| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007361
BDB007361
|
BDBM170280
CN(C)CC(=O)N1CCN(C(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)c(F)cc43)[C@H]2c2cccc(Cl)c2)CC1
|
C31H38Cl2FN5O3 618.581000 |
RWOXESFVJKFUSP-QQZZJUGLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170280
|
Local ready
Direct docking supported
|
|
E3L007362
BDB007362
|
BDBM170281
CN(C)CCC(=O)N1CCN(C(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)c(F)cc43)[C@H]2c2cccc(Cl)c2)CC1
|
C32H40Cl2FN5O3 632.608000 |
ILVROSWTCMNMOT-AJFCMVSNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170281
|
Local ready
Direct docking supported
|
|
E3L007363
BDB007363
|
BDBM170283
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCC(O)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H37Cl2FN4O3 591.555000 |
JONMIQIHZVPUFE-PYOQLBSMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170283
|
Local ready
Direct docking supported
|
|
E3L007364
BDB007364
|
BDBM170284
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H]2CC[C@H](NS(C)(=O)=O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H38Cl2F2N4O4S 671.638000 |
KVGNQDANXXNKBE-JQKNNJKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170284
|
Local ready
Direct docking supported
|
|
E3L007365
BDB007365
|
BDBM170285
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H]2CC[C@H](N)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H36Cl2F2N4O2 593.546000 |
XLNRKVVOIJBASQ-YZLIUWOKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170285
|
Local ready
Direct docking supported
|
|
E3L007366
BDB007366
|
BDBM170286
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCCNS(C)(=O)=O)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C27H32Cl2F2N4O4S 617.546000 |
GVFHKTBGRZEYPI-VJNNQTCJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170286
|
Local ready
Direct docking supported
|
|
E3L007367
BDB007367
|
BDBM170287
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCNS(C)(=O)=O)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C26H30Cl2F2N4O4S 603.519000 |
MDSIBTAOZOCZMV-QDQHVZQESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170287
|
Local ready
Direct docking supported
|
|
E3L007368
BDB007368
|
BDBM170288
C[C@H](N)C(=O)OC1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C32H39Cl2FN4O4 633.592000 |
NSAFCVYUZIQKHJ-WAWILOFOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170288
|
Local ready
Direct docking supported
|
|
E3L007369
BDB007369
|
BDBM170289
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(N)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C29H35Cl2FN4O2 561.529000 |
YZLMHCPVZTXDRG-MUTWLIAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170289; PubChem:CID52937985
|
Local ready
Direct docking supported
|
|
E3L007370
BDB007370
|
BDBM170290
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCNCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C28H33Cl2FN4O2 547.502000 |
QWGGQSWRWUTYCU-WZRJCJTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170290; PubChem:CID52937937
|
Local ready
Direct docking supported
|
|
E3L007371
BDB007371
|
BDBM170291
CC(=O)N1CCC(NC(=O)[C@@H]2N[C@H](CC(C)(C)C)[C@]3(C(=O)Nc4cc(Cl)ccc43)[C@H]2c2cccc(Cl)c2F)CC1
|
C30H35Cl2FN4O3 589.539000 |
GGZUBZIFLQTHQP-HVHHDALESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170291; PubChem:CID52937938
|
Local ready
Direct docking supported
|
|
E3L007372
BDB007372
|
BDBM170292
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCN(CCO)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C30H37Cl2FN4O3 591.555000 |
WBZUWLYAOUGKLA-HVHHDALESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170292
|
Local ready
Direct docking supported
|
|
E3L007373
BDB007373
|
BDBM170293
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCN(CC(C)(C)O)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C32H41Cl2FN4O3 619.609000 |
VJHDDQJWKWUWEC-PVZLDOBLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170293
|
Local ready
Direct docking supported
|
|
E3L007374
BDB007374
|
BDBM170294
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCC(NS(=O)(=O)C(F)(F)F)CC2)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H34Cl2F4N4O4S 693.591000 |
QRAVGMFIBQNBCQ-MUTWLIAXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170294
|
Local ready
Direct docking supported
|
|
E3L007375
BDB007375
|
BDBM170295
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CCN(S(=O)(=O)C(F)(F)F)CC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C29H32Cl2F4N4O4S 679.564000 |
KPVDNVGZRAUKCT-WZRJCJTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170295
|
Local ready
Direct docking supported
|
|
E3L007376
BDB007376
|
BDBM170296
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@](C)(O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C28H34Cl2FN3O4 566.501000 |
XYYVDPJBKLNVGV-AZXVBEQTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170296
|
Local ready
Direct docking supported
|
|
E3L007377
BDB007377
|
BDBM170297
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@@](C)(O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C28H34Cl2FN3O4 566.501000 |
XYYVDPJBKLNVGV-PUBYHYAISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170297
|
Local ready
Direct docking supported
|
|
E3L007378
BDB007378
|
BDBM170298
O=C(NC1CCC(O)CC1)[C@@H]1N[C@H](CC2CCCC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H34Cl2FN3O3 574.524000 |
ZDYVCXVZHZFCCZ-CTPKDOPXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170298; PubChem:CID52938741
|
Local ready
Direct docking supported
|
|
E3L007379
BDB007379
|
BDBM170299
O=C(NC1CCC(O)CC1)[C@@H]1N[C@H](C=C2CCCC2)[C@]2(C(=O)Nc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F
|
C30H32Cl2FN3O3 572.508000 |
YKCVEPHDYMRWRN-CTPKDOPXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170299; PubChem:CID69927265
|
Local ready
Direct docking supported
|
|
E3L007380
BDB007380
|
BDBM170300
CC(C)(C)C[C@H]1N[C@@H](C(=O)NC2CN(CC(C)(C)O)C2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(Cl)ccc12
|
C30H37Cl2FN4O3 591.555000 |
YULZGKMBFRLRAQ-ZWXBAZLCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170300
|
Local ready
Direct docking supported
|