| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035301
BDB035301
|
US20240425497, Example 27
CC(O)c1cc2ncn(-c3cc(-c4ccc(F)cc4C(=O)N4CC(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C26H23F2N5O3 491.498000 |
YZMFBIBDXAICNY-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708699; PubChem:CID172580974
|
Local ready
Direct docking supported
|
|
E3L035302
BDB035302
|
US20240425497, Example 28
C[C@H]1CCCN(Cc2ccc3c(c2)C(=O)N(c2cc(-c4ccc(F)cc4C(=O)N4CC(F)C4)cc(C4CC4)n2)C3)C1
|
C33H34F2N4O2 556.657000 |
KQNGDIMKEPAFKN-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708700; PubChem:CID175664530
|
Local ready
Direct docking supported
|
|
E3L035303
BDB035303
|
US20240425497, Example 29
C[C@H]1CCCN(Cc2nc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)c4)c(=O)c3[nH]2)C1
|
C35H37F2N5O2 597.710000 |
QFBDNXLFERNEMB-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708701; PubChem:CID175664531
|
Local ready
Direct docking supported
|
|
E3L035304
BDB035304
|
US20240425497, Example 30
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)nc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C34H36F2N6O2 598.698000 |
HUNANKZDYDLWMZ-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708702; PubChem:CID172580931
|
Local ready
Direct docking supported
|
|
E3L035305
BDB035305
|
US20240425497, Example 31
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4nc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C34H36F2N6O2 598.698000 |
GTCAUSNTJKVVRO-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708703; PubChem:CID172581050
|
Local ready
Direct docking supported
|
|
E3L035306
BDB035306
|
US20240425497, Example 32
O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cnc3cc(C4CCNC4)[nH]c3c2=O)n1)N1CC(F)C1
|
C27H25F2N7O2 517.540000 |
CGTNFINAXRFRND-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708704; PubChem:CID175664532
|
Local ready
Direct docking supported
|
|
E3L035307
BDB035307
|
US20240425497, Example 33
O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cnc3cc(C4CC4)[nH]c3c2=O)n1)N1CC(F)C1
|
C26H22F2N6O2 488.498000 |
KAEYWZNFFLKDFF-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708705; PubChem:CID175664533
|
Local ready
Direct docking supported
|
|
E3L035308
BDB035308
|
US20240425497, Example 34
COC[C@H](C)NCc1cc2ncn(-c3nc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C28H28F3N7O3 567.572000 |
PVSQRVKDSIYQEQ-HNNXBMFYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708706; PubChem:CID175664534
|
Local ready
Direct docking supported
|
|
E3L035309
BDB035309
|
US20240425497, Example 35
COCCNCc1cc2ncn(-c3nc(-c4ccc(F)cc4C(=O)N4CC(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C27H27F2N7O3 535.555000 |
YEIOAIQLMZBUFU-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708707; PubChem:CID175664535
|
Local ready
Direct docking supported
|
|
E3L035310
BDB035310
|
US20240425497, Example 36
CC1(NCc2cc3ncn(-c4nc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)CCC1
|
C29H29F2N7O2 545.594000 |
TXYRJMIDPSWECS-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708708; PubChem:CID175664536
|
Local ready
Direct docking supported
|
|
E3L035311
BDB035311
|
US20240425497, Example 37
O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cnc3cc(CN4CC5CCC4C5)[nH]c3c2=O)n1)N1CC(F)C1
|
C30H29F2N7O2 557.605000 |
JXJWLRATYWQHJW-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708709; PubChem:CID175664537
|
Local ready
Direct docking supported
|
|
E3L035312
BDB035312
|
US20240425497, Example 38
COCCN(C)Cc1cc2ncn(-c3nc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C28H28F3N7O3 567.572000 |
LVDJPMFLNVMYKO-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708710; PubChem:CID175664538
|
Local ready
Direct docking supported
|
|
E3L035313
BDB035313
|
US20240425497, Example 39
O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cnc3cc(CNCCC(F)(F)F)[nH]c3c2=O)n1)N1CC(F)(F)C1
|
C27H23F6N7O2 591.516000 |
XDVFOHLNZZAXDD-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708711; PubChem:CID175664539
|
Local ready
Direct docking supported
|
|
E3L035314
BDB035314
|
US20240425497, Example 40
COC(C)CN(C)Cc1cc2ncn(-c3nc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C29H30F3N7O3 581.599000 |
YBQFWKKVTYVLCO-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708712; PubChem:CID175664540
|
Local ready
Direct docking supported
|
|
E3L035315
BDB035315
|
US20240425497, Example 41
COCCNCc1cc2ncn(-c3cc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)c3)c(=O)c2[nH]1
|
C29H28F3N5O3 551.569000 |
NFDUIRMFJGYTKC-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708713; PubChem:CID172581008
|
Local ready
Direct docking supported
|
|
E3L035316
BDB035316
|
US20240425497, Example 42
CC(C)CNCc1cc2ncn(-c3cc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)c3)c(=O)c2[nH]1
|
C30H30F3N5O2 549.597000 |
WIFMNQNANNJGKS-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708714; PubChem:CID175664541
|
Local ready
Direct docking supported
|
|
E3L035317
BDB035317
|
US20240425497, Example 43
COC1CN(Cc2cc3ncn(-c4nc(-c5ccc(F)cc5C(=O)N5CC(F)(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C28H26F3N7O3 565.556000 |
XMXMMMXLOMNCFL-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708715; PubChem:CID175664542
|
Local ready
Direct docking supported
|
|
E3L035318
BDB035318
|
US20240425497, Example 44
COCCNCc1cc2ncn(-c3cc(-c4ccc(F)cc4C(=O)N4CC(F)(F)C4)cc(C4CC4)n3)c(=O)c2[nH]1
|
C28H27F3N6O3 552.557000 |
IJGIVXJCIHSTKL-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708716; PubChem:CID172580938
|
Local ready
Direct docking supported
|
|
E3L035319
BDB035319
|
US20240425497, Example 45
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cc(-c5c(C(=O)N6CC(F)C6)cnn5C)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C31H33FN8O2 568.657000 |
HEKNRJKRJWAAJH-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708717; PubChem:CID172580965
|
Local ready
Direct docking supported
|
|
E3L035320
BDB035320
|
US20240425497, Example 46
C[C@H]1CCCN(Cc2[nH]c3c(=O)n(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)cc(C#N)c3c2Cl)C1
|
C33H31ClF2N6O2 617.100000 |
CWISDHDYZGKEDN-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708718; PubChem:CID172581033
|
Local ready
Direct docking supported
|