| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L035281
BDB035281
|
US20240425497, Example 7
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CCC5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C35H38FN5O2 579.720000 |
LIUKNSYJXUPILB-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708679; PubChem:CID175664511
|
Local ready
Direct docking supported
|
|
E3L035282
BDB035282
|
US20240425497, Example 8
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N(C)c5ccccc5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C39H40FN5O2 629.780000 |
OWDGGJNHLQDRBR-DEOSSOPVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708680; PubChem:CID175664512
|
Local ready
Direct docking supported
|
|
E3L035283
BDB035283
|
US20240425497, Example 9
CC1CCCN1C(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C37H42FN5O2 607.774000 |
UMKHZKIKXPVVTD-NQCNTLBGSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708681; PubChem:CID175664513
|
Local ready
Direct docking supported
|
|
E3L035284
BDB035284
|
US20240425497, Example 10
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C35H37F2N5O2 597.710000 |
FYWOHFARPIKGPQ-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708682; PubChem:CID175664514
|
Local ready
Direct docking supported
|
|
E3L035285
BDB035285
|
US20240425497, Example 11
COC1CN(C(=O)c2cc(F)ccc2-c2cc(C3CC3)nc(-n3cc(C4CC4)c4cc(CN5CCC[C@H](C)C5)[nH]c4c3=O)c2)C1
|
C36H40FN5O3 609.746000 |
JERQGUQVKBOKAG-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708683; PubChem:CID175664515
|
Local ready
Direct docking supported
|
|
E3L035286
BDB035286
|
US20240425497, Example 12
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)NCC(F)(F)F)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C34H35F4N5O2 621.679000 |
YMEHCLAZRGPREA-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708684; PubChem:CID175664516
|
Local ready
Direct docking supported
|
|
E3L035287
BDB035287
|
US20240425497, Example 13
CCN(C)C(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C35H40FN5O2 581.736000 |
HQTQWFUZMXUWBL-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708685; PubChem:CID175664517
|
Local ready
Direct docking supported
|
|
E3L035288
BDB035288
|
US20240425497, Example 14
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C35H36F3N5O2 615.700000 |
WZXWHIPYOZGHSD-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708686; PubChem:CID175664518
|
Local ready
Direct docking supported
|
|
E3L035289
BDB035289
|
US20240425497, Example 15
CC1CCN1C(=O)c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN4CCC[C@H](C)C4)[nH]c3c2=O)c1
|
C36H40FN5O2 593.747000 |
QXVBZZXZQNESOU-HMTLIYDFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708687; PubChem:CID175664519
|
Local ready
Direct docking supported
|
|
E3L035290
BDB035290
|
US20240425497, Example 16
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(C#N)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C36H37FN6O2 604.730000 |
LQWBNPACLKJMHI-NRFANRHFSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708688; PubChem:CID175664520
|
Local ready
Direct docking supported
|
|
E3L035291
BDB035291
|
US20240425497, Example 17
O=C(c1cc(F)ccc1-c1cc(C2CC2)nc(-n2cc(C3CC3)c3cc(CN[C@H]4CCC[C@H]4O)[nH]c3c2=O)c1)N1CC(F)C1
|
C34H35F2N5O3 599.682000 |
ZIVURWZDKSUWJU-MFMCTBQISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708689; PubChem:CID175664521
|
Local ready
Direct docking supported
|
|
E3L035292
BDB035292
|
US20240425497, Example 18
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(N)=O)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C32H34FN5O2 539.655000 |
ZIRQKNBBULUWQV-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708690; PubChem:CID175664522
|
Local ready
Direct docking supported
|
|
E3L035293
BDB035293
|
US20240425497, Example 19
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cc(-c5ccc(F)c(F)c5C(=O)N(C)C)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C32H32F2N6O2 570.644000 |
RQUIFABMUUDUEF-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708691; PubChem:CID175664523
|
Local ready
Direct docking supported
|
|
E3L035294
BDB035294
|
US20240425497, Example 20
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cc(-c5cccnc5C(=O)N(C)C)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C31H33N7O2 535.652000 |
IGCGXTYVWZTOCU-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708692; PubChem:CID175664524
|
Local ready
Direct docking supported
|
|
E3L035295
BDB035295
|
US20240425497, Example 10
C[C@H]1CCCN(Cc2cc3c(C4CC4)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C35H37F2N5O2 597.710000 |
FYWOHFARPIKGPQ-FQEVSTJZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708693; PubChem:CID175664514
|
Local ready
Direct docking supported
|
|
E3L035296
BDB035296
|
US20240425497, Example 22
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C33H32F2N6O2 582.655000 |
WYRFVVKZGLXAJM-IBGZPJMESA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708694; PubChem:CID175664525
|
Local ready
Direct docking supported
|
|
E3L035297
BDB035297
|
US20240425497, Example 23
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C(F)(F)F)c4)c(=O)c3[nH]2)C1
|
C32H28F5N5O2 609.599000 |
QSNRHGNCFJVAFZ-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708695; PubChem:CID175664526
|
Local ready
Direct docking supported
|
|
E3L035298
BDB035298
|
US20240425497, Example 24
C[C@H]1CCCN(Cc2cc3c(C#N)cn(-c4cncc(-c5ccc(F)cc5C(=O)N5CC(F)C5)c4)c(=O)c3[nH]2)C1
|
C30H28F2N6O2 542.590000 |
HNTBSHAJVKEDGY-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708696; PubChem:CID175664527
|
Local ready
Direct docking supported
|
|
E3L035299
BDB035299
|
US20240425497, Example 25
C[C@H]1CCCN(Cc2cc3ncn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)C1
|
C31H32F2N6O2 558.633000 |
RBYXXODLFATXOK-SFHVURJKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708697; PubChem:CID175664528
|
Local ready
Direct docking supported
|
|
E3L035300
BDB035300
|
US20240425497, Example 26
C[C@@H]1CN(Cc2cc3ncn(-c4cc(-c5ccc(F)cc5C(=O)N5CC(F)C5)cc(C5CC5)n4)c(=O)c3[nH]2)CCO1
|
C30H30F2N6O3 560.605000 |
DCJZZYVMLVNJRY-QGZVFWFLSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM708698; PubChem:CID175664529
|
Local ready
Direct docking supported
|