| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027361
BDB027361
|
US11420970, Example 180
Nc1ncnc2c1ncn2Cc1cc(-c2cnc(F)c(Cl)c2)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C26H23Cl2FN10 565.444000 |
WIUBHYIHNVSJJP-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567979; PubChem:CID156073156
|
Local ready
Direct docking supported
|
|
E3L027362
BDB027362
|
US11420970, Example 181
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4cccc(Cl)n4)C3)cn2)c(F)c1
|
C28H27ClFN9O 560.037000 |
HQHIGLBQTFOWMR-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567980; PubChem:CID156073161
|
Local ready
Direct docking supported
|
|
E3L027363
BDB027363
|
US11420970, Example 182
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(c2cccc(C3CC3)n2)C1
|
C30H30FN9 535.631000 |
LKVJFVQMMWWPTK-SSEXGKCCSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567981; PubChem:CID156073434
|
Local ready
Direct docking supported
|
|
E3L027364
BDB027364
|
US11420970, Example 183
C[C@H](F)c1cccc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)cc4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C29H29F2N9 541.610000 |
GMTBEJZBTBSSTB-RBSBEOHCSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567982; PubChem:CID156073433
|
Local ready
Direct docking supported
|
|
E3L027365
BDB027365
|
US11420970, Example 184
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(OC(F)F)cc2)ncc1N1CCCC(N)(c2cccc(Cl)n2)C1
|
C28H26ClF2N9O 578.027000 |
UWLKVXMIDOWWRG-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567983; PubChem:CID156073430
|
Local ready
Direct docking supported
|
|
E3L027366
BDB027366
|
US11420970, Example 185
Nc1ncnc2c1ncn2Cc1cc(-c2ccc3c(c2)CCO3)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C29H28ClN9O 554.058000 |
XHIOXHRRTGLAFK-GDLZYMKVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567984; PubChem:CID156073429
|
Local ready
Direct docking supported
|
|
E3L027367
BDB027367
|
US11420970, Example 186
Nc1ncnc2c1ncn2Cc1cc(-c2ccc3c(c2)OCO3)ncc1N1CCCC(N)(c2cccc(Cl)n2)C1
|
C28H26ClN9O2 556.030000 |
KPLOUGZCWQRDSX-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567985; PubChem:CID156073178
|
Local ready
Direct docking supported
|
|
E3L027368
BDB027368
|
US11420970, Example 187
COc1cc(F)c(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4cccc(Cl)n4)C3)cn2)cc1F
|
C28H26ClF2N9O 578.027000 |
NIRIZQAKWCLPPK-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567986; PubChem:CID156073176
|
Local ready
Direct docking supported
|
|
E3L027369
BDB027369
|
US11420970, Example 188
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4ccc(F)c(Cl)n4)C3)cn2)cc1F
|
C28H26ClF2N9O 578.027000 |
UPUOGLBNGLKLGX-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567987; PubChem:CID156073179
|
Local ready
Direct docking supported
|
|
E3L027370
BDB027370
|
US11420970, Example 189
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCCC(N)(c2ccc(F)cn2)C1
|
C27H25F2N9 513.556000 |
JTPBSHLLODCFCH-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567988; PubChem:CID156073175
|
Local ready
Direct docking supported
|
|
E3L027371
BDB027371
|
US11420970, Example 190
Cc1nc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)cc4)cc3Cn3cnc4c(N)ncnc43)C2)ccc1F
|
C28H27F2N9 527.583000 |
JGIQVKOGKUGKGV-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567989; PubChem:CID156073177
|
Local ready
Direct docking supported
|
|
E3L027372
BDB027372
|
US11420970, Example 191
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(Cl)n2)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C26H23Cl2FN10 565.444000 |
AQQVIOCUZPUTLC-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567990; PubChem:CID156073324
|
Local ready
Direct docking supported
|
|
E3L027373
BDB027373
|
US11420970, Example 192
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1C1CCC[C@](N)(c2nc(Cl)ccc2F)C1
|
C28H24ClF3N8 565.003000 |
USILTGLPCKMFRE-GMTYSHBUSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567991; PubChem:CID164850542
|
Local ready
Direct docking supported
|
|
E3L027374
BDB027374
|
US11420970, Example 193
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCCC(N)(c2ccc(F)c(CF)n2)C1
|
C28H26F3N9 545.573000 |
BPVWXGZDKBSDIB-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567992; PubChem:CID156073325
|
Local ready
Direct docking supported
|
|
E3L027375
BDB027375
|
US11420970, Example 194
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4cccc(Cl)n4)C3)cn2)nc1Cl
|
C27H26Cl2N10O 577.480000 |
UIHHKGMGGJQPCD-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567993; PubChem:CID156073323
|
Local ready
Direct docking supported
|
|
E3L027376
BDB027376
|
US11420970, Example 195
NC(=O)c1cccc(C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C28H26F2N10O 556.581000 |
UKHBICJBLWUTOV-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567994; PubChem:CID156073327
|
Local ready
Direct docking supported
|
|
E3L027377
BDB027377
|
US11420970, Example 196
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cn2)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C26H24ClFN10 530.999000 |
YRLVDPORXLXHRK-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567995; PubChem:CID156073192
|
Local ready
Direct docking supported
|
|
E3L027378
BDB027378
|
US11420970, Example 198
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2ccccn2)C1
|
C27H25F2N9 513.556000 |
FXAXMDGEXGUYBN-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567996; PubChem:CID156073186
|
Local ready
Direct docking supported
|
|
E3L027379
BDB027379
|
US11420970, Example 199
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2ncccc2F)C1
|
C27H24F3N9 531.546000 |
GKFLUWMYDXZNRX-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567997; PubChem:CID156073188
|
Local ready
Direct docking supported
|
|
E3L027380
BDB027380
|
US11420970, Example 200
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C27H24ClF2N9 548.001000 |
BRZJGOWPHWEFHB-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567998; PubChem:CID156073193
|
Local ready
Direct docking supported
|