc3ccc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C30H37N7O 511.674000 |
VCHNFJCNSQPPBX-FNFPNEPISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227070
|
Local ready
Direct docking supported
|
|
E3L011006
BDB011006
|
BDBM227071
C=Cc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(-n2cnc3ccc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C30H35N7O 509.658000 |
BVGANKHDXKPMLG-FNFPNEPISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227071
|
Local ready
Direct docking supported
|
|
E3L011007
BDB011007
|
BDBM227072
CC(c1ccc2ncn(-c3cc([C@]4(c5nncn5C)C[C@@H](C)C4)cc(OCF)n3)c(=O)c2c1)N1CCC[C@H](C)C1
|
C30H36FN7O2 545.663000 |
VGVYEPAJYVOBHJ-IQUXKSBZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227072
|
Local ready
Direct docking supported
|
|
E3L011008
BDB011008
|
BDBM227073
C[C@H]1CCCN(Cc2ccc3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(C5CC5)n4)c(=O)c3c2)C1
|
C31H37N7O 523.685000 |
WPUCWKSWWYSKHJ-VAKBQEFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227073
|
Local ready
Direct docking supported
|
|
E3L011009
BDB011009
|
BDBM227074
C#Cc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(-n2cnc3ccc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C30H33N7O 507.642000 |
IADBDSBTNFKAIP-FNFPNEPISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227074
|
Local ready
Direct docking supported
|
|
E3L011010
BDB011010
|
BDBM227075
Cn1cnnc1[C@]1(c2cc(OCF)nc(-n3cnc4ccc(CN5CCC[C@H](F)C5)cc4c3=O)c2)C[C@H](C)C1
|
C28H31F2N7O2 535.599000 |
RDQIDAPLOSUJOS-GZDZOCAYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227075
|
Local ready
Direct docking supported
|
|
E3L011011
BDB011011
|
BDBM227076
Cn1cnnc1[C@]1(c2cc(OCF)nc(-n3cnc4cnc(CN5CCC[C@H](F)C5)cc4c3=O)c2)C[C@H](C)C1
|
C27H30F2N8O2 536.587000 |
NRAVBNBBXIOLFQ-GYERCMHNSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227076
|
Local ready
Direct docking supported
|
|
E3L011012
BDB011012
|
BDBM227077
C[C@H]1CCCN(Cc2cc3c(=O)n(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)cnc3cc2F)C1
|
C29H33F2N7O2 549.626000 |
MFZFONNELXWQDP-XFLNKKNVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227077
|
Local ready
Direct docking supported
|
|
E3L011013
BDB011013
|
US20260008770, Example 101
C#CC1CC(c2ccnc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C30H30F3N7O 561.612000 |
MISVUXRIQGLQOX-QORSJFMISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227078; PubChem:CID178290431
|
Local ready
Direct docking supported
|
|
E3L011014
BDB011014
|
BDBM227079
Cn1cnnc1[C@]1(c2cc(OCF)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](F)C5)cc4c3=O)c2)C[C@H](C)C1
|
C29H30F5N7O2 603.596000 |
BDPCOIQQRWOJBG-CJBMVKJXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227079
|
Local ready
Direct docking supported
|
|
E3L011015
BDB011015
|
US20260008770, Example 103
CC1CC(c2cc(OC(F)F)nc(-n3cnc4c(C(F)(F)F)cc(C(C)N5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C31H34F5N7O2 631.650000 |
WPCZXQWRMQVFRR-MYCZZPCFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227080; PubChem:CID178290433
|
Local ready
Direct docking supported
|
|
E3L011016
BDB011016
|
BDBM227081
[2H]C([2H])(c1cc(C(F)(F)F)c2ncn(-c3cccc([C@]4(c5nncn5C)C[C@@H](C)C4)c3)c(=O)c2c1)N1CCC[C@H](C)C1
|
C30H33F3N6O 552.641204 |
OPLYLGJCVDRCFK-HXUFRDODSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227081
|
Local ready
Direct docking supported
|
|
E3L011017
BDB011017
|
BDBM227082
Cn1cnnc1[C@]1(c2ccnc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](CF)C5)cc4c3=O)c2)C[C@H](C)C1
|
C29H31F4N7O 569.607000 |
HYUBHTRYCIWTFY-BCRFLOQVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227082
|
Local ready
Direct docking supported
|
|
E3L011018
BDB011018
|
BDBM227083
C[C@@H]1CN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)CCC1F
|
C30H32F5N7O2 617.623000 |
NZVFWPJEHPPSAD-WOVMZZQXSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227083
|
Local ready
Direct docking supported
|
|
E3L011019
BDB011019
|
BDBM227084
C=C(F)c1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(-n2cnc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C31H33F4N7O 595.645000 |
ODISKKCTZKFERN-XYSIDCHVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227084
|
Local ready
Direct docking supported
|
|
E3L011020
BDB011020
|
BDBM227085
Cn1cnnc1[C@]1(c2cc(OCF)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCCC(C)(F)C5)cc4c3=O)c2)C[C@H](C)C1
|
C30H32F5N7O2 617.623000 |
OUHVFDXKEQLMAH-IOPLCCCZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227085
|
Local ready
Direct docking supported
|