| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023621
BDB023621
|
US11236047, Example 426
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(O[C@@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C32H29ClFN5O4 602.066000 |
XHCNIWPQGUYHCF-CYMJYBMMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535756; PubChem:CID137497987
|
Local ready
Direct docking supported
|
|
E3L023622
BDB023622
|
US11236047, Example 438
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC[C@@H](C)O)c1ccc(Cl)cc1)c1cn(C)cn1
|
C31H29ClFN5O4 590.055000 |
YDFBJRFMXYRLJM-VSVGVIERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535757; PubChem:CID135282353
|
Local ready
Direct docking supported
|
|
E3L023623
BDB023623
|
US11236047, Example 440
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C33H31ClFN5O4 616.093000 |
WNVLDRQSRWIKSR-ZHZZGXISSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535759; PubChem:CID135282541
|
Local ready
Direct docking supported
|
|
E3L023624
BDB023624
|
US11236047, Example 441
Cn1cc(C(O)(CF)c2ccc3c(c2)C(=O)N(Cc2ccc(C#N)cn2)[C@@]3(O[C@H]2CCOC2)c2ccc(Cl)cc2)cn1
|
C31H27ClFN5O4 588.039000 |
YVIAFQAKHVRQOG-JCHZNZEOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535760; PubChem:CID137513400
|
Local ready
Direct docking supported
|
|
E3L023625
BDB023625
|
US11236047, Example 451
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)C(=O)NC3CCN(C)CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H32Cl2N4O4 583.516000 |
WCTSDTWABMUYDH-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535762; PubChem:CID135282606
|
Local ready
Direct docking supported
|
|
E3L023626
BDB023626
|
US11236092, Example 44
N#CN1CCC2(Cc3cc(-c4ccc(F)cc4)ccc3NC2=O)C1
|
C19H16FN3O 321.355000 |
TWRBYEBVRGHILJ-UHFFFAOYSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535764; PubChem:CID137378661
|
Local ready
Direct docking supported
|
|
E3L023627
BDB023627
|
US11236047, Example 453
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)C(=O)Nc3cnn(C)c3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H25Cl2N5O4 566.445000 |
LDOZVXKNXVTXJP-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535765; PubChem:CID135282732
|
Local ready
Direct docking supported
|
|
E3L023628
BDB023628
|
US11236047, Example 456
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)C(=O)NC3CN(C)C3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H28Cl2N4O4 555.462000 |
KCMILRVZTKUFMT-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535767; PubChem:CID135282944
|
Local ready
Direct docking supported
|
|
E3L023629
BDB023629
|
US11236047, Example 459
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)C3CCN(CC(=O)O)CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H30Cl2FN3O5 602.490000 |
LEBZOJICUSODDT-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535768; PubChem:CID135283062
|
Local ready
Direct docking supported
|
|
E3L023630
BDB023630
|
US11236047, Example 460
Cc1cnc(CN2C(=O)c3cc(C(C)(C)O)ccc3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)cn1
|
C28H30ClN3O4 508.018000 |
ZWMXXGFGENSWSG-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535769; PubChem:CID135282582
|
Local ready
Direct docking supported
|
|
E3L023631
BDB023631
|
US11236047, Example 461
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OC1CCC(O)C1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C32H30ClFN6O4 617.081000 |
SIFDSZDGKUGJTO-NQSPBDJXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535770; PubChem:CID137512742
|
Local ready
Direct docking supported
|
|
E3L023632
BDB023632
|
BDBM535771
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1C[C@@H](O)C1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C30H28Cl2FN5O4 612.489000 |
PUEPUEVWUMLLPQ-VELDXABHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM535771
|
Local ready
Direct docking supported
|
|
E3L023633
BDB023633
|
US11236047, Example 466
C=C(CO)CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(O)(CC)c3cn(C)cn3)cc2C(=O)N1Cc1ccc(C#N)cn1
|
C32H29ClFN5O4 602.066000 |
OPDQOJKZFYMCJQ-IADGFXSZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535772; PubChem:CID135282656
|
Local ready
Direct docking supported
|
|
E3L023634
BDB023634
|
US11236047, Example 468
Cn1cnc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ncc(C#N)cn2)[C@@]3(OCC2(F)COC2)c2ccc(Cl)cc2)c1
|
C30H25ClF2N6O4 607.017000 |
CCIHRCXDXNUEJC-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535773; PubChem:CID135282979
|
Local ready
Direct docking supported
|
|
E3L023635
BDB023635
|
US11236047, Example 470
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OCC1(F)COC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C31H27ClF2N6O4 621.044000 |
DGWQHGBOIMCQFW-NLIBRCFJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535774; PubChem:CID135282631
|
Local ready
Direct docking supported
|
|
E3L023636
BDB023636
|
BDBM535776
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(O[C@H]1C[C@H](CO)C1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C32H30ClFN6O4 617.081000 |
LWGPMDOLLXQRCR-QFNVXXLUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM535776
|
Local ready
Direct docking supported
|
|
E3L023637
BDB023637
|
US11236047, Example 493
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C30H29Cl2F2N3O5 620.480000 |
YHOMQLQCVYYRQC-GQMPWXHXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535777; PubChem:CID135282598
|
Local ready
Direct docking supported
|
|
E3L023638
BDB023638
|
BDBM535780
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(O[C@H]1C[C@@H](O)C1)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
|
C31H32Cl2FN3O5 616.517000 |
IASXKSYUAIXXDE-NWFWUAPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM535780
|
Local ready
Direct docking supported
|
|
E3L023639
BDB023639
|
US11236047, Example 501
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C29H29Cl2F2N3O5 608.469000 |
CPLOBKSITDKJJL-FQLXRVMXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535781; PubChem:CID137497958
|
Local ready
Direct docking supported
|
|
E3L023640
BDB023640
|
US11236047, Example 509
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(C#N)cn1)[C@@]2(OCCO)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C30H29ClF2N4O5 599.034000 |
FRAVIXIBGFVNQU-LOYHVIPDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535782; PubChem:CID135282723
|
Local ready
Direct docking supported
|