| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027381
BDB027381
|
US11420970, Example 201
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2cccc(F)n2)C1
|
C27H24F3N9 531.546000 |
RRTHHQKNOGTJLZ-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567999; PubChem:CID164850517
|
Local ready
Direct docking supported
|
|
E3L027382
BDB027382
|
US11420970, Example 202
CCc1cccc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)cc4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C29H30FN9 523.620000 |
NCYXEBMLPISALN-GDLZYMKVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568000; PubChem:CID156073452
|
Local ready
Direct docking supported
|
|
E3L027383
BDB027383
|
US11420970, Example 203
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(c2cccc(C(F)F)n2)C1
|
C28H26F3N9 545.573000 |
YXLZXIYJGWTGJR-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568001; PubChem:CID156073451
|
Local ready
Direct docking supported
|
|
E3L027384
BDB027384
|
US11420970, Example 204
Nc1ncnc2c1ncn2Cc1cc(C2CC2)ncc1N1CCC[C@](N)(c2cccc(Cl)n2)C1
|
C24H26ClN9 475.988000 |
OJCOCPUCXXOTHC-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568002; PubChem:CID156073450
|
Local ready
Direct docking supported
|
|
E3L027385
BDB027385
|
US11420970, Example 205
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCCC(N)(c2cccc(Cl)n2)C1
|
C27H25ClFN9 530.011000 |
BUNQNXNFNAHDTA-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568003; PubChem:CID164850533
|
Local ready
Direct docking supported
|
|
E3L027386
BDB027386
|
US11420970, Example 206
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2cc(O)cc(F)n2)C1
|
C27H24F3N9O 547.545000 |
UUPSPCLZXQLYBQ-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568004; PubChem:CID156073150
|
Local ready
Direct docking supported
|
|
E3L027387
BDB027387
|
US11420970, Example 207
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4ccc(F)c(C)n4)C3)cn2)cc1F
|
C29H29F2N9O 557.609000 |
ITPBZSRQUYIHJE-GDLZYMKVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568005; PubChem:CID156073154
|
Local ready
Direct docking supported
|
|
E3L027388
BDB027388
|
US11420970, Example 208
N#Cc1cccc(C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C28H24F2N10 538.566000 |
MCZZITAOBLSPMM-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568006; PubChem:CID164850550
|
Local ready
Direct docking supported
|
|
E3L027389
BDB027389
|
US11420970, Example 209
N[C@]1(C2CCC(OC(F)F)CC2)CCCN(c2ccc(-c3ccc(F)c(F)c3)nc2)C1
|
C23H27F4N3O 437.481000 |
LPDPAYAUFRTNJY-OGRDWSCISA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568007; PubChem:CID164850500
|
Local ready
Direct docking supported
|
|
E3L027390
BDB027390
|
US11420970, Example 210
Nc1ncnc2c1ncn2Cc1cc(-c2ccc3nccn3c2)ncc1N1CCCC(N)(c2cccc(Cl)n2)C1
|
C28H26ClN11 552.046000 |
HOERZPAXLMNVBU-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568008; PubChem:CID156073153
|
Local ready
Direct docking supported
|
|
E3L027391
BDB027391
|
US11420970, Example 211
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4cccc(Cl)n4)C3)cn2)cc1
|
C28H28ClN9O 542.047000 |
NZFHRTPPWJECFN-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568009; PubChem:CID156073462
|
Local ready
Direct docking supported
|
|
E3L027392
BDB027392
|
US11420970, Example 212
C[C@@H](F)c1cccc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)cc4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C29H29F2N9 541.610000 |
GMTBEJZBTBSSTB-LDLUVENISA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568010; PubChem:CID156073463
|
Local ready
Direct docking supported
|
|
E3L027393
BDB027393
|
US11420970, Example 213
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4cccc(Cl)n4)C3)cn2)cc1F
|
C28H27ClFN9O 560.037000 |
LDDUFOGVERSWBB-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568011; PubChem:CID156073466
|
Local ready
Direct docking supported
|
|
E3L027394
BDB027394
|
US11420970, Example 214
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(c2ccc(O)c(F)n2)C1
|
C27H24F3N9O 547.545000 |
KRKLHQTWSPLDTB-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568012; PubChem:CID156073468
|
Local ready
Direct docking supported
|
|
E3L027395
BDB027395
|
US11420970, Example 215
CC(O)c1ccc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)nc1F
|
C29H28F3N9O 575.599000 |
MDQKXARHSMRMOT-DSANZHRBSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568013; PubChem:CID156073464
|
Local ready
Direct docking supported
|
|
E3L027396
BDB027396
|
US11420970, Example 216
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(c4ccc(F)c(Cl)n4)C3)cn2)cc1
|
C28H27ClFN9O 560.037000 |
RCDMOZVHTGIACA-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568014; PubChem:CID156073282
|
Local ready
Direct docking supported
|
|
E3L027397
BDB027397
|
US11420970, Example 217
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2cccc(O)n2)C1
|
C27H25F2N9O 529.555000 |
IYYMPTUOAWTMBR-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568015; PubChem:CID156073278
|
Local ready
Direct docking supported
|
|
E3L027398
BDB027398
|
US11420970, Example 218
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(c2ccc(F)c(C(F)F)n2)C1
|
C28H25F4N9 563.563000 |
NNHFVPNQISFHSW-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568016; PubChem:CID156073279
|
Local ready
Direct docking supported
|
|
E3L027399
BDB027399
|
US11420970, Example 219
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(c2cc(O)cc(Cl)n2)C1
|
C27H24ClF2N9O 564.000000 |
ZNWRIPLSMSPHMF-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568017; PubChem:CID156073283
|
Local ready
Direct docking supported
|
|
E3L027400
BDB027400
|
US11420970, Example 220
Cn1cnc2ccc(-c3cc(Cn4cnc5c(N)ncnc54)c(N4CCCC(N)(c5cccc(Cl)n5)C4)cn3)cc21
|
C29H28ClN11 566.073000 |
AXZIWLYZTNGOBI-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM568018; PubChem:CID156073284
|
Local ready
Direct docking supported
|