| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L034201
BDB034201
|
US20240246935, Example 61
O=C1CCC(N2Cc3cc(O[C@@H]4CCCC[C@@H]4N4CC(c5ccc(OC(F)(F)F)cc5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
KACCHMVEEUHVIP-QNRWSGHRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686482; PubChem:CID167306910
|
Local ready
Direct docking supported
|
|
E3L034202
BDB034202
|
US20240246935, Example 63
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@H]4N4CC(c5ccc(OC(F)(F)F)cc5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
KACCHMVEEUHVIP-PPCJQXESSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686484; PubChem:CID166468756
|
Local ready
Direct docking supported
|
|
E3L034203
BDB034203
|
US20240246935, Example 64
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5cccc(F)c5F)C4)ccc3C2=O)C(=O)N1
|
C28H29F2N3O4 509.553000 |
SOUPBOVQNGQLQM-OTKIHZFJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686485; PubChem:CID166469091
|
Local ready
Direct docking supported
|
|
E3L034204
BDB034204
|
US20240246935, Example 65
O=C1CCC(N2Cc3c(ccc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5)C4)c3F)C2=O)C(=O)N1
|
C28H30FN3O4 491.563000 |
RIQVFCDNSXZUJO-LIMDNCRJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686486; PubChem:CID166469001
|
Local ready
Direct docking supported
|
|
E3L034205
BDB034205
|
US20240246935, Example 67
O=C1CCC(N2Cc3cc(OC4CCCCC4N4CC(c5cccc(OC(F)(F)F)c5)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
VUHDLHBVLCWRGI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686488; PubChem:CID166469172
|
Local ready
Direct docking supported
|
|
E3L034206
BDB034206
|
US20240246935, Example 68
O=C1CCC(N2Cc3cc(OC4CCCCC4N4CC(c5ccccc5OC(F)(F)F)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
BJKUCJPQXSYBIW-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686489; PubChem:CID166469119
|
Local ready
Direct docking supported
|
|
E3L034207
BDB034207
|
US20240246935, Example 69
O=C1CCC(N2Cc3cc(OC4CCCCC4N4CC(c5ccccc5C(F)(F)F)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O4 541.570000 |
ADTJOHKRUYWZNE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686490; PubChem:CID166468925
|
Local ready
Direct docking supported
|
|
E3L034208
BDB034208
|
US20240246935, Example 70
N#Cc1cc(F)ccc1C1CN([C@@H]2CCC[C@@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1
|
C29H27FN4O4 514.557000 |
WAQJMVNBJATBFL-DNZVTAPUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686491; PubChem:CID166468972
|
Local ready
Direct docking supported
|
|
E3L034209
BDB034209
|
US20240246935, Example 71
N#Cc1cc(F)ccc1C1CN([C@@H]2CCC[C@H]2Oc2ccc3c(c2)CN(C24CC(C2)C(=O)NC4=O)C3=O)C1
|
C29H27FN4O4 514.557000 |
WAQJMVNBJATBFL-PJOZHDSTSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686492; PubChem:CID166469197
|
Local ready
Direct docking supported
|
|
E3L034210
BDB034210
|
US20240246935, Example 72
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CCC(c5ccccc5)CC4)ccc3C2=O)C(=O)N1
|
C29H33N3O4 487.600000 |
IOKRISVPYBIDNL-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686493; PubChem:CID166469181
|
Local ready
Direct docking supported
|
|
E3L034211
BDB034211
|
US20240246935, Example 73
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CC(c5ccc(-n6cccn6)cc5)C4)ccc3C2=O)C(=O)N1
|
C30H31N5O4 525.609000 |
CDFJOOSXMYKVQQ-LLOGBAKRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686494; PubChem:CID166468791
|
Local ready
Direct docking supported
|
|
E3L034212
BDB034212
|
US20240246935, Example 75
N#Cc1ccc(C2CN([C@@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c(Cl)c1
|
C29H29ClN4O4 533.028000 |
VVAWSIVQULOUDG-ITNFAHLUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686496; PubChem:CID166469224
|
Local ready
Direct docking supported
|
|
E3L034213
BDB034213
|
US20240246935, Example 76
N#Cc1cccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c1
|
C29H30N4O4 498.583000 |
FCFHFBKDFKYODE-KCIKGWAESA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686497; PubChem:CID166469235
|
Local ready
Direct docking supported
|
|
E3L034214
BDB034214
|
US20240246935, Example 77
N#Cc1cccc(C2CN([C@H]3CCCC[C@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c1
|
C30H30N4O4 510.594000 |
VDGISIMRXHLHBN-URGSMFQNSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686498; PubChem:CID166469116
|
Local ready
Direct docking supported
|
|
E3L034215
BDB034215
|
US20240246935, Example 78
N#Cc1cccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C35CC(C3)C(=O)NC5=O)C4=O)C2)c1
|
C30H30N4O4 510.594000 |
VDGISIMRXHLHBN-KUJIZVNSSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686499; PubChem:CID166469234
|
Local ready
Direct docking supported
|
|
E3L034216
BDB034216
|
US20240246935, Example 79
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CCC(c5ccccc5)CC4)ccc3C2=O)C(=O)N1
|
C30H35N3O4 501.627000 |
XHCDFDXBDMNSNN-LLOGBAKRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686500; PubChem:CID166469230
|
Local ready
Direct docking supported
|
|
E3L034217
BDB034217
|
US20240246935, Example 80
O=C1CCC(N2Cc3c(ccc(O[C@H]4CCCC[C@@H]4N4CC(c5cccc(OC(F)F)c5)C4)c3F)C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
DJAKGNXHXRLVEK-LIMDNCRJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686501; PubChem:CID169030298
|
Local ready
Direct docking supported
|
|
E3L034218
BDB034218
|
US20240246935, Example 81
O=C1CCC(N2Cc3c(ccc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(OC(F)F)cc5)C4)c3F)C2=O)C(=O)N1
|
C29H30F3N3O5 557.569000 |
WRKMEHIMOXPCSL-LIMDNCRJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686502; PubChem:CID169030286
|
Local ready
Direct docking supported
|
|
E3L034219
BDB034219
|
US20240246935, Example 82
O=C1NC(=O)C2(N3Cc4cc(O[C@H]5CCC[C@@H]5N5CC(c6ccccc6Cl)C5)ccc4C3=O)CC1C2
|
C28H28ClN3O4 506.002000 |
FMWPHIIDMRKFRP-VPBDZVEJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686503; PubChem:CID167306891
|
Local ready
Direct docking supported
|
|
E3L034220
BDB034220
|
US20240246935, Example 83
N#Cc1cc(Cl)ccc1C1CN([C@H]2CCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C28H27ClN4O4 519.001000 |
OXAOBLMMSKVSTA-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686504; PubChem:CID169030295
|
Local ready
Direct docking supported
|