| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L011041
BDB011041
|
BDBM227468
C[C@H]1CC[C@H](Cn2c(C3(F)CCCCC3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C26H29ClFN7O2 526.016000 |
BEVAKONXWKJOFL-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227468
|
Local ready
Direct docking supported
|
|
E3L011042
BDB011042
|
BDBM227469
COC(C)(c1ncoc1C)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H30ClN7O4 564.046000 |
IDQWGBZTRFPRJP-MVLNGOCHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227469
|
Local ready
Direct docking supported
|
|
E3L011043
BDB011043
|
BDBM227470
CC(F)(c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C27H31ClFN7O2 540.043000 |
XZEMECYIGBOGNS-FTKIHKAUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227470
|
Local ready
Direct docking supported
|
|
E3L011044
BDB011044
|
BDBM227473
CC(F)(c1cccc(Cl)c1F)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H25Cl2F2N7O2 600.457000 |
BVBWWRVJJDOVTC-ADKDQLFJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227473
|
Local ready
Direct docking supported
|
|
E3L011045
BDB011045
|
BDBM227476
COC(c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C27H32ClN7O3 538.052000 |
CBCJHYSDWMWJIZ-STFKQGPRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227476
|
Local ready
Direct docking supported
|
|
E3L011046
BDB011046
|
BDBM227477
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCC1
|
C25H28ClN7O3 509.998000 |
VBOMPVICMRQHGR-SHTZXODSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227477
|
Local ready
Direct docking supported
|
|
E3L011047
BDB011047
|
BDBM227648
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCCCC1C
|
C28H34ClN7O3 552.079000 |
FQJJKIJLMZTVBI-YEWODGJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227648
|
Local ready
Direct docking supported
|
|
E3L011048
BDB011048
|
BDBM227649
COC1(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCCCC1C
|
C28H34ClN7O3 552.079000 |
RNUBRCBXMMRKJR-YEWODGJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227649
|
Local ready
Direct docking supported
|
|
E3L011049
BDB011049
|
BDBM227650
CC1CCCCC1(F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H31ClFN7O2 540.043000 |
MKSBRJNMCJESSA-MSDPPIFYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227650
|
Local ready
Direct docking supported
|
|
E3L011050
BDB011050
|
BDBM227651
CC(F)(c1ccccc1F)c1nc2nc(C(=O)O)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H26ClF2N5O2 525.987000 |
VKSZBMNCNZFIIR-FTKIHKAUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227651
|
Local ready
Direct docking supported
|
|
E3L011051
BDB011051
|
BDBM227653
CC(F)(c1c(F)cccc1F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H25ClF3N7O2 584.002000 |
KZZHHIKJYHHMJY-ADKDQLFJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227653
|
Local ready
Direct docking supported
|
|
E3L011052
BDB011052
|
BDBM227655
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)COC1
|
C24H26ClN7O4 511.970000 |
ZSVDDURNHVMGDJ-HDJSIYSDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227655
|
Local ready
Direct docking supported
|
|
E3L011053
BDB011053
|
BDBM227656
COC(C)(c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C28H34ClN7O3 552.079000 |
MHZJACQPAYODHS-KEQYIYAOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227656
|
Local ready
Direct docking supported
|
|
E3L011054
BDB011054
|
BDBM227657
COC(C)(c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCCC1
|
C28H34ClN7O3 552.079000 |
QBPASAFYIDRBEC-KEQYIYAOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227657
|
Local ready
Direct docking supported
|
|
E3L011055
BDB011055
|
BDBM227658
COC(C)(c1cccc(Cl)c1F)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H28Cl2FN7O3 612.493000 |
BUMUMRGRUDJIND-RFQKMOMISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227658
|
Local ready
Direct docking supported
|
|
E3L011056
BDB011056
|
BDBM227660
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCCCC1
|
C27H32ClN7O3 538.052000 |
JDAWCGLLGGCZGR-QAQDUYKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227660
|
Local ready
Direct docking supported
|
|
E3L011057
BDB011057
|
BDBM227661
COC1(c2nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCCCC1
|
C27H32ClN7O3 538.052000 |
VOHLSYOFEBWXDH-QAQDUYKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227661
|
Local ready
Direct docking supported
|
|
E3L011058
BDB011058
|
BDBM227662
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2C[C@H]2CC[C@H](C)CC2)CCCC1
|
C26H30ClN7O3 524.025000 |
ORQPCIFJOFOXHA-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227662
|
Local ready
Direct docking supported
|
|
E3L011059
BDB011059
|
BDBM227663
COc1ccccc1C(C)(OC)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H32ClN7O4 590.084000 |
YJQRGFLZUAUQDK-VVOUQJEZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227663
|
Local ready
Direct docking supported
|
|
E3L011060
BDB011060
|
BDBM227664
COc1ccccc1C(C)(OC)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H32ClN7O4 590.084000 |
NFOWTYQEEXRHCE-VVOUQJEZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227664
|
Local ready
Direct docking supported
|