| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041101
BDB041101
|
US20250289799, Example 62
COc1cnc(-c2ccccc2C(C)C)nc1N(C)CC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C26H33F3N6O 502.585000 |
KSBAHZNCYBJXGZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771902; PubChem:CID176244120
|
Local ready
Direct docking supported
|
|
E3L041102
BDB041102
|
US20250289799, Example 63
COc1cnc(-c2ccccc2C(C)C)nc1NCC1CCC(c2ccccn2)CC1
|
C26H32N4O 416.569000 |
LUOJDMDAHOHUQE-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771903; PubChem:CID176244234
|
Local ready
Direct docking supported
|
|
E3L041103
BDB041103
|
US20250289799, Example 64
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2ccccn2)cc1
|
C26H26N4O 410.521000 |
VQFCZYWIHDUCDO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771904; PubChem:CID176244250
|
Local ready
Direct docking supported
|
|
E3L041104
BDB041104
|
US20250289799, Example 65
COc1cnc(-c2ccccc2C(C)C)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C25H31F3N6O 488.558000 |
ZLESCTLYTHEAOI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771905; PubChem:CID176244307
|
Local ready
Direct docking supported
|
|
E3L041105
BDB041105
|
US20250289799, Example 66
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2ccc(C)cn2)cc1
|
C27H28N4O 424.548000 |
LQSFUFNARNYQDQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771906; PubChem:CID176244182
|
Local ready
Direct docking supported
|
|
E3L041106
BDB041106
|
US20250289799, Example 67
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(OCc2ccccn2)cc1
|
C27H28N4O2 440.547000 |
DQLQLFNWTQBOPA-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771907; PubChem:CID176244139
|
Local ready
Direct docking supported
|
|
E3L041107
BDB041107
|
US20250289799, Example 68
CCOCCOc1ccc(CNc2nc(-c3ccccc3C(C)C)ncc2OC)cc1
|
C25H31N3O3 421.541000 |
KMRFRQIVZPNTCB-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771908; PubChem:CID176244273
|
Local ready
Direct docking supported
|
|
E3L041108
BDB041108
|
US20250289799, Example 69
COc1cc(CNc2nc(-c3ccccc3C(C)C)ncc2OC)ccc1-n1nc(C(F)(F)F)cc1C
|
C27H28F3N5O2 511.548000 |
IVLUJVHHAGCAJL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771909; PubChem:CID176244093
|
Local ready
Direct docking supported
|
|
E3L041109
BDB041109
|
US20250289799, Example 70
CC(C)Oc1cnc(-c2ccccc2C(C)C)nc1N(C)CC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C28H37F3N6O 530.639000 |
BILZOJNMERVIPN-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771910; PubChem:CID176244168
|
Local ready
Direct docking supported
|
|
E3L041110
BDB041110
|
US20250289799, Example 71
CC(C)Oc1cnc(-c2ccccc2C(C)C)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C29H32F3N5O 523.603000 |
XHBMBVUKKCOXII-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771911; PubChem:CID176244243
|
Local ready
Direct docking supported
|
|
E3L041111
BDB041111
|
US20250289799, Example 72
CC(C)Oc1cnc(-c2ccccc2C(C)C)nc1NCC1CCN(c2nc(C(F)(F)F)cn2C)CC1
|
C27H35F3N6O 516.612000 |
GMDOICJFPHZINJ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771912; PubChem:CID176244281
|
Local ready
Direct docking supported
|
|
E3L041112
BDB041112
|
US20250289799, Example 73
CC(C)Oc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C28H30F3N5O 509.576000 |
XWCWKBLMQAMNMQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771913; PubChem:CID176244164
|
Local ready
Direct docking supported
|
|
E3L041113
BDB041113
|
US20250289799, Example 74
CC(C)Oc1cnc(-c2ccccc2C(C)C)nc1NCC12CCC(c3ccc(C(F)(F)F)cn3)(CC1)CC2
|
C31H37F3N4O 538.658000 |
DSJYMTJZBFSCGI-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771914; PubChem:CID176244108
|
Local ready
Direct docking supported
|
|
E3L041114
BDB041114
|
US20250289799, Example 25
CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCC2CCN(c3nc(C(F)(F)F)cn3C)CC2)n1
|
C25H28F6N6 526.529000 |
GWVBQRLHRASJCD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771915; PubChem:CID176244145
|
Local ready
Direct docking supported
|
|
E3L041115
BDB041115
|
US20250289799, Example 76
CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCC2CCN(c3ccccn3)CC2)n1
|
C25H28F3N5 455.528000 |
VBBYRXYMOQJZPK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771916; PubChem:CID176244112
|
Local ready
Direct docking supported
|
|
E3L041116
BDB041116
|
US20250289799, Example 77
CC(C)c1ccccc1-c1nc(NCc2ccc3c(c2)CCN(C)C3=O)c2occc2n1
|
C26H26N4O2 426.520000 |
IWUYLZJTWCWSGY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771917; PubChem:CID176244194
|
Local ready
Direct docking supported
|
|
E3L041117
BDB041117
|
US20250289799, Example 78
CC(C)c1ccccc1-c1nc(NCc2ccc3c(c2)CCN(C(C)C)C3=O)c2occc2n1
|
C28H30N4O2 454.574000 |
UQYGBEHVVXOPBR-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771918; PubChem:CID176244159
|
Local ready
Direct docking supported
|
|
E3L041118
BDB041118
|
US20250289799, Example 79
CCOCCOc1ccc(CNc2nc(-c3ccccc3C(C)C)nc3ccoc23)cc1
|
C26H29N3O3 431.536000 |
ODOPLSZJERKDBL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771919; PubChem:CID176244089
|
Local ready
Direct docking supported
|
|
E3L041119
BDB041119
|
US20250289799, Example 80
COC1CC(Oc2ccc(CNc3nc(-c4ccccc4C(C)C)nc4ccoc34)cc2)C1
|
C27H29N3O3 443.547000 |
ARAJFCDWIZGRMF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771920; PubChem:CID176244165
|
Local ready
Direct docking supported
|
|
E3L041120
BDB041120
|
US20250289799, Example 81
COc1cc(-c2nc(C(F)(F)F)cn2C)ccc1CNc1nc(-c2ccccc2C(C)C)nc2ccoc12
|
C28H26F3N5O2 521.543000 |
QZOUMWWCRNMTFD-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771921; PubChem:CID176244147
|
Local ready
Direct docking supported
|