| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L041941
BDB041941
|
BDBM775555
C/C=C(\CN(C)C1COC1)C(=O)Nc1cccc([C@@H]2c3cnn(-c4ccccc4)c3N(CC)C(=O)[C@H]2NC(=O)c2nccc(C(F)(F)F)n2)c1
|
C35H35F3N8O4 688.711000 |
UMRWCDDLLOHIAT-QYKSNXAHSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB
BindingDB:BDBM775555
|
Local ready
Direct docking supported
|
|
E3L041942
BDB041942
|
BDBM775556
C/C=C(/C(=O)Nc1cccc([C@@H]2c3cnn(-c4ccccc4)c3N(CC)C(=O)[C@H]2NC(=O)c2nccc(C(F)(F)F)n2)c1)C(C)N1CCC1
|
C35H35F3N8O3 672.712000 |
DBPYBGDSKKFWFK-OVPFKMGZSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB
BindingDB:BDBM775556
|
Local ready
Direct docking supported
|
|
E3L041943
BDB041943
|
US12441708, Example 1
CC(C)(C)OC(=O)NCCCOCCCOc1cccc2ncc(-n3ccc(=O)[nH]c3=O)cc12
|
C24H30N4O6 470.526000 |
WORXXISVTHTMIE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777347; PubChem:CID135279148
|
Local ready
Direct docking supported
|
|
E3L041944
BDB041944
|
US12441708, Example 2
CC(C)(C)OC(=O)NCCCOCCCOc1ccc2c(-n3ccc(=O)[nH]c3=O)cncc2c1
|
C24H30N4O6 470.526000 |
CDWHQANDGFYUOZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777348; PubChem:CID135278936
|
Local ready
Direct docking supported
|
|
E3L041945
BDB041945
|
US12441708, Example 3
O=C1CCC(N2C(=O)c3cc(F)c(NCCCCCCO)cc3C2=O)C(=O)N1
|
C19H22FN3O5 391.399000 |
PDGVSEJPKBQWBQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777349; PubChem:CID135273262
|
Local ready
Direct docking supported
|
|
E3L041946
BDB041946
|
US12441708, Example 4
O=C1CCC(N2Cc3c(ccc(F)c3OCCCCCCO)C2=O)C(=O)N1
|
C19H23FN2O5 378.400000 |
HRLBXFWDUQUIEY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777350; PubChem:CID135273265
|
Local ready
Direct docking supported
|
|
E3L041947
BDB041947
|
US12441708, Example 5
O=C1CCC(N2Cc3cc(NCCCCCCO)c(F)cc3C2=O)C(=O)N1
|
C19H24FN3O4 377.416000 |
JHKFPFWDHAMTFN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777351; PubChem:CID134414452
|
Local ready
Direct docking supported
|
|
E3L041948
BDB041948
|
US12441708, Example 6
O=C1NC(C(F)(F)F)CCC1N1C(=O)c2cccc(F)c2C1=O
|
C14H10F4N2O3 330.237000 |
XGBJNZAYJGGZTH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777352; PubChem:CID135273263
|
Local ready
Direct docking supported
|
|
E3L041949
BDB041949
|
US12441708, Example 7
O=C1c2cccc(F)c2C(=O)N1c1ccc(C(F)(F)F)[nH]c1=O
|
C14H6F4N2O3 326.205000 |
JLSGUCYBGYXRAC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777353; PubChem:CID135273264
|
Local ready
Direct docking supported
|
|
E3L041950
BDB041950
|
US12441708, Example 10
CNc1ccccc1C(=O)NCCN1CCC(=O)NC1=O
|
C14H18N4O3 290.323000 |
UMIMVIGVQOCHPL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777356; PubChem:CID130431973
|
Local ready
Direct docking supported
|
|
E3L041951
BDB041951
|
US12441708, Example 11
CNc1ccccc1C(=O)NCCN1C(=O)CCNC1=O
|
C14H18N4O3 290.323000 |
XBZPRBLRGAMSJY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777357; PubChem:CID135273268
|
Local ready
Direct docking supported
|
|
E3L041952
BDB041952
|
US12441708, Example 14
O=C1CCC(N2C(=O)c3ccccc3C2=O)C2(COC2)N1
|
C15H14N2O4 286.287000 |
OZCIXBUKIVTJKJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777360; PubChem:CID102104623
|
Local ready
Direct docking supported
|
|
E3L041953
BDB041953
|
US12441708, Example 15
CCOc1cnn(C2CCC(=O)NC2=O)c(=O)c1Cl
|
C11H12ClN3O4 285.687000 |
ZIQIMWGOOOBTGA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777361; PubChem:CID135279345
|
Local ready
Direct docking supported
|
|
E3L041954
BDB041954
|
US12441708, Example 18
CN1CC(N2C(=O)c3ccccc3C2=O)C(=O)NC1=O
|
C13H11N3O4 273.248000 |
LZNLOWXWWYOBQI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777364; PubChem:CID135273269
|
Local ready
Direct docking supported
|
|
E3L041955
BDB041955
|
US12441708, Example 19
O=CN1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1
|
C13H11N3O4 273.248000 |
HABFWUQERJXSKV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777365; PubChem:CID135273270
|
Local ready
Direct docking supported
|
|
E3L041956
BDB041956
|
US12441708, Example 20
O=C1CCC(N2Cc3ccccc3C2=O)C2(COC2)N1
|
C15H16N2O3 272.304000 |
MFJFAIUXOXKWOY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777366; PubChem:CID135273271
|
Local ready
Direct docking supported
|
|
E3L041957
BDB041957
|
US12441708, Example 21
Cn1cc(N2C(=O)c3ccccc3C2=O)c(=O)[nH]c1=O
|
C13H9N3O4 271.232000 |
PICCGQBXKDBRPI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777367; PubChem:CID135273272
|
Local ready
Direct docking supported
|
|
E3L041958
BDB041958
|
US12441708, Example 22
CC1(C)C(=O)NC(=O)N1C1CC2CCCCN2C1=O
|
C13H19N3O3 265.313000 |
PWUNRPRIHWJEJT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777368; PubChem:CID135273273
|
Local ready
Direct docking supported
|
|
E3L041959
BDB041959
|
US12441708, Example 23
N#Cc1cn(-c2cnc3ccccc3c2)c(=O)[nH]c1=O
|
C14H8N4O2 264.244000 |
KGOHQBKSFDPVHT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777369; PubChem:CID79873987
|
Local ready
Direct docking supported
|
|
E3L041960
BDB041960
|
US12441708, Example 24
O=C1NC(=O)C(N2C(=O)c3cccc(F)c3C2=O)N1
|
C11H6FN3O4 263.184000 |
WSOTZYTXQNZMRG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM777370; PubChem:CID135279349
|
Local ready
Direct docking supported
|