| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023641
BDB023641
|
BDBM535783
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OC[C@@H](C)O)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
|
C32H34ClFN4O5 609.098000 |
MFJXVQCJOJBJSN-ZDDMJVHESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM535783
|
Local ready
Direct docking supported
|
|
E3L023642
BDB023642
|
US11236047, Example 524
CCC(O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C31H34Cl2FN5O4 630.548000 |
DOOLEYVFQATQEL-JOINGXBXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535785; PubChem:CID135282089
|
Local ready
Direct docking supported
|
|
E3L023643
BDB023643
|
US11236047, Example 526
CCC(O)(CN1CC[C@@H](O)C1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C31H33Cl2FN4O5 631.532000 |
KKQVYJKFFYTVGQ-VPAANPLTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535786; PubChem:CID137498040
|
Local ready
Direct docking supported
|
|
E3L023644
BDB023644
|
US11236047, Example 528
CCC(O)(CN(C)C)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C29H31Cl2FN4O4 589.495000 |
IMWIKKNQOUEPQC-MVAUJPHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535788; PubChem:CID135282169
|
Local ready
Direct docking supported
|
|
E3L023645
BDB023645
|
US11236047, Example 530
CCC(O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1
|
C29H32Cl2FN5O4 604.510000 |
ISTMKLDBKUEYGB-YPJJGMIRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535789; PubChem:CID135282086
|
Local ready
Direct docking supported
|
|
E3L023646
BDB023646
|
US11236047, Example 532
CCC(O)(CN1CCN(C)CC1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1
|
C30H34Cl2FN5O4 618.537000 |
OVXCRCRSYWAUFQ-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535790; PubChem:CID135282348
|
Local ready
Direct docking supported
|
|
E3L023647
BDB023647
|
US11236047, Example 534
CCC(O)(CN1CCN(C)CC1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCC1(C#N)CC1)c1ccc(Cl)cc1
|
C33H35Cl2FN6O3 653.586000 |
GJZOHGAQYXUXCM-ZHZZGXISSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535791; PubChem:CID135282707
|
Local ready
Direct docking supported
|
|
E3L023648
BDB023648
|
US11236047, Example 522
CCC(O)(CN1CCN(C)CC1)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C32H36Cl2FN5O4 644.575000 |
UWEXKSFZEKXFGI-LOKXLOOWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535792; PubChem:CID135282597
|
Local ready
Direct docking supported
|
|
E3L023649
BDB023649
|
US11236047, Example 553
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(C)CC1
|
C29H31Cl2FN4O3 573.496000 |
RXWFSQUACIFPTB-URLMMPGGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535793; PubChem:CID135283031
|
Local ready
Direct docking supported
|
|
E3L023650
BDB023650
|
US11236047, Example 559
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1)C1CCN(C)CC1
|
C30H33Cl2FN4O4 603.522000 |
MTVISPOCUBWYQU-XZWHSSHBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535794; PubChem:CID135282534
|
Local ready
Direct docking supported
|
|
E3L023651
BDB023651
|
US11236047, Example 562
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OC[C@@H](C)O)c1ccc(Cl)cc1)C1CCN(C)CC1
|
C31H35Cl2FN4O4 617.549000 |
VBOLIJYMGSQRFX-MUMCFHHVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535795; PubChem:CID135282478
|
Local ready
Direct docking supported
|
|
E3L023652
BDB023652
|
US11236047, Example 550
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(CCO)CC1
|
C30H33Cl2FN4O4 603.522000 |
JRFKQIQQIAJEPR-XZWHSSHBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535796; PubChem:CID135282931
|
Local ready
Direct docking supported
|
|
E3L023653
BDB023653
|
US11236047, Example 513
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C28H26ClFN4O4 536.991000 |
XJGKRRJKFHLFEF-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535797; PubChem:CID163407656
|
Local ready
Direct docking supported
|
|
E3L023654
BDB023654
|
US11236047, Example 577
CCC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C29H28ClFN4O4 551.018000 |
XFDBIZMVEPJQIF-ZBAATNBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535798; PubChem:CID163407657
|
Local ready
Direct docking supported
|
|
E3L023655
BDB023655
|
US11236047, Example 491
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cc1OC)[C@@]2(OCCO)c1ccc(Cl)cc1)c1cn(C)cn1
|
C30H29Cl2FN4O5 615.489000 |
QTAAEQKGSBEGOC-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535799; PubChem:CID137498015
|
Local ready
Direct docking supported
|
|
E3L023656
BDB023656
|
US11236047, Example 578
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C28H27Cl2F2N3O5 594.442000 |
WCODONRZQFMBLE-SVNIRARHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535800; PubChem:CID135283143
|
Local ready
Direct docking supported
|
|
E3L023657
BDB023657
|
8-Methyl-6-oxo-2,7-diazaspiro[4.4]nonane-2-carbonitrile
CC1C[C@]2(CCN(C#N)C2)C(=O)N1
|
C9H13N3O 179.223000 |
QJSGPSYFYHOZNH-NETXQHHPSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535802; PubChem:CID163407658
|
Local ready
Direct docking supported
|
|
E3L023658
BDB023658
|
US11236092, Example 83
CC1C[C@@]2(CCN(C#N)C2)C(=O)N1
|
C9H13N3O 179.223000 |
QJSGPSYFYHOZNH-NHSZFOGYSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535803; PubChem:CID163407659
|
Local ready
Direct docking supported
|
|
E3L023659
BDB023659
|
US11236092, Example 84
N#CN1CC[C@@]2(CC(c3ccccc3)NC2=O)C1
|
C14H15N3O 241.294000 |
NSGFJJKNIQRTHW-TYZXPVIJSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535804; PubChem:CID163407660
|
Local ready
Direct docking supported
|
|
E3L023660
BDB023660
|
US11236047, Example 515
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C)nc1C(=O)O)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C31H31ClF2N2O6 601.046000 |
XSHRXYPCIVWDNP-FIRIVFDPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535805; PubChem:CID135282501
|
Local ready
Direct docking supported
|