| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027341
BDB027341
|
US11420970, Example 160
COc1cc(F)c(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@@H](O)C(F)F)C3)cn2)cc1F
|
C25H26F4N8O2 546.529000 |
PIFXSVGCYBHXHR-SQJMNOBHSA-N | O96028, Q9BZ95 | Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567959; PubChem:CID156069377
|
Local ready
Direct docking supported
|
|
E3L027342
BDB027342
|
NSD2 inhibitor-1
COc1cc(F)c(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)cc1F
|
C25H26F4N8O2 546.529000 |
PIFXSVGCYBHXHR-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567960; PubChem:CID156069450
|
Local ready
Direct docking supported
|
|
E3L027343
BDB027343
|
US11420970, Example 162
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)c(C(F)F)c1
|
C26H28F4N8O2 560.556000 |
GDDLHAQSCGAKGC-QFQXNSOFSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567961; PubChem:CID156067092
|
Local ready
Direct docking supported
|
|
E3L027344
BDB027344
|
US11420970, Example 163
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@@H](O)C(F)F)C3)cn2)c(C(F)F)c1
|
C26H28F4N8O2 560.556000 |
GDDLHAQSCGAKGC-HFZDXXHNSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567962; PubChem:CID156073443
|
Local ready
Direct docking supported
|
|
E3L027345
BDB027345
|
US11420970, Example 164
COc1c(F)cc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)cc1F
|
C25H26F4N8O2 546.529000 |
QCLRHWIBLZTQTA-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567963; PubChem:CID156069968
|
Local ready
Direct docking supported
|
|
E3L027346
BDB027346
|
US11420970, Example 165
COc1c(F)cc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@@H](O)C(F)F)C3)cn2)cc1F
|
C25H26F4N8O2 546.529000 |
QCLRHWIBLZTQTA-SQJMNOBHSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567964; PubChem:CID156069923
|
Local ready
Direct docking supported
|
|
E3L027347
BDB027347
|
US11420970, Example 166
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@@H](O)C(F)F)C3)cn2)c(C(F)(F)F)c1
|
C26H27F5N8O2 578.546000 |
OIEVISJMZRPXHV-SQJMNOBHSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567965; PubChem:CID156069895
|
Local ready
Direct docking supported
|
|
E3L027348
BDB027348
|
US11420970, Example 167
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)c(C(F)(F)F)c1
|
C26H27F5N8O2 578.546000 |
OIEVISJMZRPXHV-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567966; PubChem:CID156069949
|
Local ready
Direct docking supported
|
|
E3L027349
BDB027349
|
US11420970, Example 168
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@H](O)C(F)F)C3)cn2)c(Cl)c1
|
C25H27ClF2N8O2 544.994000 |
DSZJEJFEQPHGOS-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567967; PubChem:CID156069901
|
Local ready
Direct docking supported
|
|
E3L027350
BDB027350
|
US11420970, Example 169
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)([C@@H](O)C(F)F)C3)cn2)c(Cl)c1
|
C25H27ClF2N8O2 544.994000 |
DSZJEJFEQPHGOS-SQJMNOBHSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567968; PubChem:CID156069754
|
Local ready
Direct docking supported
|
|
E3L027351
BDB027351
|
US11420970, Example 170
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2C(F)F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H24F6N8O 566.510000 |
CEIVZPPHKBDONO-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567969; PubChem:CID156069860
|
Local ready
Direct docking supported
|
|
E3L027352
BDB027352
|
US11420970, Example 171
Nc1ncnc2c1ncn2Cc1cc(-c2cc(F)c(F)cc2C(F)F)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C25H24F6N8O 566.510000 |
CEIVZPPHKBDONO-CJFMBICVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567970; PubChem:CID156070074
|
Local ready
Direct docking supported
|
|
E3L027353
BDB027353
|
US11420970, Example 172
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2F)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C24H23F5N8O 534.493000 |
GDXCBZJBGSNOOL-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567971; PubChem:CID156069862
|
Local ready
Direct docking supported
|
|
E3L027354
BDB027354
|
US11420970, Example 173
COc1cc(F)ccc1-c1cc(Cn2cnc3c(N)ncnc32)c(N2CCC[C@](N)([C@H](O)C(F)F)C2)cn1
|
C25H27F3N8O2 528.539000 |
JJEPJVZPBAPWBK-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567972; PubChem:CID156070077
|
Local ready
Direct docking supported
|
|
E3L027355
BDB027355
|
US11420970, Example 174
COc1cc(F)ccc1-c1cc(Cn2cnc3c(N)ncnc32)c(N2CCC[C@](N)([C@@H](O)C(F)F)C2)cn1
|
C25H27F3N8O2 528.539000 |
JJEPJVZPBAPWBK-SQJMNOBHSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567973; PubChem:CID156073349
|
Local ready
Direct docking supported
|
|
E3L027356
BDB027356
|
US11420970, Example 175
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(Cl)n2)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C23H23ClF3N9O 533.946000 |
MFNSLFHVLUFBDA-WZONZLPQSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567974; PubChem:CID156070001
|
Local ready
Direct docking supported
|
|
E3L027357
BDB027357
|
US11420970, Example 176
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(Cl)n2)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C23H23ClF3N9O 533.946000 |
MFNSLFHVLUFBDA-FDDCHVKYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567975; PubChem:CID156069866
|
Local ready
Direct docking supported
|
|
E3L027358
BDB027358
|
US11420970, Example 177
COC(=O)NC1(c2cccc(C)n2)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ncnc32)C1
|
C40H45F2N9O6 785.853000 |
FHGOSDAYQXVDBZ-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567976; PubChem:CID156637867
|
Local ready
Direct docking supported
|
|
E3L027359
BDB027359
|
US11420970, Example 178
COc1cccc([C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C28H27F2N9O 543.582000 |
DZVYFRAEMHXCTH-MUUNZHRXSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567977; PubChem:CID156073160
|
Local ready
Direct docking supported
|
|
E3L027360
BDB027360
|
US11420970, Example 179
Nc1ncnc2c1ncn2Cc1cc(-c2ccc3c(c2)COC3)ncc1N1CCCC(N)(c2cccc(Cl)n2)C1
|
C29H28ClN9O 554.058000 |
VHZHCEQPVWYGDJ-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567978; PubChem:CID156073158
|
Local ready
Direct docking supported
|