| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035021
BDB035021
|
US20240368153, Example 14-2
CC(=O)N(Cc1cc2nc(N)c(C)cc2[nH]1)c1ccc2ccccc2c1C#N
|
C22H19N5O 369.428000 |
SRFXFLSPHHYVFE-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703948; PubChem:CID166460472
|
Local ready
Direct docking supported
|
|
E3L035022
BDB035022
|
US20240368153, Example 14-3
CC(=O)NCc1cc2nc(N)c(C)cc2[nH]1
|
C11H14N4O 218.260000 |
RGXQSWHBKILFMU-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703949; PubChem:CID166460525
|
Local ready
Direct docking supported
|
|
E3L035023
BDB035023
|
US20240368153, Example 14-4
CC(=O)N(C)Cc1cc2nc(N)c(C)cc2[nH]1
|
C12H16N4O 232.287000 |
DRNMZEZHPOWYGC-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703950; PubChem:CID166460421
|
Local ready
Direct docking supported
|
|
E3L035024
BDB035024
|
US20240368153, Example 14-5
Cc1cc2[nH]c(C(C#N)N3C(=O)c4ccccc4C3=O)cc2nc1N
|
C18H13N5O2 331.335000 |
VVGLLHBPUULIFD-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703951; PubChem:CID166460424
|
Local ready
Direct docking supported
|
|
E3L035025
BDB035025
|
US20240368153, Example 14-6
Cc1cc2[nH]c(CN3CCc4ccccc4C3=O)cc2nc1N
|
C18H18N4O 306.369000 |
CJVPMAFUDRCSAN-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703952; PubChem:CID166460492
|
Local ready
Direct docking supported
|
|
E3L035026
BDB035026
|
US20240368153, Example 14-7
Cc1cc2[nH]c(Cn3ccc4ccccc4c3=O)cc2nc1N
|
C18H16N4O 304.353000 |
LLIVSJBAWSHGHR-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703953; PubChem:CID166460405
|
Local ready
Direct docking supported
|
|
E3L035027
BDB035027
|
US20240368153, Example 15-1
Cc1cc2c(cc(CNC(=O)c3ccccc3)n2C2CC2)nc1N
|
C19H20N4O 320.396000 |
VISXTHYKJVPMPV-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703954; PubChem:CID166460552
|
Local ready
Direct docking supported
|
|
E3L035028
BDB035028
|
US20240368153, Example 15-2
CC(=O)N1CCC(=O)n2c(cc3nc(N)c(C)cc32)C1
|
C14H16N4O2 272.308000 |
ZTGBRNOPPKWPHC-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703955; PubChem:CID172487101
|
Local ready
Direct docking supported
|
|
E3L035029
BDB035029
|
US20240368153, Example 15-3
Cc1cc2c(cc(CNC(=O)c3ccccc3)n2C)nc1N
|
C17H18N4O 294.358000 |
VMKVCMLJEAZPBI-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703956; PubChem:CID172487065
|
Local ready
Direct docking supported
|
|
E3L035030
BDB035030
|
US20240368153, Example 15-4
C#Cc1c(CNC(=O)c2ccccc2)[nH]c2cc(C)c(N)nc12
|
C18H16N4O 304.353000 |
XPQABPZCZXQLOB-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703957; PubChem:CID166460467
|
Local ready
Direct docking supported
|
|
E3L035031
BDB035031
|
US20240368153, Example 15-5
CC(=O)c1c(CNC(=O)c2ccccc2)[nH]c2cc(C)c(N)nc12
|
C18H18N4O2 322.368000 |
CJPBVLSJNVWBJW-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703958; PubChem:CID166460479
|
Local ready
Direct docking supported
|
|
E3L035032
BDB035032
|
US20240368153, Example 15-6
Cc1cc2[nH]c(CNC(=O)c3ccccc3)c(C#N)c2nc1N
|
C17H15N5O 305.341000 |
QUVGHZVWWAPAJQ-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703959; PubChem:CID166460522
|
Local ready
Direct docking supported
|
|
E3L035033
BDB035033
|
BDBM703960
CC(=O)NCc1cc2nc(N)c(C)cc2n1C(C)=O
|
C13H16N4O2 260.297000 |
ZOYLZGNVMGRXLX-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703960; PubChem:CID166460487
|
Local ready
Direct docking supported
|
|
E3L035034
BDB035034
|
US20240368153, Example 15-8
CC(=O)N(C)Cc1cc2nc(N)c(C)cc2n1C(C)=O
|
C14H18N4O2 274.324000 |
ABXMLWXQJFJWIU-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703961; PubChem:CID166460458
|
Local ready
Direct docking supported
|
|
E3L035035
BDB035035
|
US20240368153, Example 16-1
Cc1cc2sc(CNC(=O)c3ccccc3)cc2nc1N
|
C16H15N3OS 297.383000 |
FUBWQWVGELGMLQ-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703962; PubChem:CID166460526
|
Local ready
Direct docking supported
|
|
E3L035036
BDB035036
|
US20240368153, Example 10-1
Cc1cc2[nH]c(C(=O)N(Cc3ccc(Br)cn3)[C@H](C)c3ncccn3)cc2nc1N
|
C21H20BrN7O 466.343000 |
JKULQMNXTLIXNY-CYBMUJFWSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703963; PubChem:CID172487106
|
Local ready
Direct docking supported
|
|
E3L035037
BDB035037
|
US20240368153, Example 10-11
Cc1cc(N)nc2cc(C(=O)N(Cc3ccc(Br)cn3)[C@@H](C)c3ncccn3)cnc12
|
C22H20BrN7O 478.354000 |
LPMWBYYNVIELIY-AWEZNQCLSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703964; PubChem:CID166460558
|
Local ready
Direct docking supported
|
|
E3L035038
BDB035038
|
US20240368153, Example 10-2
Cc1cc2[nH]c(C(=O)N(Cc3ccc(Br)cn3)[C@@H](C)c3ncccn3)cc2nc1N
|
C21H20BrN7O 466.343000 |
JKULQMNXTLIXNY-ZDUSSCGKSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703965; PubChem:CID172487052
|
Local ready
Direct docking supported
|
|
E3L035039
BDB035039
|
US20240368153, Example 10-3
Cc1cc2[nH]c(C(=O)N(Cc3ccc(C(F)(F)F)cn3)C3CCCc4nccnc43)cc2nc1N
|
C24H22F3N7O 481.482000 |
KIEKGAQRUFUIEQ-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703966; PubChem:CID172487121
|
Local ready
Direct docking supported
|
|
E3L035040
BDB035040
|
US20240368153, Example 10-4
Cc1cc2[nH]c(C(=O)N(Cc3ccc(C(F)(F)F)cn3)[C@H]3CCCc4nccnc43)cc2nc1N
|
C24H22F3N7O 481.482000 |
KIEKGAQRUFUIEQ-FQEVSTJZSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM703967; PubChem:CID172487087
|
Local ready
Direct docking supported
|