| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066058
LIG000628
|
3
Cc1cscc1-c1cn(C2CCC(=O)NC2=O)nn1
|
C12H12N4O2S 276.321000 |
IKMCNWXOYROHAP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1297
|
Local ready
Direct docking supported
|
|
E3L066059
LIG000629
|
LIG000629
O=C1CCC(N2Cc3cccc(Cl)c3C2=O)C(=O)N1
|
C13H11ClN2O3 278.695000 |
ILDRNMVJVXPPFT-UHFFFAOYSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:171
|
Local ready
Direct docking supported
|
|
E3L066060
LIG000630
|
EM12-SO2Im(4-F)
O=C1CCC(N2Cc3ccc(S(=O)(=O)n4cnc(F)c4)cc3C2=O)C(=O)N1
|
C16H13FN4O5S 392.368000 |
ILGQLADLOFGMQZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630773; MolGlueDB:MGDB1253
|
Local ready
Direct docking supported
|
|
E3L066061
LIG000631
|
L2
COC(=O)CCNC(=O)c1nn(-c2ccc(C)c(C)c2)c(=O)n(Cc2ccccc2)c1=O
|
C23H24N4O5 436.468000 |
ILMYJZNNEMYLKJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB610
|
Local ready
Direct docking supported
|
|
E3L066062
LIG000632
|
LIG000632
C[C@H](N)C(=O)N[C@H]1CC(=O)NC1=O
|
C7H11N3O3 185.183000 |
IMCUIUMUCWYBAW-IMJSIDKUSA-N | Q96SW2 | - |
e3_ligand
e3_ligand:110
|
Local ready
Direct docking supported
|
|
E3L066063
LIG000633
|
10
O=C1CCC(Nc2ccccc2)C(=O)N1
|
C11H12N2O2 204.229000 |
IMJAVZDZCOZXOZ-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, e3_ligand, MolGlueDB
BindingDB:BDBM575328; e3_ligand:80; MolGlueDB:MGDB898
|
Local ready
Direct docking supported
|
|
E3L066064
LIG000634
|
74
O=C1CCC(N2C(=O)c3ccc(NC(=O)C4CC4)cc3C2=O)C(=O)N1
|
C17H15N3O5 341.323000 |
IMNOSOHCMZEAPE-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB961
|
Local ready
Direct docking supported
|
|
E3L066065
LIG000635
|
InsP6
O=P(O)(O)OC1C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1OP(=O)(O)O
|
C6H18O24P6 660.030000 |
IMQLKJBTEOYOSI-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1294
|
Local ready
Direct docking supported
|
|
E3L066066
LIG000636
|
14
CN(CCCOCCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)CC1CCC(n2cc3cc(NC(=O)c4cccc(C(F)(F)F)n4)c(C(C)(C)O)cc3n2)CC1
|
C44H51F3N8O7 860.935000 |
INCVUGCZQZUSSU-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB527
Related BindingDB:BDBM50639839
|
Local ready
Direct docking supported
|
|
E3L066067
LIG000637
|
UOM-005845
CN(C)c1ccc(C(=O)Nc2ncc(SCc3cccnc3)s2)cc1
|
C18H18N4OS2 370.503000 |
INKVHBAUKUYTPB-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1482
|
Local ready
Direct docking supported
|
|
E3L066068
LIG000638
|
compound20
O=C1CCC(n2cc(-c3csc(C(=O)NC4CC4)c3)nn2)C(=O)N1
|
C15H15N5O3S 345.384000 |
INRUKTVOMYKZEO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1048
|
Local ready
Direct docking supported
|
|
E3L066069
LIG000639
|
70
O=C1CCC(N2C(=O)c3cccc(NC(=O)c4cnccn4)c3C2=O)C(=O)N1
|
C18H13N5O5 379.332000 |
INZYWDNPLAGHJM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB977
|
Local ready
Direct docking supported
|
|
E3L066070
LIG000640
|
HQ021
NC(=O)c1ccccc1NC(=O)Cc1csc(Nc2ccccn2)n1
|
C17H15N5O2S 353.407000 |
IOFFPPJYBLBCGR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB774
|
Local ready
Direct docking supported
|
|
E3L066071
LIG000641
|
19
CCCCNc1c(F)cc(C(=O)NC2CCC(=O)NC2=O)c(F)c1OC
|
C17H21F2N3O4 369.368000 |
IONAEGMCSLASDU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630605; MolGlueDB:MGDB444
|
Local ready
Direct docking supported
|
|
E3L066072
LIG000642
|
8e
COc1ccc(Br)cc1S(=O)(=O)Nc1cc2c(C)noc2cc1OCC(=O)NCCCCCCNc1ccc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C36H37BrN6O10S 825.695000 |
IOPVJNHGIHWYNG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB643
|
Local ready
Direct docking supported
|
|
E3L066073
LIG000643
|
18
CN(CCCO[C@H]1C[C@H](Nc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)C1)C[C@H]1CC[C@H](n2cc3cc(NC(=O)c4cccc(C(F)(F)F)n4)ccc3n2)CC1
|
C42H45F3N8O6 814.866000 |
IPHIYOXVUOYUTO-KWWSLGSDSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50639843; MolGlueDB:MGDB523
|
Local ready
Direct docking supported
|
|
E3L066074
LIG000644
|
14p
Cc1ccnc(SCC2CCC(=O)NC2=O)n1
|
C11H13N3O2S 251.311000 |
IPNSVNXZWDZYMC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625134; MolGlueDB:MGDB402
|
Local ready
Direct docking supported
|
|
E3L066075
LIG000645
|
11e
Nc1ccc(C(=O)NC2CCC(=O)NC2=O)c(O)c1
|
C12H13N3O4 263.253000 |
IPUAAMOPTISHEC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630600; MolGlueDB:MGDB800
|
Local ready
Direct docking supported
|
|
E3L066076
LIG000646
|
9b
Cc1ccc(NC(=O)CCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1Cl
|
C23H20ClN3O5 453.882000 |
IRDBZSYSXQQJQO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB335
|
Local ready
Direct docking supported
|
|
E3L066077
LIG000647
|
GBD-13
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1CCCN(C(=O)CCCCCCCCCCNc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)C1
|
C46H51N9O6 825.971000 |
IRHJWGMAWWUWEA-XRRNFBIGSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB835
|
Local ready
Direct docking supported
|