| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L034241
BDB034241
|
US20240246935, Example 108
N#Cc1ccccc1C1CN([C@H]2CCCC[C@@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H30N4O4 498.583000 |
QMPPHBLEILQRPD-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686529; PubChem:CID166469066
|
Local ready
Direct docking supported
|
|
E3L034242
BDB034242
|
US20240246935, Example 109
N#Cc1ccccc1C1CN([C@H]2CCCC[C@H]2Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C29H30N4O4 498.583000 |
QMPPHBLEILQRPD-KCIKGWAESA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686530; PubChem:CID166468950
|
Local ready
Direct docking supported
|
|
E3L034243
BDB034243
|
US20240246935, Example 110
N#Cc1ccc(C2CN(C3CCCC3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1F
|
C28H27FN4O4 502.546000 |
MJGIDMWRHLMUFQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686531; PubChem:CID166468812
|
Local ready
Direct docking supported
|
|
E3L034244
BDB034244
|
US20240246935, Example 111
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5cccc(F)c5)C4)ccc3C2=O)C(=O)N1
|
C28H30FN3O4 491.563000 |
YGNCHKSHVAJENZ-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686532; PubChem:CID166468796
|
Local ready
Direct docking supported
|
|
E3L034245
BDB034245
|
US20240246935, Example 112
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5cccc(N6CCOCC6)c5)C4)ccc3C2=O)C(=O)N1
|
C32H38N4O5 558.679000 |
QUAKGNVZJKIZKT-QBGWAWDMSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686533; PubChem:CID166469024
|
Local ready
Direct docking supported
|
|
E3L034246
BDB034246
|
US20240246935, Example 113
N#Cc1cccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c1
|
C29H30N4O4 498.583000 |
FCFHFBKDFKYODE-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686534; PubChem:CID166469037
|
Local ready
Direct docking supported
|
|
E3L034247
BDB034247
|
US20240246935, Example 115
N#Cc1ccc(C2CN([C@@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c(F)c1
|
C29H29FN4O4 516.573000 |
ATIBZKFTCXCIGR-ITNFAHLUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686535; PubChem:CID166469074
|
Local ready
Direct docking supported
|
|
E3L034248
BDB034248
|
US20240246935, Example 116
N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c(F)c1
|
C29H29FN4O4 516.573000 |
ATIBZKFTCXCIGR-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686536; PubChem:CID166468813
|
Local ready
Direct docking supported
|
|
E3L034249
BDB034249
|
US20240246935, Example 117
N#Cc1ccc(C2CN(C3CCCCC3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1
|
C29H30N4O4 498.583000 |
OSZGWRSNWWMTPS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686537; PubChem:CID166469035
|
Local ready
Direct docking supported
|
|
E3L034250
BDB034250
|
US20240246935, Example 118
O=C1CCC(N2Cc3cc(OC4CCCCC4N4CC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
DQYZQRGRHXEYPT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686538; PubChem:CID166469211
|
Local ready
Direct docking supported
|
|
E3L034251
BDB034251
|
US20240246935, Example 119
N#Cc1ccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1F
|
C29H29FN4O4 516.573000 |
NDZBHWLWXPFZRQ-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686539; PubChem:CID166469009
|
Local ready
Direct docking supported
|
|
E3L034252
BDB034252
|
US20240246935, Example 120
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C27H29N3O4 459.546000 |
OVYTZHPBZLSZRR-OTKIHZFJSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686540; PubChem:CID166468801
|
Local ready
Direct docking supported
|
|
E3L034253
BDB034253
|
US20240246935, Example 121
O=C1CCC(N2Cc3cc(O[C@H]4CCC[C@@H]4N4CCC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
QJMSCZYLMFUEHU-AXOKTRKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686541; PubChem:CID166469138
|
Local ready
Direct docking supported
|
|
E3L034254
BDB034254
|
US20240246935, Example 122
N#Cc1ccc(C2CN([C@@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)cc1F
|
C29H29FN4O4 516.573000 |
NDZBHWLWXPFZRQ-ITNFAHLUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686542; PubChem:CID166469108
|
Local ready
Direct docking supported
|
|
E3L034255
BDB034255
|
US20240246935, Example 124
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccc(N6CCOCC6)cc5)C4)ccc3C2=O)C(=O)N1
|
C32H38N4O5 558.679000 |
XVXVSENSXBWMNM-QBGWAWDMSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686544; PubChem:CID166468772
|
Local ready
Direct docking supported
|
|
E3L034256
BDB034256
|
US20240246935, Example 125
O=C1CC[C@@H](N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
DQYZQRGRHXEYPT-GVAUOCQISA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686545; PubChem:CID166468849
|
Local ready
Direct docking supported
|
|
E3L034257
BDB034257
|
US20240246935, Example 126
COc1cccc(C2CN([C@H]3CCCC[C@@H]3Oc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)C2)c1
|
C29H33N3O5 503.599000 |
UWHATYRSJFKQFU-ZURQMKNRSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686546; PubChem:CID166468885
|
Local ready
Direct docking supported
|
|
E3L034258
BDB034258
|
(S,S)-Plx-4545
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
DQYZQRGRHXEYPT-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686547; PubChem:CID166468781
|
Local ready
Direct docking supported
|
|
E3L034259
BDB034259
|
US20240246935, Example 128
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@H]4N4CC(c5ccccc5)C4)ccc3C2=O)C(=O)N1
|
C28H31N3O4 473.573000 |
DQYZQRGRHXEYPT-PPCJQXESSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686548; PubChem:CID166469222
|
Local ready
Direct docking supported
|
|
E3L034260
BDB034260
|
US20240246935, Example 129
O=C1CCC(N2Cc3cc(O[C@H]4CCCC[C@@H]4N4CC(c5ccccc5C(F)(F)F)C4)ccc3C2=O)C(=O)N1
|
C29H30F3N3O4 541.570000 |
ADTJOHKRUYWZNE-PFIFLBKHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM686549; PubChem:CID166469226
|
Local ready
Direct docking supported
|