| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041081
BDB041081
|
US20250289799, Example 24
CC(C)c1ccccc1-c1ncc2c(n1)N(CC1CCN(c3nc(C(F)(F)F)cn3C)CC1)C(=O)CO2
|
C26H29F3N6O2 514.552000 |
YZUBMVZJIYLDLJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771882; PubChem:CID176244100
|
Local ready
Direct docking supported
|
|
E3L041082
BDB041082
|
US20250289799, Example 25
CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCC2CCN(c3nc(C(F)(F)F)cn3C)CC2)n1
|
C25H28F6N6 526.529000 |
GWVBQRLHRASJCD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771883; PubChem:CID176244145
|
Local ready
Direct docking supported
|
|
E3L041083
BDB041083
|
US20250289799, Example 26
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C25H24F3N7O2 511.508000 |
MGWPSNSQUYAKGH-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771884; PubChem:CID176244318
|
Local ready
Direct docking supported
|
|
E3L041084
BDB041084
|
US20250289799, Example 27
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nccn3ccnc23)cc1
|
C26H24N8O2 480.532000 |
UABPBADOLVMDIH-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771885; PubChem:CID176244130
|
Local ready
Direct docking supported
|
|
E3L041085
BDB041085
|
US20250289799, Example 28
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCC12CCC(c3ccc(C(F)(F)F)cn3)(CC1)CC2
|
C28H31F3N6O2 540.590000 |
ABUACTIZORDXRT-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771886; PubChem:CID177269278
|
Local ready
Direct docking supported
|
|
E3L041086
BDB041086
|
US20250289799, Example 29
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C25H24F3N7O2 511.508000 |
GUVUYALCVUAQLY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771887; PubChem:CID176244111
|
Local ready
Direct docking supported
|
|
E3L041087
BDB041087
|
US20250289799, Example 30
COc1ncnc(C2CC2)c1-c1ncc2c(n1)N(CC1CCN(c3nc(C(F)(F)F)cn3C)CC1)C(=O)CO2
|
C25H27F3N8O3 544.538000 |
WSZCEHJUCDSGHN-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771888; PubChem:CID176244103
|
Local ready
Direct docking supported
|
|
E3L041088
BDB041088
|
US20250289799, Example 32
CC(C)c1ccccc1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2occc2n1
|
C27H24N4O 420.516000 |
CDOBKBJITRLYHK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771889; PubChem:CID170316882
|
Local ready
Direct docking supported
|
|
E3L041089
BDB041089
|
US20250289799, Example 33
CC(C)c1ccccc1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2occc2n1
|
C27H24F3N5O 491.517000 |
YGCPCELOCNSUOX-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771890; PubChem:CID176244129
|
Local ready
Direct docking supported
|
|
E3L041090
BDB041090
|
US20250289799, Example 34
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2occc2n1
|
C26H22N6O2 450.502000 |
FUILBVIYSXMSRX-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771891; PubChem:CID176244219
|
Local ready
Direct docking supported
|
|
E3L041091
BDB041091
|
US20250289799, Example 35
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2occc2n1
|
C26H22F3N7O2 521.503000 |
AWLAWJHEVPPSKK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771892; PubChem:CID176244090
|
Local ready
Direct docking supported
|
|
E3L041092
BDB041092
|
US20250289799, Example 36
CC(C)c1ccccc1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]ccc2n1
|
C27H25N5 419.532000 |
XOFAOBUJVLMYQJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771893; PubChem:CID176244118
|
Local ready
Direct docking supported
|
|
E3L041093
BDB041093
|
US20250289799, Example 37
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]ccc2n1
|
C26H23N7O 449.518000 |
PPSJXZQVBVKSBJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771894; PubChem:CID176244162
|
Local ready
Direct docking supported
|
|
E3L041094
BDB041094
|
US20250289799, Example 38
CC(C)c1ccccc1-c1ncc(C#N)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C26H23F3N6 476.506000 |
IECVALNNFYDFDL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771895; PubChem:CID165406236
|
Local ready
Direct docking supported
|
|
E3L041095
BDB041095
|
US20250289799, Example 38
CC(C)c1ccccc1-c1ncc(C#N)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C26H23F3N6 476.506000 |
IECVALNNFYDFDL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771896; PubChem:CID165406236
|
Local ready
Direct docking supported
|
|
E3L041096
BDB041096
|
US20250289799, Example 40
CC(C)c1ccccc1-c1nc(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2ncccc2n1
|
C28H25F3N6 502.544000 |
LNLCPDZGLXKIFI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771897; PubChem:CID176244146
|
Local ready
Direct docking supported
|
|
E3L041097
BDB041097
|
US20250289799, Example 41
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C28H29N5O4 499.571000 |
FUJBQMDQMGTBEO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771898; PubChem:CID176244135
|
Local ready
Direct docking supported
|
|
E3L041098
BDB041098
|
US20250289799, Example 50
COc1ncnc(C2CC2)c1-c1nc(NCc2ccc(-n3nc(C(F)(F)F)cc3C)cc2)c2occc2n1
|
C26H22F3N7O2 521.503000 |
GCJRMTHRUBHEIJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771899; PubChem:CID176244150
|
Local ready
Direct docking supported
|
|
E3L041099
BDB041099
|
US20250289799, Example 57
Cc1cc(C(F)(F)F)nn1-c1ccc(CNc2nc(-c3ccccc3C(C)C)nc3ccoc23)cc1
|
C27H24F3N5O 491.517000 |
MQEUBGQUDPWPDS-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771900; PubChem:CID176244128
|
Local ready
Direct docking supported
|
|
E3L041100
BDB041100
|
US20250289799, Example 61
COc1cnc(-c2ccccc2C(C)C)nc1N(C)CC1CCC(c2ccccn2)CC1
|
C27H34N4O 430.596000 |
CPALDWUNJYGGLG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771901; PubChem:CID175444698
|
Local ready
Direct docking supported
|