| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L001441
BDB001441
|
1,4-Benzodiazepine-2,5-dione, 12h
COCCOCCN1C(=O)[C@@H](c2ccc(Cl)cc2)N([C@@H](C)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C28H27Cl2IN2O4 653.344000 |
MDTAPSOLFJDBQB-HFJWLAOPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31311; PubChem:CID44176184
|
Local ready
Direct docking supported
|
|
E3L001442
BDB001442
|
1,4-Benzodiazepine-2,5-dione, 12j
CC#Cc1ccc2c(c1)C(=O)N([C@H](C)c1ccc(Cl)cc1N)[C@@H](c1ccc(Cl)cc1)C(=O)N2CCN1CCOCC1
|
C32H32Cl2N4O3 591.539000 |
LQZUTIMEANELKZ-DFXYEROKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31313; PubChem:CID11952735
|
Local ready
Direct docking supported
|
|
E3L001443
BDB001443
|
BDBM31314
C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCCN2CCN(C)CC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C31H34Cl2IN5O2 706.456000 |
NUKCQDDVORQLDB-OLILMLBXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31314; PubChem:CID11571200
|
Local ready
Direct docking supported
|
|
E3L001444
BDB001444
|
1,4-Benzodiazepine-2,5-dione, 12l
C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CC(=O)N2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H26Cl2IN3O4 678.354000 |
DFMCKWBGWKZCKJ-CLYVBNDRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31315; PubChem:CID21060011
|
Local ready
Direct docking supported
|
|
E3L001445
BDB001445
|
1,4-Benzodiazepine-2,5-dione, 12m
C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CC(=O)N2CCNCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H28Cl2IN5O3 692.385000 |
NUGGDLILWIMASB-CRYYWNKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31316; PubChem:CID11952566
|
Local ready
Direct docking supported
|
|
E3L001446
BDB001446
|
1,4-Benzodiazepine-2,5-dione antagonist, 2
O=C(O)C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
|
C24H17Cl2IN2O4 595.220000 |
UHDVYHWPJKKLPO-IRLDBZIGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31318; PubChem:CID44176185
|
Local ready
Direct docking supported
|
|
E3L001447
BDB001447
|
1,4-Benzodiazepine-2,5-dione antagonist, 3
O=C(NCCO)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
|
C25H20Cl2IN3O4 624.262000 |
RWPFTTITCVNHHF-VXKWHMMOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31319; PubChem:CID44176186
|
Local ready
Direct docking supported
|
|
E3L001448
BDB001448
|
1,4-Benzodiazepine-2,5-dione antagonist, 4
O=C(O)CCNC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
|
C26H20Cl2IN3O5 652.272000 |
MXZSBXTUYOFCRV-GOTSBHOMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31320; PubChem:CID44176187
|
Local ready
Direct docking supported
|
|
E3L001449
BDB001449
|
1,4-Benzodiazepine-2,5-dione antagonist, 5
O=C(O)CCCCNC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
|
C28H24Cl2IN3O5 680.326000 |
ANYUCRJJKHLZON-DQEYMECFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31321; PubChem:CID44176188
|
Local ready
Direct docking supported
|
|
E3L001450
BDB001450
|
1,4-Benzodiazepine-2,5-dione antagonist, 6
CN(C)CCNC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2NC(=O)[C@@H]1c1ccc(Cl)cc1
|
C27H25Cl2IN4O3 651.332000 |
PUQZWAZCZZGVMG-ZEQRLZLVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31322; PubChem:CID44176189
|
Local ready
Direct docking supported
|
|
E3L001451
BDB001451
|
1,4-Benzodiazepine-2,5-dione antagonist, 8
CN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C24H17Cl2IN2O4 595.220000 |
NFQDVKDBCGSJQN-SFTDATJTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31323; PubChem:CID44176190
|
Local ready
Direct docking supported
|
|
E3L001452
BDB001452
|
1,4-Benzodiazepine-2,5-dione antagonist, 9
CNC(=O)CN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C26H20Cl2IN3O5 652.272000 |
IRUUIIXRURRPCS-GOTSBHOMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31324; PubChem:CID44176191
|
Local ready
Direct docking supported
|
|
E3L001453
BDB001453
|
1,4-Benzodiazepine-2,5-dione antagonist, 10
O=C(O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(Cc2ccncc2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H20Cl2IN3O4 672.306000 |
GCTUOYWCMFLXSC-UIOOFZCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31325; PubChem:CID44176192
|
Local ready
Direct docking supported
|
|
E3L001454
BDB001454
|
1,4-Benzodiazepine-2,5-dione antagonist, 11
O=C(O)CN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C25H17Cl2IN2O6 639.229000 |
NGQMFSXASTVFRU-VXKWHMMOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31326; PubChem:CID44176193
|
Local ready
Direct docking supported
|
|
E3L001455
BDB001455
|
1,4-Benzodiazepine-2,5-dione antagonist, 12
O=C(O)CCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C26H19Cl2IN2O6 653.256000 |
FELRJPIAMHMGEQ-GOTSBHOMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31327; PubChem:CID44176194
|
Local ready
Direct docking supported
|
|
E3L001456
BDB001456
|
1,4-Benzodiazepine-2,5-dione antagonist, 13
O=C(O)CCCCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C28H23Cl2IN2O6 681.310000 |
JFDPWVMFHFOLFW-DQEYMECFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31328; PubChem:CID44176195
|
Local ready
Direct docking supported
|
|
E3L001457
BDB001457
|
1,4-Benzodiazepine-2,5-dione antagonist, 14
CN(C)CCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C27H24Cl2IN3O4 652.316000 |
CHUHVISKSKMVCI-ZEQRLZLVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31329; PubChem:CID44176196
|
Local ready
Direct docking supported
|
|
E3L001458
BDB001458
|
1,4-Benzodiazepine-2,5-dione antagonist, 15
COC(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H25Cl2IN2O6 695.337000 |
KXKHVDIJDBRCHO-UIOOFZCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31330; PubChem:CID44176197
|
Local ready
Direct docking supported
|
|
E3L001459
BDB001459
|
1,4-Benzodiazepine-2,5-dione antagonist, 16
CCN(CC)C(=O)[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C32H32Cl2IN3O5 736.434000 |
MHOPTQKTBICWMN-VMPREFPWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31331; PubChem:CID44176198
|
Local ready
Direct docking supported
|
|
E3L001460
BDB001460
|
1,4-Benzodiazepine-2,5-dione antagonist, 17
O=C(O)CCCCN1C(=O)[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C27H23Cl2IN2O4 637.301000 |
RIRQVBKIUJQHPL-VWLOTQADSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31332; PubChem:CID44176199
|
Local ready
Direct docking supported
|