| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006201
BDB006201
|
BDBM143446
COCCCOc1cc(Cl)ccc1C1(C)c2c(nn(-c3ccccc3OC)c2C(C)C)C(=O)N1c1cccc(Cl)c1F
|
C32H32Cl2FN3O4 612.529000 |
JRKKFIPIACRKRQ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143446; PubChem:CID91801036
|
Local ready
Direct docking supported
|
|
E3L006202
BDB006202
|
BDBM143447
COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CN1CCCC1)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C34H35Cl2FN4O3 637.583000 |
ILSKQZCULNKRSM-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143447; PubChem:CID89601663
|
Local ready
Direct docking supported
|
|
E3L006203
BDB006203
|
BDBM143450
CNC(=O)c1ccc(C)c(-n2nc3c(c2C(C)C)C(c2ccc(C(F)(F)F)cc2)N(c2cc(Cl)ccc2C)C3=O)c1
|
C31H28ClF3N4O2 581.038000 |
CRWXYYDAMBWTKL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143450; PubChem:CID89601389
|
Local ready
Direct docking supported
|
|
E3L006204
BDB006204
|
BDBM143452
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cn1)N(c1ccc(F)c(Cl)c1)C2=O
|
C26H21Cl2FN4O2 511.384000 |
QVEOEHNRKHXHRY-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143452; PubChem:CID89601517
|
Local ready
Direct docking supported
|
|
E3L006205
BDB006205
|
BDBM143453
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O
|
C27H24Cl2N4O2 507.421000 |
LQBNBLSVDLZZMI-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143453; PubChem:CID71585178
|
Local ready
Direct docking supported
|
|
E3L006206
BDB006206
|
BDBM143454
COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C30H28Cl2FN3O4 584.475000 |
APMMFMOKBQIPHF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143454; PubChem:CID89601665
|
Local ready
Direct docking supported
|
|
E3L006207
BDB006207
|
BDBM143455
COc1ccccc1-n1nc2c(c1C(C)C)C(CCO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O
|
C29H26Cl2FN3O3 554.449000 |
HIJODUHTEZNTAC-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143455; PubChem:CID89601902
|
Local ready
Direct docking supported
|
|
E3L006208
BDB006208
|
BDBM143457
CNC(=O)c1ccc(OC)c(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c1
|
C31H30Cl2N4O3 577.512000 |
WKMPZXXAZAQLQZ-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143457; PubChem:CID89601286
|
Local ready
Direct docking supported
|
|
E3L006209
BDB006209
|
BDBM143461
COc1ccc(C(=O)NCCN2CCCC2)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C36H39Cl2N5O3 660.646000 |
YVYATCZGDDDVSH-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143461; PubChem:CID89602004
|
Local ready
Direct docking supported
|
|
E3L006210
BDB006210
|
BDBM143462
[C-]#[N+]c1cc(Cl)cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)c1
|
C29H24Cl2N4O2 531.443000 |
ZWEMDKNKMRHEQA-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143462; PubChem:CID91801038
|
Local ready
Direct docking supported
|
|
E3L006211
BDB006211
|
BDBM143463
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cc(C(N)=O)c1)C2=O
|
C29H26Cl2N4O3 549.458000 |
PSDOESHRXCBYKA-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143463; PubChem:CID89601754
|
Local ready
Direct docking supported
|
|
E3L006212
BDB006212
|
BDBM143464
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cc(NC(C)=O)c1)C2=O
|
C30H28Cl2N4O3 563.485000 |
PAUGXEQSQVHHPG-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143464; PubChem:CID89601396
|
Local ready
Direct docking supported
|
|
E3L006213
BDB006213
|
BDBM143465
COc1ccc(C(=O)N(C)C)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O
|
C32H32Cl2N4O3 591.539000 |
RCVRAHVEDDYMCE-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143465; PubChem:CID89601774
|
Local ready
Direct docking supported
|
|
E3L006214
BDB006214
|
BDBM143466
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(F)c(F)c1)C2=O
|
C27H22ClF2N3O2 493.941000 |
RZBALPLOLRLLGL-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143466; PubChem:CID89601332
|
Local ready
Direct docking supported
|
|
E3L006215
BDB006215
|
BDBM143467
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C27H24Cl2N4O3 523.420000 |
RQXAUHYKZHXCFO-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143467; PubChem:CID89601327
|
Local ready
Direct docking supported
|
|
E3L006216
BDB006216
|
BDBM143468
CCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2)cc(Cl)c1=O
|
C28H26Cl2N4O3 537.447000 |
FZVOKZVDSZAECZ-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143468; PubChem:CID89601961
|
Local ready
Direct docking supported
|
|
E3L006217
BDB006217
|
BDBM143469
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O
|
C28H26Cl2N4O3 537.447000 |
LJQVUKZVORGQEL-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143469; PubChem:CID89601199
|
Local ready
Direct docking supported
|
|
E3L006218
BDB006218
|
BDBM143470
COc1ccccc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)c(=O)n(CCO)c1)C2=O
|
C28H26Cl2N4O4 553.446000 |
YPYQBKQPNRSJLU-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143470; PubChem:CID71585179
|
Local ready
Direct docking supported
|
|
E3L006219
BDB006219
|
BDBM143472
COCCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
|
C30H30Cl2N4O4 581.500000 |
MOELCFOKAVJOMF-UHFFFAOYSA-N | O15151, Q00987 | Protein Mdm4, E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM143472; PubChem:CID71585275
|
Local ready
Direct docking supported
|
|
E3L006220
BDB006220
|
BDBM143473
CCn1cc(N2C(=O)c3nn(-c4ccccc4OC)c(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O
|
C29H28Cl2N4O3 551.474000 |
IBXWQDNBFLGQOV-UHFFFAOYSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM143473; PubChem:CID71585276
|
Local ready
Direct docking supported
|