| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L007401
BDB007401
|
BDBM170322
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CC2CC2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C26H28Cl2FN3O4 536.431000 |
PODRKMGRPAVHNA-WKYIVVMRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170322; PubChem:CID69928335
|
Local ready
Direct docking supported
|
|
E3L007402
BDB007402
|
BDBM170323
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCc2ccsc2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C28H28Cl2FN3O4S 592.520000 |
IGJHQFKCBJZQPJ-DTWKNNLDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170323
|
Local ready
Direct docking supported
|
|
E3L007403
BDB007403
|
BDBM170326
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1CCCc1ccccc1
|
C32H34Cl2FN3O4 614.545000 |
CGLZSFZJVNLXMD-KATLIUSOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170326
|
Local ready
Direct docking supported
|
|
E3L007404
BDB007404
|
BDBM170327
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCCc2cccs2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C29H30Cl2FN3O4S 606.547000 |
JNLYCLSPNIATOJ-FYESPONXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170327
|
Local ready
Direct docking supported
|
|
E3L007405
BDB007405
|
BDBM170328
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1CCCc1cccs1
|
C30H32Cl2FN3O4S 620.574000 |
MYLFXWUXEYJTMB-VVGNQINPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170328
|
Local ready
Direct docking supported
|
|
E3L007406
BDB007406
|
BDBM170329
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCC2CCCC2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C29H34Cl2FN3O4 578.512000 |
JPKUIMNTNGMQIA-SYRIZIHISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170329; PubChem:CID69927606
|
Local ready
Direct docking supported
|
|
E3L007407
BDB007407
|
BDBM170330
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1CCC1CCCC1
|
C30H36Cl2FN3O4 592.539000 |
IBPTYCBQGGSKOK-QMSAFVIYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170330
|
Local ready
Direct docking supported
|
|
E3L007408
BDB007408
|
BDBM170331
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1CCc1cccs1
|
C29H30Cl2FN3O4S 606.547000 |
KKJPEPGPPBOWRS-FYESPONXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170331
|
Local ready
Direct docking supported
|
|
E3L007409
BDB007409
|
US9079913, MI-715B
O=C(NCC[C@H](O)CO)[C@@H]1N[C@H](CCc2ccco2)[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@H]1c1cccc(Cl)c1
|
C28H28Cl2FN3O5 576.452000 |
TVVJULHBMASWRE-USJLZIQHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170332; PubChem:CID69926979
|
Local ready
Direct docking supported
|
|
E3L007410
BDB007410
|
US9079913, MI-519-10-me
CN1[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]2(C(=O)Nc3cc(F)c(F)cc32)[C@H]1CC(C)(C)C
|
C28H33ClF3N3O4 568.036000 |
NCVZNOICJNGHGC-BGCYMAIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170338; PubChem:CID58254243
|
Local ready
Direct docking supported
|
|
E3L007411
BDB007411
|
BDBM170339
CC(C)(C)C[C@@H]1[C@]2(C(=O)Nc3cc(Cl)c(F)cc32)[C@@H](c2cccc(Cl)c2)[C@H](C(=O)NCC[C@H](O)CO)[N+]1(C)C
|
C29H37Cl2FN3O4+ 581.536000 |
FLNMRJUUSLATHA-HXXBZNTPSA-O | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170339
|
Local ready
Direct docking supported
|
|
E3L007412
BDB007412
|
BDBM170340
CCC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C28H34Cl2FN3O4 566.501000 |
YOHZOMMSBACNQB-FKUBJEGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170340; PubChem:CID69926746
|
Local ready
Direct docking supported
|
|
E3L007413
BDB007413
|
BDBM170341
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C29H34ClF3N4O3 579.063000 |
NYMWVKCHMDGVMM-BGLPIVGWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170341
|
Local ready
Direct docking supported
|
|
E3L007414
BDB007414
|
BDBM170343
CCC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2F)[C@@]12C(=O)Nc1cc(F)c(F)cc12
|
C29H35ClF3N3O4 582.063000 |
BMICMZACTKVOBC-SUGRGTCJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170343
|
Local ready
Direct docking supported
|
|
E3L007415
BDB007415
|
BDBM170344
CCCCC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H38Cl2FN3O4 594.555000 |
HOXWEECFOQRYLG-OPMYFTJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170344; PubChem:CID69927617
|
Local ready
Direct docking supported
|
|
E3L007416
BDB007416
|
BDBM170345
CC(C)CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C30H38Cl2FN3O4 594.555000 |
CAXITIVEGQAKIH-OPMYFTJMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170345
|
Local ready
Direct docking supported
|
|
E3L007417
BDB007417
|
BDBM170346
CC(C)CC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H40Cl2FN3O4 608.582000 |
PIWKUUTZFWFIOL-RFHZMROGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170346
|
Local ready
Direct docking supported
|
|
E3L007418
BDB007418
|
BDBM170347
CC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1c(Cl)cccc12
|
C27H33Cl2N3O4 534.484000 |
CGXXPSRYCOMPPV-XSWDNSQFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170347; PubChem:CID69926671
|
Local ready
Direct docking supported
|
|
E3L007419
BDB007419
|
BDBM170348
CCCCC(C)(C)C[C@H]1N(C)[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C31H40Cl2FN3O4 608.582000 |
ZFLZYDMLKYMRQF-RFHZMROGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM170348
|
Local ready
Direct docking supported
|
|
E3L007420
BDB007420
|
BDBM170349
CCCC(C)(C)C[C@H]1N[C@@H](C(=O)NCC[C@H](O)CO)[C@H](c2cccc(Cl)c2)[C@@]12C(=O)Nc1cc(Cl)c(F)cc12
|
C29H36Cl2FN3O4 580.528000 |
MNRBJBSVKSOPJJ-HXXBZNTPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM170349; PubChem:CID69927548
|
Local ready
Direct docking supported
|