| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L034221
BDB034221
|
US20240246935, Example 84
N#Cc1cc(Cl)ccc1C1CN([C@H]2CCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C28H27ClN4O4 519.001000 |
OXAOBLMMSKVSTA-QNRWSGHRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686505; PubChem:CID169030281
|
Local ready
Direct docking supported
|
|
E3L034222
BDB034222
|
US20240246935, Example 85
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCCC[C@@H]5N5CC(c6ccc(F)cc6Cl)C5)ccc4C3=O)CC1C2
|
C29H29ClFN3O4 538.019000 |
ZOHPDTMOHJGCRX-QGCWWAPOSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686506; PubChem:CID166469242
|
Local ready
Direct docking supported
|
|
E3L034223
BDB034223
|
US20240246935, Example 86
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CC(c6ccc(F)cc6Cl)C5)ccc4C3=O)CC1C2
|
C28H27ClFN3O4 523.992000 |
HPNNYDLLFGBDLQ-QAMMTEFWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686507; PubChem:CID166469208
|
Local ready
Direct docking supported
|
|
E3L034224
BDB034224
|
US20240246935, Example 87
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CC(c6cccc(F)c6)C5)ccc4C3=O)CC1C2
|
C28H28FN3O4 489.547000 |
VYZZCJGEWQSQBG-GGTKOGOXSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686508; PubChem:CID166469225
|
Local ready
Direct docking supported
|
|
E3L034225
BDB034225
|
US20240246935, Example 88
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CC(c5cccc(F)c5)C4)ccc3C2=O)C(=O)N1
|
C27H28FN3O4 477.536000 |
VFXCATJGAJYURP-OTKIHZFJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686509; PubChem:CID166469177
|
Local ready
Direct docking supported
|
|
E3L034226
BDB034226
|
US20240246935, Example 89
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCCC[C@@H]5N5CC(c6cccc(F)c6)C5)ccc4C3=O)CC1C2
|
C29H30FN3O4 503.574000 |
ZEQMCSZYRVXYQW-UQKARQJCSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686510; PubChem:CID166468901
|
Local ready
Direct docking supported
|
|
E3L034227
BDB034227
|
US20240246935, Example 90
N#Cc1ccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c(F)c1
|
C30H29FN4O4 528.584000 |
WGMQQYCYSPXKPN-QSMSFNOWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686511; PubChem:CID166469140
|
Local ready
Direct docking supported
|
|
E3L034228
BDB034228
|
US20240246935, Example 91
N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c(F)c1
|
C30H29FN4O4 528.584000 |
WGMQQYCYSPXKPN-CHZILUMDSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686512; PubChem:CID166469253
|
Local ready
Direct docking supported
|
|
E3L034229
BDB034229
|
US20240246935, Example 92
N#Cc1ccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)cc1
|
C30H30N4O4 510.594000 |
QELICZDPXLIBGQ-URGSMFQNSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686513; PubChem:CID167306956
|
Local ready
Direct docking supported
|
|
E3L034230
BDB034230
|
US20240246935, Example 93
N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)cc1
|
C30H30N4O4 510.594000 |
QELICZDPXLIBGQ-KUJIZVNSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686514; PubChem:CID166469070
|
Local ready
Direct docking supported
|
|
E3L034231
BDB034231
|
US20240246935, Example 94
N#Cc1ccccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1
|
C30H30N4O4 510.594000 |
SLXLIDSVARTODS-AKXSHQFSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686515; PubChem:CID166469056
|
Local ready
Direct docking supported
|
|
E3L034232
BDB034232
|
US20240246935, Example 95
N#Cc1ccccc1C1CN([C@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1
|
C30H30N4O4 510.594000 |
SLXLIDSVARTODS-JFHSDLNVSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686516; PubChem:CID166468863
|
Local ready
Direct docking supported
|
|
E3L034233
BDB034233
|
US20240246935, Example 96
CC1(c2ccccc2)CN([C@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H33N3O4 487.600000 |
NECVJOWEYYAELX-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686517; PubChem:CID169030274
|
Local ready
Direct docking supported
|
|
E3L034234
BDB034234
|
US20240246935, Example 97
CC1(c2ccccc2)CN([C@@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H33N3O4 487.600000 |
NECVJOWEYYAELX-PPCJQXESSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686518; PubChem:CID169030303
|
Local ready
Direct docking supported
|
|
E3L034235
BDB034235
|
US20240246935, Example 98
N#Cc1ccc(C2CN(C3CCCC3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1
|
C28H28N4O4 484.556000 |
WZHDLMDPIYZYGB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686519; PubChem:CID166469029
|
Local ready
Direct docking supported
|
|
E3L034236
BDB034236
|
US20240246935, Example 103
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(F)cc5Cl)C4)ccc3C2=O)C(=O)N1
|
C28H29ClFN3O4 526.008000 |
BLQUOOUXDNIYNP-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686524; PubChem:CID166469106
|
Local ready
Direct docking supported
|
|
E3L034237
BDB034237
|
US20240246935, Example 104
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CC(c5ccc(F)cc5Cl)C4)ccc3C2=O)C(=O)N1
|
C27H27ClFN3O4 511.981000 |
PONDLXPPMGYPKU-OTKIHZFJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686525; PubChem:CID166469099
|
Local ready
Direct docking supported
|
|
E3L034238
BDB034238
|
US20240246935, Example 105
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CC(c6ccccc6)C5)ccc4C3=O)CC1C2
|
C28H29N3O4 471.557000 |
YDPHRJUTDBUMTN-NLCPVOBASA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686526; PubChem:CID166468820
|
Local ready
Direct docking supported
|
|
E3L034239
BDB034239
|
US20240246935, Example 106
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCCC[C@@H]5N5CCC(c6ccccc6)C5)ccc4C3=O)CC1C2
|
C30H33N3O4 499.611000 |
FBAFSJDBUPKOQD-IBBJLJOPSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686527; PubChem:CID166468797
|
Local ready
Direct docking supported
|
|
E3L034240
BDB034240
|
US20240246935, Example 107
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CCC(c6ccccc6)C5)ccc4C3=O)CC1C2
|
C29H31N3O4 485.584000 |
HPPDCGYHJNLKTQ-IRCHEXTCSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686528; PubChem:CID167306859
|
Local ready
Direct docking supported
|