| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L004181
BDB004181
|
US20250388593, Example 344
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(=O)n(C4CCCC(=O)NC4=O)c(=O)n(C)c3c1)c1nnc(C)n1-2
|
C45H52ClN9O6S 882.488000 |
KRCMKFOPBPLBRP-CDRRMRQFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95575; PubChem:CID177778496
|
Local ready
Direct docking supported
|
|
E3L004182
BDB004182
|
US20250388593, Example 345
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNC(=O)CN1CCC3(CCCC(=O)NC3=O)CC1=O)c1nnc(C)n1-2
|
C38H47ClN8O5S 763.365000 |
NTCBVQIWOLROIG-XRTOLJPQSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95576; PubChem:CID177778579
|
Local ready
Direct docking supported
|
|
E3L004183
BDB004183
|
US20250388593, Example 346
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CCc1ccc3c(N4CCCC(=O)NC4=O)nn(C)c3c1)c1nnc(C)n1-2
|
C43H51ClN10O4S 839.467000 |
MBTIBZGVHHQLFC-XIFFEERXSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95577; PubChem:CID177778517
|
Local ready
Direct docking supported
|
|
E3L004184
BDB004184
|
US20250388593, Example 347
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)N[C@@H](CC(=O)NCCCCCCCNC(=O)COc1cccc(C(=O)NC3CCCC(=O)NC3=O)n1)c1nnc(C)n1-2
|
C40H48ClN9O6S 818.401000 |
NOPPIIOIFWOCHG-IYQUFBQYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95578; PubChem:CID178289708
|
Local ready
Direct docking supported
|
|
E3L004185
BDB004185
|
US20250388593, Example 348
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)/C=C/c1cccc3c1N(C)C(=O)C3(C)N1C=CCC(=O)NC1=O)c1nnc(C)n1-2
|
C45H50ClN9O5S 864.473000 |
LMBLMXREIFRXGC-HAZROESFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95579; PubChem:CID177903186
|
Local ready
Direct docking supported
|
|
E3L004186
BDB004186
|
US20250388593, Example 349
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)/C=C/c1ccc([C@H]3C[C@H](N4C=CCC(=O)NC4=O)C(=O)N3C)cc1)c1nnc(C)n1-2
|
C46H52ClN9O5S 878.500000 |
MUUDDGOMDFKDOL-ZLESKCDHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95580; PubChem:CID177903210
|
Local ready
Direct docking supported
|
|
E3L004187
BDB004187
|
US20250388593, Example 350
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCNC(=O)Cn1c(=O)c(=O)n(C3CCCC(=O)NC3=O)c3ccccc31)c1nnc(C)n1-2
|
C42H46ClN9O6S 840.407000 |
LCGQKDBBERNFAL-QGFKTNLFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95581; PubChem:CID177778527
|
Local ready
Direct docking supported
|
|
E3L004188
BDB004188
|
US20250388593, Example 352
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCNC(=O)CN1C(=O)[C@@](C)(N3CCCC(=O)NC3=O)c3ccccc31)c1nnc(C)n1-2
|
C43H50ClN9O5S 840.451000 |
BCVZQZCKOCHVNL-ZUHDFBLUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95582; PubChem:CID178289709
|
Local ready
Direct docking supported
|
|
E3L004189
BDB004189
|
US20250388593, Example 354
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3cnc(N4CCC5(CCCC(=O)NC5=O)C4)nc3)CC1)c1nnc(C)n1-2
|
C48H61ClN10O4S 909.602000 |
QLZGISLMFIAEJI-LHPIIVOHSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95583; PubChem:CID171844136
|
Local ready
Direct docking supported
|
|
E3L004190
BDB004190
|
US20250388593, Example 355
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3cccc(NC45CCC(CC4)C(=O)NC5=O)c3)CC1)c1nnc(C)n1-2
|
C49H61ClN8O4S 893.599000 |
OKJAOOTVRFXNEE-NSPNILJUSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95584; PubChem:CID177778518
|
Local ready
Direct docking supported
|
|
E3L004191
BDB004191
|
US20250388593, Example 356
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3ccc(OC4CCCC(=O)NC4=O)cc3)CC1)c1nnc(C)n1-2
|
C47H58ClN7O5S 868.545000 |
GFHUCYRLWSFBPJ-SQTCDLSVSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95585; PubChem:CID178289710
|
Local ready
Direct docking supported
|
|
E3L004192
BDB004192
|
US20250388593, Example 357
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCc3c(ncnc3N3CC4(CC(=O)N(C5CCC(=O)NC5=O)C4=O)C3)C1)c1nnc(C)n1-2
|
C48H56ClN11O6S 950.567000 |
DSIYHDAIADKPDZ-KNPJQLEMSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95586; PubChem:CID177778519
|
Local ready
Direct docking supported
|
|
E3L004193
BDB004193
|
US20250388593, Example 358
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCC(=O)N1CCC(c3ccc(C45CCC(O4)C(=O)NC5=O)cc3)CC1)c1nnc(C)n1-2
|
C47H56ClN7O5S 866.529000 |
JUHQNWRFSGKHHA-RAANQGNKSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95587; PubChem:CID178289711
|
Local ready
Direct docking supported
|
|
E3L004194
BDB004194
|
US20250388593, Example 360-3
C[C@@H]1CC2c3ccccc3NC2[C@@H](c2cnc(N3CCC(CN(C)CCCCCCCc4cccc5c4n(C)c(=O)n5C4CCCC(=O)NC4=O)CC3)nc2)N1CC(C)(C)C
|
C49H69N9O3 832.151000 |
MNXUYZCHYCRTSN-GMWDRQFZSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95588; PubChem:CID178289712
|
Local ready
Direct docking supported
|
|
E3L004195
BDB004195
|
BDBM95589
CCOC(=O)c1ccc(CCCCCCCN(C)C(=O)OC(C)(C)C)cc1
|
C22H35NO4 377.525000 |
CHOJEHXYGLOTHO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM95589; PubChem:CID175638805
|
Local ready
Direct docking supported
|
|
E3L004196
BDB004196
|
BDBM96555
Cc1ccc(NC(=O)CCN2CCc3ccccc3C2)cc1
|
C19H22N2O 294.398000 |
RTIXNDCLLAJULP-UHFFFAOYSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM96555; PubChem:CID651797
|
Local ready
Direct docking supported
|
|
E3L004197
BDB004197
|
BDBM96969
O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5)CC3)CCN42)C(=O)N1
|
C45H47N5O6 753.900000 |
TYEXTZBQGMCLAT-GTNLMGJLSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM96969
|
Local ready
Direct docking supported
|
|
E3L004198
BDB004198
|
BDBM96970
O=C1CCC(N2Cc3cc4c(cc3C2=O)OC[C@@H]2CN(CC3CCN(c5ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc5F)CC3)CCN42)C(=O)N1
|
C45H46FN5O6 771.890000 |
KUTJIEUAPQAQAC-PQTOXHJOSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM96970
|
Local ready
Direct docking supported
|
|
E3L004199
BDB004199
|
BDBM96971
O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc2)CC3)C4)C(=O)N1
|
C47H47N5O7 793.921000 |
YDMQYRRRRMPTJD-PQGYCHLWSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM96971
|
Local ready
Direct docking supported
|
|
E3L004200
BDB004200
|
BDBM96972
O=C1CCC(N2C(=O)c3cc4c(cc3C2=O)CN(CC(=O)N2CCC3(CC2)CCN(c2ncc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cn2)CC3)C4)C(=O)N1
|
C45H45N7O7 795.897000 |
CXEDLWYNPGRCDG-BTHNLOPKSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM96972
|
Local ready
Direct docking supported
|