E3 Ligase Ligand Database

MGD and E3 ligand related compounds for browsing and docking.
Reset
Structure similarity search Input SMILES or upload SDF/MOL/MOL2/PDB/PDBQT; results use Morgan fingerprint Tanimoto.
67228 compounds match the current filters. 123739 source records are linked to them.
Compound ID Name Formula / MW InChIKey E3 Target Source Docking structure
E3L062961
BDB062961
 BDBM50607698
CC(C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)COCCOCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C84H111N19O26S
1834.986000		 NXOOQBFFDXRNCK-LUIZJZQYSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607698
 Local ready
Direct docking supported
E3L062962
BDB062962
 BDBM50607699
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1C/C=C/C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C72H86N14O21S
1515.624000		 GBSSQVYKTPDZOZ-VYWZAESESA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607699
 Local ready
Direct docking supported
E3L062963
BDB062963
 BDBM50607700
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1C/C=C\CC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H88N14O21S
1529.651000		 LOWNMGBSMQTWIP-GLVZFHOMSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607700
 Local ready
Direct docking supported
E3L062964
BDB062964
 BDBM50607701
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CC/C=C/C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H88N14O21S
1529.651000		 GUZCNRRZLJHXOF-QXGYUHGKSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607701
 Local ready
Direct docking supported
E3L062965
BDB062965
 BDBM50607702
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CC/C=C/CC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C74H90N14O21S
1543.678000		 LECDVOKMLCQMEP-HPNRSYJASA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607702
 Local ready
Direct docking supported
E3L062966
BDB062966
 BDBM50607703
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H90N14O21S
1531.667000		 RWDZNZQNIGWZJH-UICXZYIGSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607703
 Local ready
Direct docking supported
E3L062967
BDB062967
 BDBM50607704
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCCCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C74H92N14O21S
1545.694000		 FXLAGHGNAGPJGH-YQFBZIEGSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607704
 Local ready
Direct docking supported
E3L062968
BDB062968
 BDBM50607705
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1C/C=C\CC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H88N14O21S
1529.651000		 LOWNMGBSMQTWIP-QMNMSOBWSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607705
 Local ready
Direct docking supported
E3L062969
BDB062969
 BDBM50607706
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CC/C=C/C[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H88N14O21S
1529.651000		 GUZCNRRZLJHXOF-NYFRUPHESA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607706
 Local ready
Direct docking supported
E3L062970
BDB062970
 BDBM50607707
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CC/C=C/CC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C74H90N14O21S
1543.678000		 LECDVOKMLCQMEP-LAVKINTNSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607707
 Local ready
Direct docking supported
E3L062971
BDB062971
 BDBM50607708
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCCC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C73H90N14O21S
1531.667000		 RWDZNZQNIGWZJH-PGFRBXMFSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607708
 Local ready
Direct docking supported
E3L062972
BDB062972
 BDBM50607709
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CCCCCC[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc32)C(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(C)C
 C74H92N14O21S
1545.694000		 FXLAGHGNAGPJGH-QBZGUAMPSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607709
 Local ready
Direct docking supported
E3L062973
BDB062973
 BDBM50607710
CC(C)[C@H](NC(=O)COCCOCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(N)=O
 C68H81N13O24S
1496.530000		 MYFSESRFSSSFDZ-YBAZSGAOSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607710
 Local ready
Direct docking supported
E3L062974
BDB062974
 BDBM50607711
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C70H84N14O23S
1521.584000		 YLYAKPXOUMRJMY-DLSBNUFUSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607711
 Local ready
Direct docking supported
E3L062975
BDB062975
 BDBM50607712
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cccc(F)c1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C70H83FN14O23S
1539.574000		 QBWRFKHHWQEROP-DJRMSAAUSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607712
 Local ready
Direct docking supported
E3L062976
BDB062976
 BDBM50607713
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C71H86N14O23S
1535.611000		 CPIPCXRMIZHILV-OBTOJNNPSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607713
 Local ready
Direct docking supported
E3L062977
BDB062977
 BDBM50607714
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C76H88N14O23S
1597.682000		 QCNKDSJWOJFCOY-TZZKQGOXSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607714
 Local ready
Direct docking supported
E3L062978
BDB062978
 BDBM50607715
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(F)c(F)c1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C70H82F2N14O23S
1557.564000		 FRZNMMKKSJMTPN-NCWNSJLUSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607715
 Local ready
Direct docking supported
E3L062979
BDB062979
 BDBM50607716
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C70H83FN14O23S
1539.574000		 VJJPYHHTTNKPBY-DJRMSAAUSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607716
 Local ready
Direct docking supported
E3L062980
BDB062980
 BDBM50607717
CC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21)C(N)=O)C(C)C
 C70H83BrN14O23S
1600.480000		 ASTGJZHWOAPURB-DJRMSAAUSA-N Q9BQA1 Protein arginine N-methyltransferase 5
BindingDB
BindingDB:BDBM50607717
 Local ready
Direct docking supported