| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L001421
BDB001421
|
1,4-Benzodiazepine-2,5-dione scaffold, 21
COCCOCCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C)c2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21
|
C28H28Cl2IN3O4 668.359000 |
RTYOJEHILRDOMQ-QUGAMOGWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31289; PubChem:CID9917797
|
Local ready
Direct docking supported
|
|
E3L001422
BDB001422
|
1,4-Benzodiazepine-2,5-dione scaffold, 49
COCCOCCN1C(=O)[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)cc2O)C(=O)c2cc(I)ccc21
|
C27H25Cl2IN2O5 655.316000 |
ZMHHWPQWCVSKMV-VWLOTQADSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31290; PubChem:CID44176173
|
Local ready
Direct docking supported
|
|
E3L001423
BDB001423
|
1,4-Benzodiazepine-2,5-dione scaffold, 50
C=CCOc1cc(Cl)ccc1CN1C(=O)c2cc(I)ccc2N(CCOCCOC)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C30H29Cl2IN2O5 695.381000 |
ROSFDQQEKJVLGC-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31291; PubChem:CID44176174
|
Local ready
Direct docking supported
|
|
E3L001424
BDB001424
|
1,4-Benzodiazepine-2,5-dione scaffold, 51
COCCOCCN1C(=O)[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)nc2N)C(=O)c2cc(I)ccc21
|
C26H25Cl2IN4O4 655.320000 |
AOFJFROKSQUNCA-QHCPKHFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31292; PubChem:CID44176175
|
Local ready
Direct docking supported
|
|
E3L001425
BDB001425
|
1,4-Benzodiazepine-2,5-dione scaffold, 22
C[C@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H29Cl2IN4O3 679.386000 |
TXTIZPFXYRRDES-CLYVBNDRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31293; PubChem:CID11952782
|
Local ready
Direct docking supported
|
|
E3L001426
BDB001426
|
1,4-Benzodiazepine-2,5-dione scaffold, 23
Nc1cc(Cl)ccc1CN1C(=O)c2cc(I)ccc2N(CCCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H29Cl2IN4O3 679.386000 |
DIRPNNUWQMTLTK-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31294; PubChem:CID44176176
|
Local ready
Direct docking supported
|
|
E3L001427
BDB001427
|
1,4-Benzodiazepine-2,5-dione scaffold, 27
C[C@H](c1cc(F)c(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H28Cl2FIN4O3 697.376000 |
RETYZFIEVMZHPB-CRYYWNKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31295; PubChem:CID11953136
|
Local ready
Direct docking supported
|
|
E3L001428
BDB001428
|
1,4-Benzodiazepine-2,5-dione scaffold, 28
C[C@H](c1cc(O)c(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H29Cl2IN4O4 695.385000 |
CIPUXOASBLBAEP-CRYYWNKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31296; PubChem:CID11953137
|
Local ready
Direct docking supported
|
|
E3L001429
BDB001429
|
1,4-Benzodiazepine-2,5-dione scaffold, 26
O=C1[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)cc2F)C(=O)c2cc(I)ccc2N1CCN1CCOCC1
|
C28H25Cl2FIN3O3 668.334000 |
SZUZMYZODLFEHY-SANMLTNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31297; PubChem:CID44176177
|
Local ready
Direct docking supported
|
|
E3L001430
BDB001430
|
1,4-Benzodiazepine-2,5-dione scaffold, 24
Nc1cc(C2(N3C(=O)c4cc(I)ccc4N(CCN4CCOCC4)C(=O)[C@@H]3c3ccc(Cl)cc3)CC2)ccc1Cl
|
C30H29Cl2IN4O3 691.397000 |
SKDYLCZPJKRLHY-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31298; PubChem:CID44176178
|
Local ready
Direct docking supported
|
|
E3L001431
BDB001431
|
1,4-Benzodiazepine-2,5-dione scaffold, 25
Cc1cc(Cl)ccc1CN1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H28Cl2IN3O3 664.371000 |
BWJZWGVPPXHFLK-MHZLTWQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31299; PubChem:CID44176179
|
Local ready
Direct docking supported
|
|
E3L001432
BDB001432
|
1,4-Benzodiazepine-2,5-dione scaffold, 29
CN(C)CCCCN1C(=O)[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21
|
C28H29Cl2IN4O2 651.376000 |
JRZMBZBPVQMTFT-SANMLTNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31300; PubChem:CID44176180
|
Local ready
Direct docking supported
|
|
E3L001433
BDB001433
|
1,4-Benzodiazepine-2,5-dione scaffold, 31
CN(C)CCCN1C(=O)[C@H](c2ccc(Cl)cc2)N(Cc2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21
|
C27H27Cl2IN4O2 637.349000 |
CUXYJJOQGJZCMF-VWLOTQADSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31301; PubChem:CID44176181
|
Local ready
Direct docking supported
|
|
E3L001434
BDB001434
|
1,4-Benzodiazepine-2,5-dione scaffold, 30
CN1CCN(CCCN2C(=O)[C@H](c3ccc(Cl)cc3)N(Cc3ccc(Cl)cc3N)C(=O)c3cc(I)ccc32)CC1
|
C30H32Cl2IN5O2 692.429000 |
SZOYOLFYNBXVHW-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31302; PubChem:CID44176182
|
Local ready
Direct docking supported
|
|
E3L001435
BDB001435
|
1,4-Benzodiazepine-2,5-dione scaffold, 32
CN1CCN(CCCCN2C(=O)[C@H](c3ccc(Cl)cc3)N(Cc3ccc(Cl)cc3N)C(=O)c3cc(I)ccc32)CC1
|
C31H34Cl2IN5O2 706.456000 |
MUHZTXDQFRVJAS-LJAQVGFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31303; PubChem:CID44176183
|
Local ready
Direct docking supported
|
|
E3L001436
BDB001436
|
BDBM31305
C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C28H25Cl2IN2O4 651.328000 |
VLOPNYYNACVDTC-QUGAMOGWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31305; PubChem:CID11952815
|
Local ready
Direct docking supported
|
|
E3L001437
BDB001437
|
1,4-Benzodiazepine-2,5-dione, 12c
C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@@H]1c1ccc(Cl)cc1
|
C29H28Cl2IN3O3 664.371000 |
ATPRYWVAPFXDLB-WINIVTDRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31306; PubChem:CID21060012
|
Local ready
Direct docking supported
|
|
E3L001438
BDB001438
|
1,4-Benzodiazepine-2,5-dione, 12d
C[C@H](c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@H]1c1ccc(Cl)cc1
|
C29H28Cl2IN3O3 664.371000 |
ATPRYWVAPFXDLB-XHCCPWGMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31307; PubChem:CID21060006
|
Local ready
Direct docking supported
|
|
E3L001439
BDB001439
|
1,4-Benzodiazepine-2,5-dione, 12f
C[C@@H](c1ccc(Cl)cc1N)N1C(=O)c2cc(I)ccc2N(CCN2CCOCC2)C(=O)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2IN4O3 679.386000 |
TXTIZPFXYRRDES-XRHLQHRESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31309; PubChem:CID11952784
|
Local ready
Direct docking supported
|
|
E3L001440
BDB001440
|
1,4-Benzodiazepine-2,5-dione, 12g
COCCOCCN1C(=O)[C@H](c2ccc(Cl)cc2)N([C@H](C)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21
|
C28H27Cl2IN2O4 653.344000 |
MDTAPSOLFJDBQB-DWXRJYCRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM31310; PubChem:CID21060010
|
Local ready
Direct docking supported
|