| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027321
BDB027321
|
US11420970, Example 140
Cc1cc(C(F)F)ccc1-c1cc(Cn2cnc3c(N)ncnc32)c(N2CCC[C@](N)([C@H](O)C(F)F)C2)cn1
|
C26H28F4N8O 544.557000 |
LKOGIDSDIBCKAU-QFQXNSOFSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567939; PubChem:CID156073432
|
Local ready
Direct docking supported
|
|
E3L027322
BDB027322
|
US11420970, Example 141
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(C(F)(F)F)cc2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H24F6N8O 566.510000 |
OTZOFGDLBLPKLJ-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567940; PubChem:CID156073437
|
Local ready
Direct docking supported
|
|
E3L027323
BDB027323
|
US11420970, Example 142
Nc1ncnc2c1ncn2Cc1c(N2CCC[C@](N)([C@H](O)C(F)F)C2)cnc(-c2ccc(F)cc2F)c1F
|
C24H23F5N8O 534.493000 |
SKURVGSZEPSYCD-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567941; PubChem:CID156073453
|
Local ready
Direct docking supported
|
|
E3L027324
BDB027324
|
US11420970, Example 143
Cn1ncc2cc(-c3cc(Cn4cnc5c(N)ncnc54)c(N4CCC[C@](N)([C@H](O)C(F)F)C4)cn3)c(F)cc21
|
C26H27F3N10O 552.565000 |
YADRUOFMBRNEAR-ATIYNZHBSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567942; PubChem:CID156073456
|
Local ready
Direct docking supported
|
|
E3L027325
BDB027325
|
US11420970, Example 144
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(O)cc2F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H24F4N8O2 532.502000 |
OFESRDMDAGNRKY-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567943; PubChem:CID164850536
|
Local ready
Direct docking supported
|
|
E3L027326
BDB027326
|
US11420970, Example 145
Nc1ncnc2c1ncn2Cc1cc(C2CCCCC2)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H32F2N8O 486.571000 |
XJHAZWYYLFTDLT-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567944; PubChem:CID156073454
|
Local ready
Direct docking supported
|
|
E3L027327
BDB027327
|
US11420970, Example 146
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2C(F)F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H24F6N8O 566.510000 |
DBQTUCRUNGFEEL-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567945; PubChem:CID156073455
|
Local ready
Direct docking supported
|
|
E3L027328
BDB027328
|
US11420970, Example 147
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C24H24F4N8O 516.503000 |
UENCJGVXGSBJQG-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567946; PubChem:CID156073190
|
Local ready
Direct docking supported
|
|
E3L027329
BDB027329
|
US11420970, Example 148
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(Cl)cc2F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H24ClF3N8O 532.958000 |
QIHZOUNKSKTTRZ-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567947; PubChem:CID156073185
|
Local ready
Direct docking supported
|
|
E3L027330
BDB027330
|
US11420970, Example 149
COc1cc(F)c(-c2ncc(N3CCC[C@](N)([C@H](O)C(F)F)C3)c(Cn3cnc4c(N)ncnc43)c2F)cc1F
|
C25H25F5N8O2 564.519000 |
CDSARVHEGFZCCC-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567948; PubChem:CID156073183
|
Local ready
Direct docking supported
|
|
E3L027331
BDB027331
|
US11420970, Example 150
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(OC(F)F)cc2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H24F6N8O2 582.509000 |
OICNIWFEOUOBRQ-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567949; PubChem:CID156073181
|
Local ready
Direct docking supported
|
|
E3L027332
BDB027332
|
US11420970, Example 151
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H24F4N8O 516.503000 |
UENCJGVXGSBJQG-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567950; PubChem:CID156073187
|
Local ready
Direct docking supported
|
|
E3L027333
BDB027333
|
US11420970, Example 152
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(Cl)c(F)c2)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H24ClF3N8O 532.958000 |
SOQIUOAPFSBBMR-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567951; PubChem:CID156073261
|
Local ready
Direct docking supported
|
|
E3L027334
BDB027334
|
US11420970, Example 153
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(OC(F)F)cc2F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C25H25F5N8O2 564.519000 |
VXPKMDVRDJGJHP-CJFMBICVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567952; PubChem:CID156073255
|
Local ready
Direct docking supported
|
|
E3L027335
BDB027335
|
US11420970, Example 154
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)cc(C(F)F)c2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H24F6N8O 566.510000 |
PLIIMDOBLLHGNQ-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567953; PubChem:CID156073262
|
Local ready
Direct docking supported
|
|
E3L027336
BDB027336
|
US11420970, Example 155
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cn2)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C23H24F3N9O 499.501000 |
WUTTVSGGMUJTHP-WMZHIEFXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567954; PubChem:CID164850545
|
Local ready
Direct docking supported
|
|
E3L027337
BDB027337
|
US11420970, Example 156
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C24H23F5N8O 534.493000 |
RITHSQHPTNJAHO-GBXCKJPGSA-N | O96028, Q9BZ95 | Histone-lysine N-methyltransferase NSD2, Histone-lysine N-methyltransferase NSD3 |
BindingDB, PubChem
BindingDB:BDBM567955; PubChem:CID156069888
|
Local ready
Direct docking supported
|
|
E3L027338
BDB027338
|
US11420970, Example 157
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H23F5N8O 534.493000 |
RITHSQHPTNJAHO-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567956; PubChem:CID156069961
|
Local ready
Direct docking supported
|
|
E3L027339
BDB027339
|
US11420970, Example 158
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2C(F)F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H25F5N8O 548.520000 |
JJBKELQFVFMFOA-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567957; PubChem:CID156073180
|
Local ready
Direct docking supported
|
|
E3L027340
BDB027340
|
US11420970, Example 159
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2C(F)F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C25H25F5N8O 548.520000 |
JJBKELQFVFMFOA-CJFMBICVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567958; PubChem:CID156070268
|
Local ready
Direct docking supported
|