| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L011081
BDB011081
|
BDBM227694
COC(c1ccccc1C#N)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H27ClN8O3 571.041000 |
JFOYJPVPSYQZOO-CCERHYJRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227694
|
Local ready
Direct docking supported
|
|
E3L011082
BDB011082
|
BDBM227695
CC(F)(c1ccccc1C#N)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H26ClFN8O2 573.032000 |
FDACAMGQNQNUMA-HBKKXGJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227695
|
Local ready
Direct docking supported
|
|
E3L011083
BDB011083
|
BDBM227696
COC(C)(c1ccccc1C#N)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H29ClN8O3 585.068000 |
DEDPWBNKWRTFFJ-VVOUQJEZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227696
|
Local ready
Direct docking supported
|
|
E3L011084
BDB011084
|
BDBM227698
CC(c1ccccc1F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H27ClFN7O2 548.022000 |
SQSAMXGCQMFMKH-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227698
|
Local ready
Direct docking supported
|
|
E3L011085
BDB011085
|
BDBM227699
CC(c1ccccc1F)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H27ClFN7O2 548.022000 |
DVKNRKUUMOSOFN-XUWMOKQASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227699
|
Local ready
Direct docking supported
|
|
E3L011086
BDB011086
|
BDBM227700
CC(c1c(F)cccc1F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H26ClF2N7O2 566.012000 |
SZWNSAHLLWIFGC-CMTYHBQSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227700
|
Local ready
Direct docking supported
|
|
E3L011087
BDB011087
|
BDBM227701
CC(c1ccccc1C#N)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H27ClN8O2 555.042000 |
LXJWIHNSLAFLOE-KFZAHXERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227701
|
Local ready
Direct docking supported
|
|
E3L011088
BDB011088
|
BDBM227702
C[C@H]1CC[C@H](Cn2c(C3CC3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C24H25ClN6O2 464.957000 |
UENIPUGISPMNTR-HDJSIYSDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227702
|
Local ready
Direct docking supported
|
|
E3L011089
BDB011089
|
BDBM227703
C[C@H]1CC[C@H](Cn2c(C3CC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C24H25ClN6O2 464.957000 |
CBJKVQYTDDJFOX-HDJSIYSDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227703
|
Local ready
Direct docking supported
|
|
E3L011090
BDB011090
|
BDBM227704
CC(c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCOCC1
|
C28H33ClN6O3 537.064000 |
DYPGDMGEJGUBIG-KFZAHXERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227704
|
Local ready
Direct docking supported
|
|
E3L011091
BDB011091
|
BDBM227705
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-n4cc(Cl)ccc4=O)c32)CC1
|
C30H31ClN8O4 603.083000 |
FDQYFSVYQCKXBW-IPJJNNNSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227705
|
Local ready
Direct docking supported
|
|
E3L011092
BDB011092
|
BDBM227706
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(Oc4ccc(Cl)cn4)c32)CC1
|
C30H31ClN8O4 603.083000 |
XGFVDWNGXIYNFS-IPJJNNNSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227706
|
Local ready
Direct docking supported
|
|
E3L011093
BDB011093
|
BDBM227707
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4n[nH]c(=O)o4)nc(Oc4ccc(Cl)cn4)c32)CC1
|
C30H31ClN8O4 603.083000 |
ZVHQNNFJIKCTNS-IPJJNNNSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227707
|
Local ready
Direct docking supported
|
|
E3L011094
BDB011094
|
BDBM227708
C[C@@H]1COCCN1c1nc2nc(CC(=O)O)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H32ClN5O3 498.027000 |
UDKYQCJBOJTYEJ-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227708
|
Local ready
Direct docking supported
|
|
E3L011095
BDB011095
|
BDBM227709
CC1CN(c2nc(-c3noc(=O)[nH]3)nc3nc(N4CCOC[C@H]4c4ccccc4)n(C[C@H]4CC[C@H](C)CC4)c23)CCO1
|
C30H38N8O4 574.686000 |
DIIUGXSAATZGPT-HDVQDFIQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM227709
|
Local ready
Direct docking supported
|
|
E3L011096
BDB011096
|
BDBM227737
Cc1cccc(-c2nc3nc(C(=O)O)nc(N(C)CC(C)(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H28F3N5O2 511.548000 |
AJOXNQWBGDSJDL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM227737; PubChem:CID90318396
|
Local ready
Direct docking supported
|
|
E3L011097
BDB011097
|
BDBM227738
CCCCN(C)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C26H26F3N5O2 497.521000 |
RSNGROLHVQESAP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM227738; PubChem:CID90318033
|
Local ready
Direct docking supported
|
|
E3L011098
BDB011098
|
BDBM227739
Cc1cccc(-c2nc3nc(C(=O)O)nc(N4CCCC4C(C)C)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O2 523.559000 |
FVZMIQVDOOOLTF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM227739; PubChem:CID118558655
|
Local ready
Direct docking supported
|
|
E3L011099
BDB011099
|
BDBM227740
CCCC1CCCN1c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C28H28F3N5O2 523.559000 |
WDGURTMIBAGJPW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM227740; PubChem:CID90317999
|
Local ready
Direct docking supported
|
|
E3L011100
BDB011100
|
BDBM227741
CCC(C)CN(C)c1nc(C(=O)O)nc2nc(-c3cccc(C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12
|
C27H28F3N5O2 511.548000 |
HKDZBGHGWPTIQX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM227741; PubChem:CID90318469
|
Local ready
Direct docking supported
|