| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023581
BDB023581
|
US11236047, Example 418
CC(C)(O)c1cc(F)c2c(c1)C(=O)N([C@@H](CO)c1ccc(Cl)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C29H29Cl2FN2O5 575.464000 |
OUIQFUHIJYJICV-PWUYWRBVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535451; PubChem:CID135283138
|
Local ready
Direct docking supported
|
|
E3L023582
BDB023582
|
US11236047, Example 408
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)c[n+]2[O-])[C@@]3(OCC2(C#N)CC2)c2ccc(Cl)cc2)cn1
|
C31H26Cl2FN5O4 622.484000 |
PPRQBTGGPVRJIV-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535452; PubChem:CID135282625
|
Local ready
Direct docking supported
|
|
E3L023583
BDB023583
|
US11236047, Example 409
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)c[n+]2[O-])[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)cn1
|
C30H27Cl2FN4O5 613.473000 |
XFMUFTRUWONRPH-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535453; PubChem:CID137497969
|
Local ready
Direct docking supported
|
|
E3L023584
BDB023584
|
US11236047, Example 396
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(O)CC1)c1ccc(Cl)cc1)c1ncccn1
|
C30H25Cl2FN4O4 595.458000 |
ZDTDRSMIUYSHRA-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535454; PubChem:CID135282714
|
Local ready
Direct docking supported
|
|
E3L023585
BDB023585
|
US11236047, Example 348
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ncc(Cl)cn2)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)cn1
|
C30H28Cl2FN5O4 612.489000 |
AUSFXZCNGFOETO-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535455; PubChem:CID135282623
|
Local ready
Direct docking supported
|
|
E3L023586
BDB023586
|
US11236047, Example 341
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(C#N)cn2)[C@@]3(OCC2(O)CC2)c2ccc(Cl)cc2)cn1
|
C31H27ClFN5O4 588.039000 |
DOGJTGROPSWBRY-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535456; PubChem:CID135282545
|
Local ready
Direct docking supported
|
|
E3L023587
BDB023587
|
US11236047, Example 422
CC(=O)N1CCC(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ncc(Cl)cn2)[C@@]3(OCCO)c2ccc(Cl)cc2)CC1
|
C30H31Cl2FN4O5 617.505000 |
OEMUXZKPZLMBBQ-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535458; PubChem:CID135283065
|
Local ready
Direct docking supported
|
|
E3L023588
BDB023588
|
US11236047, Example 404
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCC1
|
C30H29Cl2FN4O4 599.490000 |
BYBQBCBTNQMUTJ-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535459; PubChem:CID135282813
|
Local ready
Direct docking supported
|
|
E3L023589
BDB023589
|
BDBM535460
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(C#N)cn2)[C@@]3(O[C@H]2C[C@@H](O)C2)c2ccc(Cl)cc2)cn1
|
C31H27ClFN5O4 588.039000 |
PLLUZPZNYWOMRY-MRRBAKFHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM535460
|
Local ready
Direct docking supported
|
|
E3L023590
BDB023590
|
US11236047, Example 410
CCC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H29ClFN3O4 550.030000 |
LCMLWYJDMGQUES-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535461; PubChem:CID135282513
|
Local ready
Direct docking supported
|
|
E3L023591
BDB023591
|
US11236047, Example 412
C=CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H27ClFN3O4 548.014000 |
ZUYUPGSFWPOBQN-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535722; PubChem:CID135282590
|
Local ready
Direct docking supported
|
|
E3L023592
BDB023592
|
US11236047, Example 398
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)[C@@]2(OCC1(O)CC1)c1ccc(Cl)cc1)C1CCS(=O)(=O)CC1
|
C30H30Cl2FN3O6S 650.556000 |
UQSZGPZMUWVMKS-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535724; PubChem:CID137497992
|
Local ready
Direct docking supported
|
|
E3L023593
BDB023593
|
US11236047, Example 423
CN1CCC(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ncc(Cl)cn2)[C@@]3(O[C@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C31H33Cl2FN4O4 615.533000 |
CXQPNLBJOBIXBV-JOINGXBXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535725; PubChem:CID135282519
|
Local ready
Direct docking supported
|
|
E3L023594
BDB023594
|
US11236092, Example 6
N#CN1CC[C@]2(Cc3cc(-c4ccc(-c5ccccc5)cc4)ccc3NC2=O)C1
|
C25H21N3O 379.463000 |
NGRBLYJMHHFRMM-VWLOTQADSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535726; PubChem:CID163407649
|
Local ready
Direct docking supported
|
|
E3L023595
BDB023595
|
US11236092, Example 7
N#CN1CC[C@]2(Cc3cc(-c4ccc(OCc5ccccc5)cc4)ccc3NC2=O)C1
|
C26H23N3O2 409.489000 |
ZEDBVTZEWNUZIU-SANMLTNESA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535727; PubChem:CID163407650
|
Local ready
Direct docking supported
|
|
E3L023596
BDB023596
|
US11236092, Example 8
Cc1ccc(F)c(-c2ccc3c(c2)C[C@]2(CCN(C#N)C2)C(=O)N3)c1
|
C20H18FN3O 335.382000 |
LMBLJDUGOVJVCN-FQEVSTJZSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535728; PubChem:CID163407651
|
Local ready
Direct docking supported
|
|
E3L023597
BDB023597
|
US11236092, Example 9
N#Cc1cccc(-c2ccc3c(c2)C[C@]2(CCN(C#N)C2)C(=O)N3)c1
|
C20H16N4O 328.375000 |
IQIHWZWUMFLBRA-FQEVSTJZSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535729; PubChem:CID163407652
|
Local ready
Direct docking supported
|
|
E3L023598
BDB023598
|
US11236092, Example 10
Cn1nccc1-c1ccc2c(c1)C[C@]1(CCN(C#N)C1)C(=O)N2
|
C17H17N5O 307.357000 |
FEGQVSBVTHPTQK-KRWDZBQOSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535730; PubChem:CID163407653
|
Local ready
Direct docking supported
|
|
E3L023599
BDB023599
|
US11236092, Example 11
N#CN1CC[C@]2(Cc3cc(-c4cccc(Oc5ccccc5)c4)ccc3NC2=O)C1
|
C25H21N3O2 395.462000 |
IPMLHQOYSBJXCR-VWLOTQADSA-N | Q6GQQ9 | OTU domain-containing protein 7B |
BindingDB, PubChem
BindingDB:BDBM535731; PubChem:CID163407654
|
Local ready
Direct docking supported
|
|
E3L023600
BDB023600
|
US11236047, Example 416
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)C(F)(F)F
|
C29H24ClF4N3O4 589.973000 |
FNRDUUKOZHITMC-SVNIRARHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535732; PubChem:CID137497995
|
Local ready
Direct docking supported
|