| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L034181
BDB034181
|
US20240246935, Example 35
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5cccc(OC(F)(F)F)c5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
VUHDLHBVLCWRGI-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686456; PubChem:CID166469115
|
Local ready
Direct docking supported
|
|
E3L034182
BDB034182
|
US20240246935, Example 36
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5OC(F)(F)F)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
BJKUCJPQXSYBIW-MFXHTCIWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686457; PubChem:CID166468843
|
Local ready
Direct docking supported
|
|
E3L034183
BDB034183
|
US20240246935, Example 37
N#Cc1cc(Cl)ccc1C1CN([C@@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29ClN4O4 533.028000 |
KOLPLYWGRIIREE-ITNFAHLUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686458; PubChem:CID166469232
|
Local ready
Direct docking supported
|
|
E3L034184
BDB034184
|
US20240246935, Example 38
N#Cc1cc(Cl)ccc1C1CN([C@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29ClN4O4 533.028000 |
KOLPLYWGRIIREE-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686459; PubChem:CID166468877
|
Local ready
Direct docking supported
|
|
E3L034185
BDB034185
|
US20240246935, Example 40
N#Cc1cc(Cl)ccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29ClN4O4 533.028000 |
KOLPLYWGRIIREE-KCIKGWAESA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686461; PubChem:CID166468895
|
Local ready
Direct docking supported
|
|
E3L034186
BDB034186
|
US20240246935, Example 41
O=C1CCC(N2Cc3c(ccc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5)C4)c3Cl)C2=O)C(=O)N1
|
C28H30ClN3O4 508.018000 |
SAIAQJVYFFZYQU-LIMDNCRJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686462; PubChem:CID166468899
|
Local ready
Direct docking supported
|
|
E3L034187
BDB034187
|
US20240246935, Example 43
N#Cc1cc(F)ccc1C1CN([C@@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29FN4O4 516.573000 |
IXURQSOFGHUSSF-NCKFGJJNSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686464; PubChem:CID167306997
|
Local ready
Direct docking supported
|
|
E3L034188
BDB034188
|
US20240246935, Example 44
N#Cc1cc(F)ccc1C1CN([C@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29FN4O4 516.573000 |
IXURQSOFGHUSSF-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686465; PubChem:CID166469194
|
Local ready
Direct docking supported
|
|
E3L034189
BDB034189
|
US20240246935, Example 46
N#Cc1cc(F)ccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H29FN4O4 516.573000 |
IXURQSOFGHUSSF-KCIKGWAESA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686467; PubChem:CID166469072
|
Local ready
Direct docking supported
|
|
E3L034190
BDB034190
|
US20240246935, Example 47
N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c(Cl)c1
|
C29H29ClN4O4 533.028000 |
VVAWSIVQULOUDG-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686468; PubChem:CID166468896
|
Local ready
Direct docking supported
|
|
E3L034191
BDB034191
|
US20240246935, Example 49
N#Cc1ccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c(Cl)c1
|
C29H29ClN4O4 533.028000 |
VVAWSIVQULOUDG-KCIKGWAESA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686470; PubChem:CID166469042
|
Local ready
Direct docking supported
|
|
E3L034192
BDB034192
|
US20240246935, Example 50
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(F)cc5)C4)ccc3C2=O)C(=O)N1
|
C28H30FN3O4 491.563000 |
DVMNBFKJAKDJAH-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686471; PubChem:CID166468871
|
Local ready
Direct docking supported
|
|
E3L034193
BDB034193
|
US20240246935, Example 52
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5)C4)c(F)cc3C2=O)C(=O)N1
|
C28H30FN3O4 491.563000 |
KLPMNQMEMDNPFV-OTKIHZFJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686473; PubChem:CID166469150
|
Local ready
Direct docking supported
|
|
E3L034194
BDB034194
|
US20240246935, Example 54
O=C1CCC(N2Cc3cc(O[C@@H]4CCCC[C@H]4N4CCC4c4ccccc4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
KODSUWFQBIOQCO-RULIFZQXSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686475; PubChem:CID167306946
|
Local ready
Direct docking supported
|
|
E3L034195
BDB034195
|
US20240246935, Example 55
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CCC4c4ccccc4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
KODSUWFQBIOQCO-CZKABKHRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686476; PubChem:CID166469120
|
Local ready
Direct docking supported
|
|
E3L034196
BDB034196
|
US20240246935, Example 56
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@H]4N4CCC4c4ccccc4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
KODSUWFQBIOQCO-DZIFKCOOSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686477; PubChem:CID166468892
|
Local ready
Direct docking supported
|
|
E3L034197
BDB034197
|
US20240246935, Example 57
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(F)cc5F)C4)ccc3C2=O)C(=O)N1
|
C28H29F2N3O4 509.553000 |
XVGVCDNDEKXDOT-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686478; PubChem:CID166469186
|
Local ready
Direct docking supported
|
|
E3L034198
BDB034198
|
US20240246935, Example 58
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(C(F)(F)F)cc5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O4 541.570000 |
BHUZYUQKILIAIW-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686479; PubChem:CID166469243
|
Local ready
Direct docking supported
|
|
E3L034199
BDB034199
|
US20240246935, Example 59
O=C1CCC(N2Cc3cc(O[C@@H]4CCCC[C@@H]4N4CC(c5ccc(C(F)(F)F)cc5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O4 541.570000 |
BHUZYUQKILIAIW-QNRWSGHRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686480; PubChem:CID166468854
|
Local ready
Direct docking supported
|
|
E3L034200
BDB034200
|
US20240246935, Example 60
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(OC(F)(F)F)cc5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
KACCHMVEEUHVIP-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686481; PubChem:CID166469045
|
Local ready
Direct docking supported
|