| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L026761
BDB026761
|
US11407721, Example 49
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2cccc(C#N)c2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H26Cl2N2O4 537.443000 |
SPYIFURQACUIAM-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562802; PubChem:CID86282599
|
Local ready
Direct docking supported
|
|
E3L026762
BDB026762
|
US11407721, Example 50
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2cccc(S(C)(=O)=O)c2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2NO6S 590.525000 |
LSNLEJWOTADEBZ-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562803; PubChem:CID86282467
|
Local ready
Direct docking supported
|
|
E3L026763
BDB026763
|
US11407721, Example 51
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccccc2S(C)(=O)=O)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2NO6S 590.525000 |
PEUMHKJNNDMFQQ-PTJMHOJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562804; PubChem:CID86282739
|
Local ready
Direct docking supported
|
|
E3L026764
BDB026764
|
US11407721, Example 52
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(F)cc2S(C)(=O)=O)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H28Cl2FNO6S 608.515000 |
IVUMCPDLSMRPHW-PTJMHOJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562805; PubChem:CID86282740
|
Local ready
Direct docking supported
|
|
E3L026765
BDB026765
|
US11407721, Example 53
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(S(C)(=O)=O)c(F)c2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H28Cl2FNO6S 608.515000 |
AHQBKWGBBRACRW-PTJMHOJZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562806; PubChem:CID86282741
|
Local ready
Direct docking supported
|
|
E3L026766
BDB026766
|
US11407721, Example 54
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(S(C)(=O)=O)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2NO6S 590.525000 |
SOTSYTXAFGARSV-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562807; PubChem:CID86282742
|
Local ready
Direct docking supported
|
|
E3L026767
BDB026767
|
US11407721, Example 55
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(S(C)(=O)=O)cc2C#N)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C30H28Cl2N2O6S 615.535000 |
WEBCGFZJJBTPNT-GCFVYEKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562808; PubChem:CID90371903
|
Local ready
Direct docking supported
|
|
E3L026768
BDB026768
|
US11407721, Example 56
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(S(=O)(=O)C(F)(F)F)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H26Cl2F3NO6S 644.495000 |
YVJUKVSHQAHNBQ-ZJSPYRCASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562809; PubChem:CID86280698
|
Local ready
Direct docking supported
|
|
E3L026769
BDB026769
|
US11407721, Example 57
CCC[C@H](C(=O)O)N1C(=O)[C@H](CCCN2CCOCC2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C28H34Cl2N2O5 549.495000 |
NGKDSMRXYILHBJ-ZJSPYRCASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562810; PubChem:CID86280699
|
Local ready
Direct docking supported
|
|
E3L026770
BDB026770
|
US11407721, Example 58
O=C1[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)N1c1ccnc(Cl)c1
|
C28H20Cl3FN2O2 541.837000 |
KDMZQPXBRXKOKS-FXVJXKIMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562811; PubChem:CID86280701
|
Local ready
Direct docking supported
|
|
E3L026771
BDB026771
|
US11407721, Example 59
O=C1[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)N1c1cccnc1
|
C28H21Cl2FN2O2 507.392000 |
NKGNWIMUMHTIQK-KWXIBIRDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562812; PubChem:CID165414772
|
Local ready
Direct docking supported
|
|
E3L026772
BDB026772
|
US11407721, Example 60
O=C1[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)N1c1cn[nH]c1
|
C26H20Cl2FN3O2 496.369000 |
GAQCTUBQELXKFM-DSNGMDLFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562813; PubChem:CID118623002
|
Local ready
Direct docking supported
|
|
E3L026773
BDB026773
|
US11407721, Example 61
O=C1[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)N1c1ccncc1
|
C28H21Cl2FN2O2 507.392000 |
VPGKHHKAWPXNLG-KWXIBIRDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562814; PubChem:CID90357020
|
Local ready
Direct docking supported
|
|
E3L026774
BDB026774
|
US11407721, Example 62
CS(=O)(=O)c1ccc(C[C@H]2O[C@H](c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N(c3cccnc3)C2=O)cc1
|
C29H24Cl2N2O4S 567.494000 |
ZOHISOPDHUSNHZ-QBYFTLAFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562815; PubChem:CID159929572
|
Local ready
Direct docking supported
|
|
E3L026775
BDB026775
|
US11407721, Example 63
CS(=O)(=O)c1ccc(C[C@H]2O[C@H](c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N(c3cccnc3)C2=O)c(F)c1
|
C29H23Cl2FN2O4S 585.484000 |
FPKXWYRDEQIPKH-QBYFTLAFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562816; PubChem:CID158387004
|
Local ready
Direct docking supported
|
|
E3L026776
BDB026776
|
US11407721, Example 64
CN1CCN(C(=O)C[C@H]2O[C@H](c3cccc(Cl)c3)[C@H](c3ccc(Cl)cc3)N(CC3CC3)C2=O)CC1
|
C27H31Cl2N3O3 516.469000 |
DMOPFPDBKUOWQW-DMTNHVFBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562817; PubChem:CID118622876
|
Local ready
Direct docking supported
|
|
E3L026777
BDB026777
|
US11407721, Example 65
CCC[C@@H](C(N)=O)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@@H]1c1ccc(Cl)cc1
|
C23H24Cl2N2O5 479.360000 |
QDILNQYTSNQECW-IZZBFERCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562818; PubChem:CID90356899
|
Local ready
Direct docking supported
|
|
E3L026778
BDB026778
|
US11407721, Example 66
CCCC(C#N)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@@H]1c1ccc(Cl)cc1
|
C23H22Cl2N2O4 461.345000 |
XKUYNNZACAGYEX-LMSKBGPXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562819; PubChem:CID137355924
|
Local ready
Direct docking supported
|
|
E3L026779
BDB026779
|
US11407721, Example 67
CCC[C@H](c1nnn[nH]1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@@H]1c1ccc(Cl)cc1
|
C23H23Cl2N5O4 504.374000 |
AXLFRXXLVUJAFX-RMVXJAJNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562820; PubChem:CID118622847
|
Local ready
Direct docking supported
|
|
E3L026780
BDB026780
|
US11407721, Example 68
CCC[C@H](c1nnc(C)o1)N1C(=O)[C@@H](CC(=O)O)O[C@H](c2cccc(Cl)c2)[C@@H]1c1ccc(Cl)cc1
|
C25H25Cl2N3O5 518.397000 |
PPGOVTZCALBESV-YXPKMTABSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562821; PubChem:CID118622849
|
Local ready
Direct docking supported
|