| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L005441
BDB005441
|
BDBM129938
COc1cc(C(=O)NCCO)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O4 607.538000 |
KNABCCKTMBMVKT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129938; PubChem:CID86766991
|
Local ready
Direct docking supported
|
|
E3L005442
BDB005442
|
BDBM129939
COc1cc(C(=O)NC(C)C)ccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H34Cl2N4O3 605.566000 |
GPZBMYSYCTYIPQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129939; PubChem:CID86766992
|
Local ready
Direct docking supported
|
|
E3L005443
BDB005443
|
BDBM129940
CCc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C30H29Cl2N3O 518.488000 |
JYHLEWWCXRHGDJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129940; PubChem:CID86766993
|
Local ready
Direct docking supported
|
|
E3L005444
BDB005444
|
BDBM129941
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
IFRGIPSPDFJEEX-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129941; PubChem:CID86766994
|
Local ready
Direct docking supported
|
|
E3L005445
BDB005445
|
BDBM129942
COc1ccc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
IFRGIPSPDFJEEX-NDEPHWFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129942; PubChem:CID86766995
|
Local ready
Direct docking supported
|
|
E3L005446
BDB005446
|
BDBM129943
COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccn1)C2=O
|
C28H26Cl2N4O3 537.447000 |
QBXJLAAPXWWIJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129943; PubChem:CID86766996
|
Local ready
Direct docking supported
|
|
E3L005447
BDB005447
|
BDBM129944
COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)[C@@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H34Cl2N4O3 605.566000 |
SREKLQZSZRMJMY-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129944; PubChem:CID86766997
|
Local ready
Direct docking supported
|
|
E3L005448
BDB005448
|
BDBM129945
COc1ccc(C(=O)NC(C)C)cc1-c1nc2c(n1C(C)C)[C@H](c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C33H34Cl2N4O3 605.566000 |
SREKLQZSZRMJMY-LJAQVGFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129945; PubChem:CID86766998
|
Local ready
Direct docking supported
|
|
E3L005449
BDB005449
|
BDBM129946
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cnc1C)C2=O
|
C28H26Cl2N4O2 521.448000 |
WIYMFNQNNGEZMB-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129946; PubChem:CID86766999
|
Local ready
Direct docking supported
|
|
E3L005450
BDB005450
|
BDBM129947
COc1ccc(CNC(=O)CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O4 607.538000 |
ZBFNQGJLOPNHTH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129947; PubChem:CID71680281
|
Local ready
Direct docking supported
|
|
E3L005451
BDB005451
|
BDBM129948
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(CCO)c1)C2=O
|
C29H28Cl2N4O4 567.473000 |
OARARBUSYWXFDH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129948; PubChem:CID86767000
|
Local ready
Direct docking supported
|
|
E3L005452
BDB005452
|
BDBM129949
COCCn1cc(N2C(=O)c3nc(-c4ccccc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
|
C30H30Cl2N4O4 581.500000 |
IVNOWFPIAWUUAY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129949; PubChem:CID86767001
|
Local ready
Direct docking supported
|
|
E3L005453
BDB005453
|
BDBM129950
COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H26Cl2N4O3 537.447000 |
VHEASBLFWBZTKJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129950; PubChem:CID86767002
|
Local ready
Direct docking supported
|
|
E3L005454
BDB005454
|
BDBM129951
CCn1cc(N2C(=O)c3nc(-c4ccccc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
|
C29H28Cl2N4O3 551.474000 |
CPRKJVDYRLJFER-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129951; PubChem:CID86767003
|
Local ready
Direct docking supported
|
|
E3L005455
BDB005455
|
BDBM129952
CC(C)n1c(-c2ccnc(N)c2)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C25H20Cl2FN5O 496.373000 |
NRQJFOUPSSTZJN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129952; PubChem:CID71680282
|
Local ready
Direct docking supported
|
|
E3L005456
BDB005456
|
BDBM129953
COc1ccc(C(O)C(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C31H30Cl2FN3O3 582.503000 |
FTFIHRBCYHTZGJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129953; PubChem:CID86767004
|
Local ready
Direct docking supported
|
|
E3L005457
BDB005457
|
BDBM129954
COc1ccc(C(C)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C29H26Cl2FN3O3 554.449000 |
WPBMVRLEKQLMCW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129954; PubChem:CID86767005
|
Local ready
Direct docking supported
|
|
E3L005458
BDB005458
|
BDBM129956
COc1nnc(C(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O
|
C28H25Cl2FN6O3 583.451000 |
DKYCLMGWDCHJJO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129956; PubChem:CID71680443
|
Local ready
Direct docking supported
|
|
E3L005459
BDB005459
|
BDBM129957
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cn(C)c1=O)C2=O
|
C29H26Cl2N6O3 577.472000 |
FXONYZNEWIUOBK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129957; PubChem:CID71680444
|
Local ready
Direct docking supported
|
|
E3L005460
BDB005460
|
BDBM129958
COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1C)N(c1cccc(Cl)c1F)C2=O
|
C30H24ClFN6O2 555.013000 |
YPJZWJQOABXYTF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM129958; PubChem:CID86767007
|
Local ready
Direct docking supported
|