| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041961
BDB041961
|
US12441708, Example 25
O=C1NCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
|
C12H9N3O4 259.221000 |
SSKPOPMQEPMDJT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777371; PubChem:CID78176832
|
Local ready
Direct docking supported
|
|
E3L041962
BDB041962
|
US12441708, Example 27
Cc1c(N2CCC(=O)NC2=O)cnc2ccccc12
|
C14H13N3O2 255.277000 |
PQKIITQTXYYOLE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777373; PubChem:CID135273274
|
Local ready
Direct docking supported
|
|
E3L041963
BDB041963
|
US12441708, Example 28
Cc1c(-n2ccc(=O)[nH]c2=O)cnc2ccccc12
|
C14H11N3O2 253.261000 |
SHIMPJGRDPIYQR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777374; PubChem:CID135273275
|
Local ready
Direct docking supported
|
|
E3L041964
BDB041964
|
US12441708, Example 29
CCOc1cc(=O)n(C2CCC(=O)NC2=O)cn1
|
C11H13N3O4 251.242000 |
FDSSSFSXMKVKBF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777375; PubChem:CID135279004
|
Local ready
Direct docking supported
|
|
E3L041965
BDB041965
|
US12441708, Example 30
CCOc1cnn(C2CCC(=O)NC2=O)c(=O)c1
|
C11H13N3O4 251.242000 |
BTKXLOUCSQGLCM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777376; PubChem:CID135279075
|
Local ready
Direct docking supported
|
|
E3L041966
BDB041966
|
US12441708, Example 31
CCOc1ccn(C2CCC(=O)NC2=O)c(=O)c1
|
C12H14N2O4 250.254000 |
GUBUKMIZLLFEKE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777377; PubChem:CID135279188
|
Local ready
Direct docking supported
|
|
E3L041967
BDB041967
|
US12441708, Example 32
O=C1CCN(c2cncc3ccccc23)C(=O)N1
|
C13H11N3O2 241.250000 |
LKFINYPABPEUDF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777378; PubChem:CID135273276
|
Local ready
Direct docking supported
|
|
E3L041968
BDB041968
|
US12441708, Example 33
O=c1ccn(-c2cnc3ccccc3c2)c(=O)[nH]1
|
C13H9N3O2 239.234000 |
VAWMMQROEGQGQI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777379; PubChem:CID135273277
|
Local ready
Direct docking supported
|
|
E3L041969
BDB041969
|
US12441708, Example 34
O=c1ccn(-c2cncc3ccccc23)c(=O)[nH]1
|
C13H9N3O2 239.234000 |
XCTUBMCHZWKQOC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777380; PubChem:CID135273279
|
Local ready
Direct docking supported
|
|
E3L041970
BDB041970
|
US12441708, Example 35
O=C1CN(C2Cc3ccccc3C2=O)C(=O)N1
|
C12H10N2O3 230.223000 |
WYDJKLOIXSTEMU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777381; PubChem:CID135273278
|
Local ready
Direct docking supported
|
|
E3L041971
BDB041971
|
US12441708, Example 36
Cc1ccncc1-n1cc(C#N)c(=O)[nH]c1=O
|
C11H8N4O2 228.211000 |
HGNSTQAPBHIJGD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777382; PubChem:CID79873752
|
Local ready
Direct docking supported
|
|
E3L041972
BDB041972
|
Deoxyuridine
O=c1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1
|
C9H12N2O5 228.204000 |
MXHRCPNRJAMMIM-SHYZEUOFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777383; PubChem:CID13712
|
Local ready
Direct docking supported
|
|
E3L041973
BDB041973
|
BDBM777384
N#Cc1cn(-c2cccnc2)c(=O)[nH]c1=O
|
C10H6N4O2 214.184000 |
SGGRKQCEMAIOQM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777384; PubChem:CID2766716
|
Local ready
Direct docking supported
|
|
E3L041974
BDB041974
|
5-Methyl-1-(3-pyridinyl)-2,4(1H,3H)-pyrimidinedione
Cc1cn(-c2cccnc2)c(=O)[nH]c1=O
|
C10H9N3O2 203.201000 |
UBGXACDTODJFHN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777385; PubChem:CID22375981
|
Local ready
Direct docking supported
|
|
E3L041975
BDB041975
|
1-(Pyridin-3-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
O=c1ccn(-c2cccnc2)c(=O)[nH]1
|
C9H7N3O2 189.174000 |
GJDOIEPECIHDNQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777386; PubChem:CID135273280
|
Local ready
Direct docking supported
|
|
E3L041976
BDB041976
|
US12441708, Example 41
Cc1cc(C(N)=O)[nH]c(=O)c1N1C(=O)c2ccccc2C1=O
|
C15H11N3O4 297.270000 |
PMKPZIFTAWSIDJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777387; PubChem:CID135273282
|
Local ready
Direct docking supported
|
|
E3L041977
BDB041977
|
US12441708, Example 42
NC(=O)c1ccc(N2C(=O)c3ccccc3C2=O)c(=O)[nH]1
|
C14H9N3O4 283.243000 |
CHFAHNKSXADGPX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777388; PubChem:CID135273281
|
Local ready
Direct docking supported
|
|
E3L041978
BDB041978
|
US12441708, Example 43
Cc1cc(C#N)[nH]c(=O)c1N1C(=O)c2ccccc2C1=O
|
C15H9N3O3 279.255000 |
SJRRHUVUCDIKES-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777389; PubChem:CID135273284
|
Local ready
Direct docking supported
|
|
E3L041979
BDB041979
|
US12441708, Example 44
N#Cc1ccc(N2C(=O)c3ccccc3C2=O)c(=O)[nH]1
|
C14H7N3O3 265.228000 |
ITEOIRFTMGNHGB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777390; PubChem:CID135273283
|
Local ready
Direct docking supported
|
|
E3L041980
BDB041980
|
BDBM781594
O=C1CCC(N2Cc3cc(CN4C[C@@H]5C[C@H]4CN5C(c4ccccc4)c4ccccc4)c(F)cc3C2=O)C(=O)N1
|
C32H31FN4O3 538.623000 |
KEOJTRAPPNIXIL-AMWOSJAMSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM781594; PubChem:CID171829297
|
Local ready
Direct docking supported
|