| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L026741
BDB026741
|
US11407721, Example 27
CCC[C@H](C(=O)NS(C)(=O)=O)N1C(=O)[C@H](Cc2ccc(F)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H29Cl2FN2O5S 607.531000 |
UOSAUSMJYXDNQS-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562781; PubChem:CID86281780
|
Local ready
Direct docking supported
|
|
E3L026742
BDB026742
|
US11407721, Example 28
CCC[C@H](C(=O)N1CC(C(=O)O)C1)N1C(=O)[C@H](Cc2ccc(F)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C32H31Cl2FN2O5 613.513000 |
CAAWFBFPQTYVGS-AIQXTLEGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562782; PubChem:CID86281911
|
Local ready
Direct docking supported
|
|
E3L026743
BDB026743
|
US11407721, Example 29
CCC[C@H](C(=O)O)N1C(=O)[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)c(F)c2)[C@@H]1c1ccc(Cl)cc1
|
C28H25Cl2F2NO4 548.413000 |
JGSDUUHREWFLDE-FXSWLTOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562783; PubChem:CID86282047
|
Local ready
Direct docking supported
|
|
E3L026744
BDB026744
|
US11407721, Example 30
CCC[C@H](C(=O)O)N1C(=O)[C@@H](Cc2ccc(F)cc2)O[C@H](c2ccc(Cl)cc2C)[C@@H]1c1ccc(Cl)cc1
|
C29H28Cl2FNO4 544.450000 |
UVXJEGSLASNFDS-JVYGEBFASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562784; PubChem:CID86282051
|
Local ready
Direct docking supported
|
|
E3L026745
BDB026745
|
US11407721, Example 31
CCC[C@@H](CCC(=O)O)N1C(=O)[C@@H](Cc2ccc(F)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C30H30Cl2FNO4 558.477000 |
PTHOVXLFQNARAG-MFACLRLHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562785; PubChem:CID145748351
|
Local ready
Direct docking supported
|
|
E3L026746
BDB026746
|
US11407721, Example 32
CCC[C@H](C(=O)NCCCC(=O)O)N1C(=O)[C@H](Cc2ccc(C#N)cc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C33H33Cl2N3O5 622.549000 |
IOBJPQJJXSHZBT-HUAAZGBFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562786; PubChem:CID77108131
|
Local ready
Direct docking supported
|
|
E3L026747
BDB026747
|
US11407721, Example 34
CCC[C@@H](C(=O)NCC(N)=O)N1C(=O)[C@@H](Cc2ccc(C#N)cc2)O[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
|
C31H30Cl2N4O4 593.511000 |
UDWYSSZKWZKYFF-IXGYBEARSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562788; PubChem:CID118623018
|
Local ready
Direct docking supported
|
|
E3L026748
BDB026748
|
BDBM562789
CCC[C@H](c1nnn[nH]1)N1C(=O)[C@H](Cc2ccc(C#N)c(F)c2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H25Cl2FN6O2 579.463000 |
AYQYKRDXHPVENE-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562789; PubChem:CID86282188
|
Local ready
Direct docking supported
|
|
E3L026749
BDB026749
|
US11407721, Example 36
CCC[C@@H](c1nnn[nH]1)N1C(=O)[C@@H](Cc2ccc(I)cc2)O[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
|
C28H26Cl2IN5O2 662.359000 |
HCAYISRYXICNRK-ROXDYWFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562790; PubChem:CID86282329
|
Local ready
Direct docking supported
|
|
E3L026750
BDB026750
|
BDBM562791
CCC[C@H](C(=O)O)N1C(=O)CO[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C21H21Cl2NO4 422.308000 |
NHDJKSJILSOCFS-RLLQIKCJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562791; PubChem:CID86282330
|
Local ready
Direct docking supported
|
|
E3L026751
BDB026751
|
US11407721, Example 39
CN1C(=O)/C(=C/c2cccnc2)O[C@@H](c2ccccc2)[C@H]1c1ccc(Cl)cc1
|
C23H19ClN2O2 390.870000 |
HQLKDGGLZIBXPN-VBYAABMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562792; PubChem:CID118631957
|
Local ready
Direct docking supported
|
|
E3L026752
BDB026752
|
US11407721, Example 40
CN1C(=O)[C@@H](CCN2CCOCC2)O[C@H](c2ccc(Cl)cc2)[C@@H]1c1ccc(Cl)cc1
|
C23H26Cl2N2O3 449.378000 |
ISEMFQGMTRGCLK-BHIFYINESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562793; PubChem:CID86282331
|
Local ready
Direct docking supported
|
|
E3L026753
BDB026753
|
US11407721, Example 41
CN1C(=O)[C@H](Cc2ccncc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C23H20Cl2N2O2 427.331000 |
OGHYKDRSHULZRE-BDTNDASRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562794; PubChem:CID86282334
|
Local ready
Direct docking supported
|
|
E3L026754
BDB026754
|
US11407721, Example 42
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccncc2)O[C@@H](c2ccccc2)[C@H]1c1ccc(Cl)cc1
|
C27H27ClN2O4 478.976000 |
YZWHVSJCIRIEHU-RCTAOEEJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562795; PubChem:CID90371816
|
Local ready
Direct docking supported
|
|
E3L026755
BDB026755
|
US11407721, Example 43
CCC[C@H](C(=O)O)N1C(=O)CO[C@@H](c2ccc(Cl)cc2)[C@H]1c1cc2ccccc2[nH]1
|
C23H23ClN2O4 426.900000 |
HQRAQGJHPUFZPL-FCEUIQTBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562796; PubChem:CID86282465
|
Local ready
Direct docking supported
|
|
E3L026756
BDB026756
|
BDBM562797
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccccc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C28H27Cl2NO4 512.433000 |
SCIHNVZRVLKGMQ-ZJSPYRCASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562797; PubChem:CID86282738
|
Local ready
Direct docking supported
|
|
E3L026757
BDB026757
|
US11407721, Example 45
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccc(F)cc2C#N)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H25Cl2FN2O4 555.433000 |
LBKMRYPTFPFDCU-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562798; PubChem:CID86282603
|
Local ready
Direct docking supported
|
|
E3L026758
BDB026758
|
US11407721, Example 46
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccccc2C#N)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C29H26Cl2N2O4 537.443000 |
PWBYWLZBUHMMDL-RAVGUYNFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562799; PubChem:CID86282602
|
Local ready
Direct docking supported
|
|
E3L026759
BDB026759
|
US11407721, Example 47
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2ccccc2F)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C28H26Cl2FNO4 530.423000 |
AMKMOSMZFSCUOD-ZJSPYRCASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562800; PubChem:CID86282601
|
Local ready
Direct docking supported
|
|
E3L026760
BDB026760
|
US11407721, Example 48
CCC[C@H](C(=O)O)N1C(=O)[C@H](Cc2cccc(F)c2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C28H26Cl2FNO4 530.423000 |
WDHFWCFVVPABNM-ZJSPYRCASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM562801; PubChem:CID86282600
|
Local ready
Direct docking supported
|