| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041041
BDB041041
|
US12409171, Regno SJ000399589
Cc1nn(C)c2c1[C@@H](c1ccc(F)c(F)c1)[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)N2
|
C21H17ClF2N4O2 430.842000 |
HDCGWBRRTUKVDZ-MSOLQXFVSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768592; PubChem:CID135558184
|
Local ready
Direct docking supported
|
|
E3L041042
BDB041042
|
US12409171, Regno SJ000399597
COc1cccc([C@@H]2c3c(C)nn(C)c3NC(=O)[C@H]2NC(=O)c2cccc(C)c2)c1
|
C23H24N4O3 404.470000 |
COCUYUKSQBIZMV-UXHICEINSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768593; PubChem:CID135560723
|
Local ready
Direct docking supported
|
|
E3L041043
BDB041043
|
US12409171, Regno SJ000399598
Cc1nn(C)c2c1[C@@H](c1cccc(Cl)c1)[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)N2
|
C21H18Cl2N4O2 429.307000 |
BHOBWLLSKXWOOQ-MSOLQXFVSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768594; PubChem:CID135558182
|
Local ready
Direct docking supported
|
|
E3L041044
BDB041044
|
US12409171, Regno SJ000399608
COc1ccc([C@@H]2c3c(C)nn(C)c3NC(=O)[C@H]2NC(=O)c2ccccc2)cc1OC
|
C23H24N4O4 420.469000 |
YGBMBMLDDMJKCW-UXHICEINSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768595; PubChem:CID135560720
|
Local ready
Direct docking supported
|
|
E3L041045
BDB041045
|
US12409171, Regno SJ000399617
COc1ccc(C(=O)N[C@@H]2C(=O)Nc3c(c(C)nn3C)[C@H]2c2ccc(Cl)c(Cl)c2)cc1OC
|
C23H22Cl2N4O4 489.359000 |
PGIWPEVINZXEAK-UXHICEINSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768596; PubChem:CID135558191
|
Local ready
Direct docking supported
|
|
E3L041046
BDB041046
|
US12409171, Regno SJ000401391
COc1ccc([C@@H]2c3c(C)nn(C)c3NC(=O)[C@H]2NC(=O)c2ccc(Cl)cc2)cc1F
|
C22H20ClFN4O3 442.878000 |
PPFIVHUZJXJOQR-MOPGFXCFSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768597; PubChem:CID135558150
|
Local ready
Direct docking supported
|
|
E3L041047
BDB041047
|
US12409171, Regno SJ000401421
Cc1cccc(C(=O)N[C@@H]2C(=O)Nc3c(c(C)nn3C)[C@H]2c2cccc(C)c2)c1
|
C23H24N4O2 388.471000 |
MJSHFUBKKVJNIW-UXHICEINSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768598; PubChem:CID135616628
|
Local ready
Direct docking supported
|
|
E3L041048
BDB041048
|
US12409171, Regno SJ000401460
Cc1ccc([C@@H]2c3c(C)nn(C)c3NC(=O)[C@H]2NC(=O)c2ccccc2)cc1
|
C22H22N4O2 374.444000 |
ATJZAEHYKNGXDH-MOPGFXCFSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM768599; PubChem:CID135616624
|
Local ready
Direct docking supported
|
|
E3L041049
BDB041049
|
4-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)benzoic acid
O=C(O)c1ccc(Nc2ncnc3[nH]ccc23)cc1
|
C13H10N4O2 254.249000 |
VANCFSVKVVIWBL-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM769293; PubChem:CID24958299
|
Local ready
Direct docking supported
|
|
E3L041050
BDB041050
|
N-(1H-pyrazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
c1cc(Nc2ncnc3[nH]ccc23)[nH]n1
|
C9H8N6 200.205000 |
BHRDBYKSAWCZPD-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM769498; PubChem:CID177821835
|
Local ready
Direct docking supported
|
|
E3L041051
BDB041051
|
BDBM771446
COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cccc(Cl)c2)C3=O)c(OC)n1
|
C28H23Cl2N5O4 564.429000 |
PPPFDJZVGJPNBJ-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771446
|
Local ready
Direct docking supported
|
|
E3L041052
BDB041052
|
BDBM771455
COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)ccc2F)C3=O)c(OC)n1
|
C28H22Cl2FN5O4 582.419000 |
GOASEPABROQYQN-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771455
|
Local ready
Direct docking supported
|
|
E3L041053
BDB041053
|
BDBM771493
COc1nc(OC)c(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1
|
C30H27Cl2N5O5 608.482000 |
KVAIMTUGKJNIDH-PMERELPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771493
|
Local ready
Direct docking supported
|
|
E3L041054
BDB041054
|
BDBM771499
COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1
|
C28H22Cl2FN5O4 582.419000 |
CIGZPEKVMCPFJL-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771499
|
Local ready
Direct docking supported
|
|
E3L041055
BDB041055
|
BDBM771500
COc1nc(OC)c(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)ccc2F)C3=O)c(OC)n1
|
C29H24Cl2FN5O5 612.445000 |
ZKGBGDQWGKBHIQ-LJAQVGFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771500
|
Local ready
Direct docking supported
|
|
E3L041056
BDB041056
|
BDBM771518
COc1cc(N(C)C)ncc1-n1cc2c(c1C(C)C)[C@@]1(C(=O)Nc3cc(Cl)ccc31)N(c1cc(Cl)ccc1F)C2=O
|
C30H26Cl2FN5O3 594.474000 |
QFMOAQDUPNHDQU-PMERELPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771518
|
Local ready
Direct docking supported
|
|
E3L041057
BDB041057
|
BDBM771519
COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2ccc(F)c(F)c2)C3=O)c(OC)n1
|
C28H22ClF2N5O4 565.964000 |
WDLFXRNLWVHTRX-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771519
|
Local ready
Direct docking supported
|
|
E3L041058
BDB041058
|
BDBM771521
COc1cc(OC)c(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2ccc(F)c(F)c2)C3=O)cn1
|
C29H23ClF2N4O4 564.976000 |
GUWKEWLBMRPRJD-LJAQVGFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771521
|
Local ready
Direct docking supported
|
|
E3L041059
BDB041059
|
BDBM771522
COc1cc(OC)c(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)ccc2F)C3=O)cn1
|
C29H23Cl2FN4O4 581.431000 |
YGSKZZUWMCCSHM-LJAQVGFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771522
|
Local ready
Direct docking supported
|
|
E3L041060
BDB041060
|
BDBM771573
COc1ncc(-n2cc3c(c2C(C)C)[C@@]2(C(=O)Nc4cc(Cl)ccc42)N(c2cc(Cl)c(F)cc2F)C3=O)c(OC)n1
|
C28H21Cl2F2N5O4 600.409000 |
FEEFTWRYZPBKGX-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771573
|
Local ready
Direct docking supported
|