| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035341
BDB035341
|
US20250002493, Embodiment 34
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C24H30F2N4O3 460.525000 |
RXOHLWJHZMWCHG-LHSJRXKWSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710515; PubChem:CID175664849
|
Local ready
Direct docking supported
|
|
E3L035342
BDB035342
|
US20250002493, Embodiment 36
[2H]C([2H])([2H])N[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C24H30F2N4O3 463.543305 |
RXOHLWJHZMWCHG-PCFZCQRFSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710516; PubChem:CID175664850
|
Local ready
Direct docking supported
|
|
E3L035343
BDB035343
|
US20250002493, Embodiment 37
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(=O)n(Cc3ccc(F)cc3O)cc21)C(C)(C)C
|
C24H31FN4O4 458.534000 |
UVQSBDIUHLPFAC-LHSJRXKWSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710517; PubChem:CID175664851
|
Local ready
Direct docking supported
|
|
E3L035344
BDB035344
|
US20250002493, Embodiment 40
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C26H34F2N4O3 488.579000 |
VMJKIHXOXYMIQM-OYHNWAKOSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710518; PubChem:CID175664852
|
Local ready
Direct docking supported
|
|
E3L035345
BDB035345
|
US20250002493, Embodiment 41
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3F)cc21)C1CCCCC1
|
C28H36F2N4O3 514.617000 |
IROQAXMCBOSTSD-GKVSMKOHSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710519; PubChem:CID175664853
|
Local ready
Direct docking supported
|
|
E3L035346
BDB035346
|
US20250002493, Embodiment 42
[2H]C([2H])([2H])N[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C26H34F2N4O3 491.597305 |
VMJKIHXOXYMIQM-MUSUWNGGSA-N | P98170, Q13489, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM710520; PubChem:CID175664854
|
Local ready
Direct docking supported
|
|
E3L035347
BDB035347
|
US20250002493, Embodiment 43
[2H]C([2H])([2H])N[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3)cc21)C(C)(C)C
|
C26H35FN4O3 473.607305 |
IOXDPORQGXSQNR-YVHHVTFOSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710521; PubChem:CID175664855
|
Local ready
Direct docking supported
|
|
E3L035348
BDB035348
|
US20250002493, Embodiment 46
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3O)cc21)C(C)(C)C
|
C26H35FN4O4 486.588000 |
WTKYDJFAEKJLOZ-OYHNWAKOSA-N | P98170, Q13489, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710522; PubChem:CID175664856
|
Local ready
Direct docking supported
|
|
E3L035349
BDB035349
|
US20250002493, Embodiment 47
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3)cc21)C(C)(C)C
|
C26H35FN4O3 470.589000 |
IOXDPORQGXSQNR-KSFYIVLOSA-N | P98170, Q13489, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM710523; PubChem:CID175664857
|
Local ready
Direct docking supported
|
|
E3L035350
BDB035350
|
US20250002493, Embodiment 48
C[C@H](N)C(=O)N[C@H](C(=O)N1CCc2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C23H28F2N4O3 446.498000 |
XIEJPDYRXBCDGY-RNODOKPDSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710524; PubChem:CID175664858
|
Local ready
Direct docking supported
|
|
E3L035351
BDB035351
|
US20250002493, Embodiment 36
[2H]C([2H])([2H])N[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C24H30F2N4O3 463.543305 |
RXOHLWJHZMWCHG-PCFZCQRFSA-N | P98170, Q13489, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710525; PubChem:CID175664850
|
Local ready
Direct docking supported
|
|
E3L035352
BDB035352
|
US20250002493, Embodiment 50
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1)c(=O)n2C)C1CCCCC1
|
C27H35FN4O3 482.600000 |
GVAUTEQHOXIAJI-XDHUDOTRSA-N | P98170, Q13489, Q13490 | E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710526; PubChem:CID171559273
|
Local ready
Direct docking supported
|
|
E3L035353
BDB035353
|
US20250002493, Embodiment 51
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1)c(=O)n2C)C(C)(C)C
|
C25H33FN4O3 456.562000 |
MNGUBMKVFGTZKL-YCRPNKLZSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710527; PubChem:CID175664859
|
Local ready
Direct docking supported
|
|
E3L035354
BDB035354
|
US20250002493, Embodiment 52
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1F)c(=O)n2C)C(C)(C)C
|
C25H32F2N4O3 474.552000 |
GSYCIPSRQKSJPJ-LHSJRXKWSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM710528; PubChem:CID175664860
|
Local ready
Direct docking supported
|
|
E3L035355
BDB035355
|
US20250002493, Embodiment 55
CCn1c2c(cc(Cc3ccc(F)cc3F)c1=O)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)CC2
|
C26H34F2N4O3 488.579000 |
XVRNAIWVXGNREC-OYHNWAKOSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710529; PubChem:CID175664861
|
Local ready
Direct docking supported
|
|
E3L035356
BDB035356
|
US20250002493, Embodiment 56
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2c1cc(Cc1ccc(F)cc1F)c(=O)n2C)C(C)(C)C
|
C27H36F2N4O3 502.606000 |
QCYGMXHLGJJCRO-YCRPNKLZSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710530; PubChem:CID175664862
|
Local ready
Direct docking supported
|
|
E3L035357
BDB035357
|
US20250002493, Embodiment 57
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1F)c(=O)n2CC(F)(F)F)C(C)(C)C
|
C26H31F5N4O3 542.549000 |
FLOFERYEJWPXFA-LHSJRXKWSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710531; PubChem:CID175664863
|
Local ready
Direct docking supported
|
|
E3L035358
BDB035358
|
US20250002493, Embodiment 59
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2[nH]c(=O)c(Cc3ccc(F)cc3)cc21)C1CCCCC1
|
C26H33FN4O3 468.573000 |
AATYEYGQEXDYIH-HJPURHCSSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB, PubChem
BindingDB:BDBM710532; PubChem:CID171559280
|
Local ready
Direct docking supported
|
|
E3L035359
BDB035359
|
US20250002493, Embodiment 60
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2[nH]c(=O)c(Cc3ccc(F)cc3F)cc21)C(C)(C)C
|
C24H30F2N4O3 460.525000 |
YSDXUKHVYYZKGA-RNODOKPDSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 3 |
BindingDB, PubChem
BindingDB:BDBM710533; PubChem:CID175664864
|
Local ready
Direct docking supported
|
|
E3L035360
BDB035360
|
US20250002493, Embodiment 61
CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2[nH]c(=O)c(Cc3ccc(F)cc3)cc21)C(C)(C)C
|
C24H31FN4O3 442.535000 |
SBCXEQHIGXRICU-VBKZILBWSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 2 |
BindingDB, PubChem
BindingDB:BDBM710534; PubChem:CID175664865
|
Local ready
Direct docking supported
|