| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041061
BDB041061
|
BDBM771574
CCC(C)c1c2c(cn1-c1cnc(OC)nc1OC)C(=O)N(c1cc(Cl)ccc1F)[C@]21C(=O)Nc2cc(Cl)ccc21
|
C29H24Cl2FN5O4 596.446000 |
VCYMIRMEWQHYHV-LKFCVPRCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM771574
|
Local ready
Direct docking supported
|
|
E3L041062
BDB041062
|
US20250289799, Example 1
COc1cnc(-c2ccccc2C(C)C)nc1N(C)Cc1ccc(-c2ccccn2)cc1
|
C27H28N4O 424.548000 |
NYQSADXSTZPZOK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771860; PubChem:CID175444705
|
Local ready
Direct docking supported
|
|
E3L041063
BDB041063
|
US20250289799, Example 2
COc1cnc(-c2ccccc2C(C)C)nc1N(C)CC1CCN(c2ccccn2)CC1
|
C26H33N5O 431.584000 |
XVXCIBOJDBJSRF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771861; PubChem:CID176244119
|
Local ready
Direct docking supported
|
|
E3L041064
BDB041064
|
US20250289799, Example 3
COc1cnc(-c2ccccc2C(C)C)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C27H28F3N5O 495.549000 |
SKDIECILFGQBFG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771862; PubChem:CID176244191
|
Local ready
Direct docking supported
|
|
E3L041065
BDB041065
|
US20250289799, Example 4
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H26F3N5O 481.522000 |
GLOWFABFNYFRQG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771863; PubChem:CID176244283
|
Local ready
Direct docking supported
|
|
E3L041066
BDB041066
|
US20250289799, Example 5
COc1cnc(-c2ccccc2C(C)C)nc1NCC1CCN(c2ccccn2)CC1
|
C25H31N5O 417.557000 |
XMGCDPDLTQXCIO-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771864; PubChem:CID176244187
|
Local ready
Direct docking supported
|
|
E3L041067
BDB041067
|
US20250289799, Example 6
COc1cnc(-c2ccccc2C(C)C)nc1NCC1CCC(c2nc(C(F)(F)F)cn2C)CC1
|
C26H32F3N5O 487.570000 |
LVWRFVMUFYTUGF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771865; PubChem:CID176244189
|
Local ready
Direct docking supported
|
|
E3L041068
BDB041068
|
US20250289799, Example 7
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-n2nc(C(F)(F)F)cc2C)cc1
|
C26H26F3N5O 481.522000 |
UKLYHSNIFXZRKQ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771866; PubChem:CID176244192
|
Local ready
Direct docking supported
|
|
E3L041069
BDB041069
|
US20250289799, Example 8
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(C)Cc1ccc(-c2nc(C(F)(F)F)cn2C)cc1
|
C26H26F3N7O2 525.535000 |
VSUQONJLTNCYJL-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771867; PubChem:CID176244154
|
Local ready
Direct docking supported
|
|
E3L041070
BDB041070
|
US20250289799, Example 9
COc1ncnc(C2CC2)c1-c1ncc2c(n1)N(Cc1ccc(-c3ccccn3)cc1)CCO2
|
C26H24N6O2 452.518000 |
LWNDRGQKPNOERY-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771868; PubChem:CID176244101
|
Local ready
Direct docking supported
|
|
E3L041071
BDB041071
|
US20250289799, Example 10
COc1ncnc(C2CC2)c1-c1ncc2c(n1)N(CC1CCN(c3ccccn3)CC1)CCO2
|
C25H29N7O2 459.554000 |
JBMKXFNCMUTDDG-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771869; PubChem:CID176244319
|
Local ready
Direct docking supported
|
|
E3L041072
BDB041072
|
US20250289799, Example 11
COc1cnc(-c2ccccc2C(C)C)nc1NCc1ccc(-c2nccn3ccnc23)cc1
|
C27H26N6O 450.546000 |
WNKQUKOROKGJOK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771870; PubChem:CID176244209
|
Local ready
Direct docking supported
|
|
E3L041073
BDB041073
|
US20250289799, Example 13
CC(C)c1ccccc1-c1ncc2c(n1)N(CC1CCC(c3nc(C(F)(F)F)cn3C)CC1)CCO2
|
C27H32F3N5O 499.581000 |
AYOSOSQIBCXLPZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771871; PubChem:CID176244136
|
Local ready
Direct docking supported
|
|
E3L041074
BDB041074
|
US20250289799, Example 13
CC(C)c1ccccc1-c1ncc2c(n1)N(CC1CCC(c3nc(C(F)(F)F)cn3C)CC1)CCO2
|
C27H32F3N5O 499.581000 |
AYOSOSQIBCXLPZ-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771872; PubChem:CID176244136
|
Local ready
Direct docking supported
|
|
E3L041075
BDB041075
|
US20250289799, Example 15
Cc1cc(C(F)(F)F)nn1-c1ccc(CN2C(=O)COc3cnc(-c4ccccc4C(C)C)nc32)cc1
|
C27H24F3N5O2 507.516000 |
NOJWELLSTVXUFF-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771873; PubChem:CID176244251
|
Local ready
Direct docking supported
|
|
E3L041076
BDB041076
|
US20250289799, Example 16
CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCc2ccc(-c3cccnc3)cc2)n1
|
C26H23F3N4 448.492000 |
IRWGRMREFMEWLK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771874; PubChem:CID177269196
|
Local ready
Direct docking supported
|
|
E3L041077
BDB041077
|
US20250289799, Example 17
CC(C)c1ccccc1-c1ncc(C(F)(F)F)c(NCc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)n1
|
C26H23F6N5 519.493000 |
WRMUGCOMIALDSU-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771875; PubChem:CID176244227
|
Local ready
Direct docking supported
|
|
E3L041078
BDB041078
|
US20250289799, Example 19
COc1cnc(-c2c(OC)ncnc2C2CC2)nc1N(C)Cc1ccc(-c2ccccn2)cc1
|
C26H26N6O2 454.534000 |
WGDBKIUOGJGZRP-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771877; PubChem:CID176244160
|
Local ready
Direct docking supported
|
|
E3L041079
BDB041079
|
US20250289799, Example 22
COc1ncnc(C2CC2)c1-c1ncc2c(n1)N(CC1CCC(c3nc(C(F)(F)F)cn3C)CC1)CCO2
|
C26H30F3N7O2 529.567000 |
NKQKNWWVWWDWHX-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771880; PubChem:CID176244158
|
Local ready
Direct docking supported
|
|
E3L041080
BDB041080
|
US20250289799, Example 23
COc1cnc(-c2ccccc2C(C)C)nc1NCC12CCC(c3ccc(C(F)(F)F)cn3)(CC1)CC2
|
C29H33F3N4O 510.604000 |
DUCBLOUCIFJDGK-UHFFFAOYSA-N | Q8TAF3 | Ubiquitin carboxyl-terminal hydrolase 1 |
BindingDB, PubChem
BindingDB:BDBM771881; PubChem:CID176244216
|
Local ready
Direct docking supported
|