| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L011021
BDB011021
|
BDBM227086
CC1CN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)CCC1(F)F
|
C30H31F6N7O2 635.613000 |
VPFPKAQFLJFPQZ-PMDKZGMCSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227086
|
Local ready
Direct docking supported
|
|
E3L011022
BDB011022
|
BDBM227087
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C6CCC6)C[C@@H](C)C5)ccn4)c(=O)c3c2)C1
|
C32H36F3N7O 591.682000 |
IPEOEWWNUWLCTK-VAKBQEFHSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227087
|
Local ready
Direct docking supported
|
|
E3L011023
BDB011023
|
BDBM227088
C[C@H]1CCCN(Cc2cc(F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)C1
|
C29H33F2N7O2 549.626000 |
YGIDUNKJVPDSBO-XFLNKKNVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227088
|
Local ready
Direct docking supported
|
|
E3L011024
BDB011024
|
BDBM227089
C[C@H]1CCCN(Cc2ccc3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)C1
|
C29H34FN7O2 531.636000 |
QQIBXYUZHBDSIG-QWQFASRJSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227089
|
Local ready
Direct docking supported
|
|
E3L011025
BDB011025
|
US20260008770, Example 113
[2H]c1nnc(C2(c3ccnc(-n4cnc5c(C(F)(F)F)cc(CN6CCC[C@H](C)C6)cc5c4=O)c3)CC(C)C2)n1C(F)F
|
C29H30F5N7O 588.603102 |
ZJBMVKPHFUGRKY-KGNWANMCSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227090; PubChem:CID178290443
|
Local ready
Direct docking supported
|
|
E3L011026
BDB011026
|
BDBM227091
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](CF)C5)ccn4)c(=O)c3c2)C1
|
C29H31F4N7O 569.607000 |
JANCVYSYUKJUIG-JRZYIBAFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227091
|
Local ready
Direct docking supported
|
|
E3L011027
BDB011027
|
BDBM227092
COc1cc([C@]2(c3nncn3C)C[C@@H](C)C2)cc(-n2cnc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3c2=O)n1
|
C30H34F3N7O2 581.643000 |
HXNIRMZHZFNJJK-XFLNKKNVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227092
|
Local ready
Direct docking supported
|
|
E3L011028
BDB011028
|
US20260008770, Example 116
C=Cn1cnnc1C1(c2ccnc(-n3ncc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)CC(C)C1
|
C30H32F3N7O 563.628000 |
VTXWWMFRMBFHMI-QORSJFMISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227093; PubChem:CID178290446
|
Local ready
Direct docking supported
|
|
E3L011029
BDB011029
|
US20260008770, Example 117
CC1CC(c2cc(OC(F)F)nc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C30H32F5N7O2 617.623000 |
HNUBSIFTMCDRBL-XNSWBKEBSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227094; PubChem:CID178290447
|
Local ready
Direct docking supported
|
|
E3L011030
BDB011030
|
US20260008770, Example 118
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc(C5(c6nncn6C)CC6(CC6)C5)ccn4)c(=O)c3c2)C1
|
C30H32F3N7O 563.628000 |
PKYQSVAOJVTZQH-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227095; PubChem:CID178290448
|
Local ready
Direct docking supported
|
|
E3L011031
BDB011031
|
BDBM227096
C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C6CC6)C[C@@H](C)C5)ccn4)c(=O)c3c2)C1
|
C31H34F3N7O 577.655000 |
ZEPLSBRQBWMJIJ-PRWCENSBSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227096
|
Local ready
Direct docking supported
|
|
E3L011032
BDB011032
|
BDBM227097
Cn1cnnc1[C@]1(c2ccnc(-n3cnc4c(C(F)(F)F)cc(CN5CCC6(CCO6)C5)cc4c3=O)c2)C[C@H](C)C1
|
C29H30F3N7O2 565.600000 |
OUAYZCXJOCBJOD-BPJZWELMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227097
|
Local ready
Direct docking supported
|
|
E3L011033
BDB011033
|
US20260008770, Example 78
CC1CC(c2ccnc(-n3cnc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C29H32F3N7O 551.617000 |
XADIXHNVHSRGOY-VURWPYGMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM227098; PubChem:CID178290411
|
Local ready
Direct docking supported
|
|
E3L011034
BDB011034
|
BDBM227099
C[C@@H]1CN(Cc2ccc3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)CCC1F
|
C29H33F2N7O2 549.626000 |
ZEHXETVKAAAXDS-KUGJXZKZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227099
|
Local ready
Direct docking supported
|
|
E3L011035
BDB011035
|
BDBM227100
C[C@H]1CCCN(Cc2ccc3ncn(-c4cc([C@]5(c6nncn6C(F)F)C[C@@H](C)C5)cc(OCF)n4)c(=O)c3c2)C1
|
C29H32F3N7O2 567.616000 |
WIUPWZSRPBGQBL-XFLNKKNVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM227100
|
Local ready
Direct docking supported
|
|
E3L011036
BDB011036
|
BDBM227335
COC(c1ccccc1)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H28ClN7O3 546.031000 |
WIHYOFCDDPRAMS-XEDXNJDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227335
|
Local ready
Direct docking supported
|
|
E3L011037
BDB011037
|
BDBM227391
COC(C)(c1ccccc1F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H29ClFN7O3 578.048000 |
NBICRJMLZQGIGZ-HBKKXGJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227391
|
Local ready
Direct docking supported
|
|
E3L011038
BDB011038
|
BDBM227393
COC(C)(c1csc(C)n1)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C27H29ClN8O3S 581.102000 |
DOZGJJHZDVZJFT-QLEMOQGCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227393
|
Local ready
Direct docking supported
|
|
E3L011039
BDB011039
|
BDBM227394
COC(C)(c1ccccn1)c1nc2nc(-c3nc(=O)o[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H30ClN7O3 560.058000 |
PVTGGEOCLYOQOH-KTYIESPOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227394
|
Local ready
Direct docking supported
|
|
E3L011040
BDB011040
|
BDBM227461
COC(C)(c1ccccn1)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H30ClN7O3 560.058000 |
RRASPEQACBMEGP-KTYIESPOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227461
|
Local ready
Direct docking supported
|