| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066078
LIG000648
|
HQ010
Cc1cnc(NC(=O)Cc2csc(Nc3ccccn3)n2)s1
|
C14H13N5OS2 331.426000 |
IRVKFRZWUBEJNQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB401
|
Local ready
Direct docking supported
|
|
E3L066079
LIG000649
|
DS12
CC[C@H](CO)Nc1nc(NCC2CCCCC2)c2ncn(C(C)C)c2n1
|
C19H32N6O 360.506000 |
ISKQJAZIOLAANN-OAHLLOKOSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1593
|
Local ready
Direct docking supported
|
|
E3L066080
LIG000650
|
24
CC[C@H](CO)Nc1nc(NCc2ccc(N3CCNCC3)cc2)c2ncn(C(C)C)c2n1
|
C23H34N8O 438.580000 |
ITAKCBJQHUHRFE-GOSISDBHSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB222
|
Local ready
Direct docking supported
|
|
E3L066081
LIG000651
|
Compound 4
CCCOc1ccccc1CNS(=O)(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C23H26N4O6S 486.550000 |
ITEGYANFEQIFQM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB456
|
Local ready
Direct docking supported
|
|
E3L066082
LIG000652
|
7
O=C1CCC(N2Cc3c(ccc4c3OCC43CCC(Oc4ccccc4)CC3)C2=O)C(=O)N1
|
C26H26N2O5 446.503000 |
ITFRCOVKUZIAMR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1458
|
Local ready
Direct docking supported
|
|
E3L066083
LIG000653
|
22a
O=C1CCC(N2C(=O)c3ccc(C4=C[C@]4(C(=O)OCC(Cl)(Cl)Cl)c4ccc(Br)cc4)cc3C2=O)C(=O)N1
|
C25H16BrCl3N2O6 626.674000 |
ITKMEHIIJSOLLY-LUTIACGYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB996
|
Local ready
Direct docking supported
|
|
E3L066084
LIG000654
|
Lib-B-14O
O=C(COc1ccccc1-c1cccc2c1CN(C1CCC(=O)NC1=O)C2=O)N/N=C/c1ccc(-c2ccc(O)cn2)cc1
|
C33H27N5O6 589.608000 |
ITWJAWNFLBKBTJ-QNVXDBMFSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB868
|
Local ready
Direct docking supported
|
|
E3L066085
LIG000655
|
I1
CCn1c(=O)c(C#N)nn(-c2ccccc2)c1=O
|
C12H10N4O2 242.238000 |
IUJFPSYSWZFIDA-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB461
|
Local ready
Direct docking supported
|
|
E3L066086
LIG000656
|
EM12-SO2Pyr(3-F)
O=C1CCC(N2Cc3ccc(S(=O)(=O)n4ccc(F)n4)cc3C2=O)C(=O)N1
|
C16H13FN4O5S 392.368000 |
IUXYXXBAHQMFKK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630776; MolGlueDB:MGDB1250
|
Local ready
Direct docking supported
|
|
E3L066087
LIG000657
|
T02
O=C1CCC(N2C(=O)c3ccc(NCCOCCOCCOCc4ccccc4)cc3C2=O)C(=O)N1
|
C26H29N3O7 495.532000 |
IVMMBGFLQUZRCJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB965
|
Local ready
Direct docking supported
|
|
E3L066088
LIG000658
|
12
Cc1ccc(C(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)cc1
|
C21H17N3O5 391.383000 |
IVMUUHKIZMAKOC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB320
|
Local ready
Direct docking supported
|
|
E3L066089
LIG000659
|
2E
CCOc1cccc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1
|
C21H20N2O4 364.401000 |
IVUWMWVFBWRGJR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB501
|
Local ready
Direct docking supported
|
|
E3L066090
LIG000660
|
8
O=C1CCC(N2Cc3cc(NCCc4ccc5ccccc5c4)ccc3C2=O)C(=O)N1
|
C25H23N3O3 413.477000 |
IWBAXZPQJLIEHP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1232
|
Local ready
Direct docking supported
|
|
E3L066091
LIG000661
|
LC-02-117
O=C1CC[C@H](N2Cc3cc(-c4cnn5ccc(NCCc6ccccc6)nc45)ccc3C2=O)C(=O)N1
|
C27H24N6O3 480.528000 |
IWELENJZEKXIMC-QFIPXVFZSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB923
|
Local ready
Direct docking supported
|
|
E3L066092
LIG000662
|
6a
COc1cc2onc(C)c2cc1NS(=O)(=O)c1cc(Br)ccc1OCC(=O)NCCNC(=O)COc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C34H31BrN6O12S 827.623000 |
IWEPBTCCMICWOT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB734
|
Local ready
Direct docking supported
|
|
E3L066093
LIG000663
|
24
CC(C)(O)c1cc2nn([C@H]3CC[C@H](CN4CCC5(CC4)CC(CNc4cccc6c4C(=O)N(C4CCC(=O)NC4=O)C6=O)C5)CC3)cc2cc1NC(=O)c1cccc(C(F)(F)F)n1
|
C46H51F3N8O6 868.958000 |
IWOVTMLUFGDAGD-OBYWWQMUSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50639848; MolGlueDB:MGDB124
|
Local ready
Direct docking supported
|
|
E3L066094
LIG000664
|
Z1694588468
O=C1CCC(Sc2nc3ccccc3s2)C(=O)N1
|
C12H10N2O2S2 278.358000 |
IXBHCWWOBJRSKM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB895
|
Local ready
Direct docking supported
|
|
E3L066095
LIG000665
|
ZZ7-16-063
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N[C@@H]2CCCN(C(=O)c3cccc4ccccc34)C2)ncc1Cl
|
C29H30ClN5O3S 564.111000 |
IXPDPUXPOYTXLT-OAQYLSRUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB167
|
Local ready
Direct docking supported
|
|
E3L066096
LIG000666
|
CC-220
O=C1CC[C@H](N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
|
C25H27N3O5 449.507000 |
IXZOHGPZAQLIBH-NRFANRHFSA-N | Q16531, Q96SW2 | Protein cereblon, DNA damage-binding protein 1 |
BindingDB, MolGlueDB
BindingDB:BDBM65497; MolGlueDB:MGDB916
|
Local ready
Direct docking supported
|
|
E3L066099
LIG000669
|
CC-220
O=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
|
C25H27N3O5 449.507000 |
IXZOHGPZAQLIBH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1158
|
Local ready
Direct docking supported
|